AMN

Gene Name		amnion associated transmembrane protein
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Plasma Membrane Endosome Membrane Integral Component Of Membrane Apical Plasma Membrane Endocytic Vesicle Extracellular Vesicular Exosome
	Molecular Function	Receptor Binding
	Biological Process	Vitamin Metabolic Process Water-soluble Vitamin Metabolic Process Receptor-mediated Endocytosis Multicellular Organismal Development Excretion Cobalamin Metabolic Process Cobalamin Transport Lipoprotein Metabolic Process Golgi To Plasma Membrane Protein Transport Small Molecule Metabolic Process
Pathways		Lipoprotein metabolism Metabolism of vitamins and cofactors Defective CD320 causes methylmalonic aciduria Defective LMBRD1 causes methylmalonic aciduria and homocystinuria type cblF Metabolism of lipids and lipoproteins Defective BTD causes biotidinase deficiency Defective MMACHC causes methylmalonic aciduria and homocystinuria type cblC Defective MTR causes methylmalonic aciduria and homocystinuria type cblG Defective MTRR causes methylmalonic aciduria and homocystinuria type cblE Defective AMN causes hereditary megaloblastic anemia 1 Defects in cobalamin (B12) metabolism Defective GIF causes intrinsic factor deficiency Defective HLCS causes multiple carboxylase deficiency Defective MMAB causes methylmalonic aciduria type cblB Lipid digestion, mobilization, and transport Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD Defective MMAA causes methylmalonic aciduria type cblA Defective CUBN causes hereditary megaloblastic anemia 1 Cobalamin (Cbl, vitamin B12) transport and metabolism HDL-mediated lipid transport Defective MUT causes methylmalonic aciduria mut type Metabolism of water-soluble vitamins and cofactors Defects in biotin (Btn) metabolism Defective TCN2 causes hereditary megaloblastic anemia Defects in vitamin and cofactor metabolism
Drugs		Hydroxocobalamin
Diseases
GWAS
Protein-protein Interactions		1 interactors: STAMBP
Entrez ID		81693
HPRD ID		09314
Ensembl ID		ENSG00000166126
Uniprot IDs		Q9BXJ7
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Phosphatidylinositol 3-kinase Signaling Mitotic Cytokinesis JAK-STAT Cascade Negative Regulation Of Ras Protein Signal Transduction Negative Regulation Of Small GTPase Mediated Signal Transduction Regulation Of Phosphatidylinositol 3-kinase Signaling Cytokinesis Protein Deubiquitination Protein Modification By Small Protein Removal Negative Regulation Of Neuron Apoptotic Process Negative Regulation Of Neuron Death Regulation Of Neuron Apoptotic Process
Tagcloud ?		14q32 allantois amnion amnionless backcross cd40bp chorion craf1 e10 e9 ectoderm extraembryonic gastrulation insertional interspecific lap1 ltbetar lymphotoxin meets mesoderm notochord resorbed somites streak synteny trafamn trafs transducing transgene