AMN and STAMBP

Number of citations of the paper that reports this interaction (PMID 16730941)
46

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		AMN	STAMBP
Gene Name		amnion associated transmembrane protein	STAM binding protein
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Plasma Membrane Endosome Membrane Integral Component Of Membrane Apical Plasma Membrane Endocytic Vesicle Extracellular Vesicular Exosome	Nucleus Nucleoplasm Cytoplasm Early Endosome Plasma Membrane Cleavage Furrow Extracellular Vesicular Exosome
	Molecular Function	Receptor Binding	Ubiquitin-specific Protease Activity Protein Binding Metallopeptidase Activity Metal Ion Binding
	Biological Process	Vitamin Metabolic Process Water-soluble Vitamin Metabolic Process Receptor-mediated Endocytosis Multicellular Organismal Development Excretion Cobalamin Metabolic Process Cobalamin Transport Lipoprotein Metabolic Process Golgi To Plasma Membrane Protein Transport Small Molecule Metabolic Process	Mitotic Cytokinesis Proteolysis JAK-STAT Cascade Positive Regulation Of Cell Proliferation Negative Regulation Of Phosphatidylinositol 3-kinase Signaling Protein Deubiquitination Negative Regulation Of Neuron Apoptotic Process Negative Regulation Of Ras Protein Signal Transduction
Pathways		Lipoprotein metabolism Metabolism of vitamins and cofactors Defective CD320 causes methylmalonic aciduria Defective LMBRD1 causes methylmalonic aciduria and homocystinuria type cblF Metabolism of lipids and lipoproteins Defective BTD causes biotidinase deficiency Defective MMACHC causes methylmalonic aciduria and homocystinuria type cblC Defective MTR causes methylmalonic aciduria and homocystinuria type cblG Defective MTRR causes methylmalonic aciduria and homocystinuria type cblE Defective AMN causes hereditary megaloblastic anemia 1 Defects in cobalamin (B12) metabolism Defective GIF causes intrinsic factor deficiency Defective HLCS causes multiple carboxylase deficiency Defective MMAB causes methylmalonic aciduria type cblB Lipid digestion, mobilization, and transport Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD Defective MMAA causes methylmalonic aciduria type cblA Defective CUBN causes hereditary megaloblastic anemia 1 Cobalamin (Cbl, vitamin B12) transport and metabolism HDL-mediated lipid transport Defective MUT causes methylmalonic aciduria mut type Metabolism of water-soluble vitamins and cofactors Defects in biotin (Btn) metabolism Defective TCN2 causes hereditary megaloblastic anemia Defects in vitamin and cofactor metabolism
Drugs		Hydroxocobalamin
Diseases
GWAS
Protein-Protein Interactions		1 interactors: STAMBP	39 interactors: ALAS1 AMN BMPR1B CASR CHMP1A CHMP1B CHMP2A CHMP3 CHMP4A CHMP4B CHMP4C CHMP5 CLTC CTNNBL1 CYP2C9 EPS15 GRAP2 GRB2 ITGA5 MAP2K5 MAP3K2 NTPCR PJA1 RECQL5 RNF11 SMAD2 SMAD6 SMAD7 SPG7 STAM STAM2 TNFRSF1A TRAF6 TRIP13 UACA UBC UBE2S USP21 USP28
Entrez ID		81693	10617
HPRD ID		09314	05877
Ensembl ID		ENSG00000166126	ENSG00000124356
Uniprot IDs		Q9BXJ7	O95630
PDB IDs			2XZE 3RZU 3RZV
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Phosphatidylinositol 3-kinase Signaling Mitotic Cytokinesis JAK-STAT Cascade Negative Regulation Of Ras Protein Signal Transduction Negative Regulation Of Small GTPase Mediated Signal Transduction Regulation Of Phosphatidylinositol 3-kinase Signaling Cytokinesis Protein Deubiquitination Protein Modification By Small Protein Removal Negative Regulation Of Neuron Apoptotic Process Negative Regulation Of Neuron Death Regulation Of Neuron Apoptotic Process	Cell Separation After Cytokinesis Regulation Of Mitotic Spindle Assembly Regulation Of Spindle Assembly Mitotic Metaphase Plate Congression Regulation Of Mitotic Spindle Organization Metaphase Plate Congression Vacuolar Transport Regulation Of Centrosome Duplication Establishment Of Chromosome Localization Endosomal Transport Regulation Of Centrosome Cycle Mitotic Sister Chromatid Segregation Mitotic Nuclear Division Sister Chromatid Segregation Chromosome Segregation Positive Regulation Of Viral Release From Host Cell Nucleus Organization Cell Division Regulation Of Microtubule Cytoskeleton Organization Cell Cycle Process Intracellular Transport Membrane Organization Mitotic Cell Cycle Process Regulation Of Microtubule-based Process Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Viral Process Negative Regulation Of ERBB Signaling Pathway Protein Transport Mitotic Cell Cycle Viral Life Cycle Establishment Of Localization In Cell Establishment Of Protein Localization Regulation Of Mitotic Nuclear Division Regulation Of Protein Complex Assembly Regulation Of Viral Release From Host Cell Cellular Localization Virion Assembly Cell Cycle Enzyme Linked Receptor Protein Signaling Pathway Protein Localization Viral Budding Via Host ESCRT Complex Regulation Of Cellular Component Organization Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of ERBB Signaling Pathway Regulation Of Signaling Viral Budding Intracellular Signal Transduction Establishment Of Organelle Localization Regulation Of Cell Cycle Process Regulation Of Cytoskeleton Organization
Tagcloud ?		14q32 allantois amnion amnionless backcross cd40bp chorion craf1 e10 e9 ectoderm extraembryonic gastrulation insertional interspecific lap1 ltbetar lymphotoxin meets mesoderm notochord resorbed somites streak synteny trafamn trafs transducing transgene
Tagcloud (Difference) ?		14q32 allantois amnion amnionless backcross cd40bp chorion craf1 e10 e9 ectoderm extraembryonic gastrulation insertional interspecific lap1 ltbetar lymphotoxin meets mesoderm notochord resorbed somites streak synteny trafamn trafs transducing transgene
Tagcloud (Intersection) ?