CCNL2 and SRSF2

Number of citations of the paper that reports this interaction (PubMedID 14684736)
0

Data Source:
HPRD (in vivo)

		CCNL2	SRSF2
Description		cyclin L2	serine and arginine rich splicing factor 2
Image		No pdb structure
GO Annotations	Cellular Component	Cyclin-dependent Protein Kinase Holoenzyme Complex Nucleus Nucleoplasm Nuclear Speck	Nucleus Nucleoplasm Cytosol PML Body Nuclear Speck
	Molecular Function	Protein Binding Cyclin-dependent Protein Serine/threonine Kinase Regulator Activity	Nucleic Acid Binding Transcription Corepressor Activity RNA Binding MRNA Binding Protein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Regulation Of Apoptotic Process Regulation Of RNA Splicing Regulation Of Centrosome Cycle Regulation Of Cell Cycle	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Negative Regulation Of DNA-templated Transcription
Pathways			Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway mRNA 3'-end processing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS		Inflammatory bowel disease ( 28067908) Ulcerative colitis ( 28067908)
Interacting Genes		15 interacting genes: CDK11B DYRK1A EMD FAM90A1 KRTAP12-2 MAGEB2 MDFI PIH1D2 POLR2A RUNDC3A SRSF2 SRSF7 TRIM41 USP20 ZBTB7B	36 interacting genes: ADAP1 BARD1 CCNL1 CCNL2 CDK12 CDK6 CEP72 CIRSR CSNK2A1 DMRTB1 FUS GEMIN2 GOLGA2 KAT5 KRT31 KRT40 LIG4 LZTS2 NCF1 PRCC PRPF6 SCAF11 SNRNP70 SREK1 SRSF11 SRSF3 SRSF4 TCF4 TRA2B TRIM27 U2AF1 UBQLN4 USP40 YTHDC1 ZRANB2 ZRSR2
Entrez ID		81669	6427
HPRD ID		10815	02888
Ensembl ID		ENSG00000221978	ENSG00000161547
Uniprot IDs		Q96S94	Q01130 Q53FN0
PDB IDs			2KN4 2LEA 2LEB 2LEC
Enriched GO Terms of Interacting Partners?		Regulation Of RNA Splicing Regulation Of MRNA Processing Regulation Of Alternative MRNA Splicing, Via Spliceosome Regulation Of MRNA Metabolic Process Negative Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Splicing Positive Regulation Of RNA Splicing Negative Regulation Of RNA Metabolic Process Histone H3T45 Kinase Activity TMEM240-body Negative Regulation Of NK T Cell Proliferation	RNA Splicing MRNA Processing MRNA Metabolic Process Nuclear Speck RNA Processing Nucleic Acid Metabolic Process RNA Splicing, Via Transesterification Reactions Regulation Of RNA Splicing Nucleoplasm RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Nucleus Spliceosomal Complex Nucleic Acid Binding Regulation Of MRNA Processing RNA Binding Macromolecule Metabolic Process Cyclin-dependent Protein Kinase Holoenzyme Complex Spliceosomal Complex Assembly Regulation Of MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome Regulation Of MRNA Metabolic Process Regulation Of Alternative MRNA Splicing, Via Spliceosome Negative Regulation Of Double-strand Break Repair Via Homologous Recombination Regulation Of Double-strand Break Repair Via Homologous Recombination Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Aggrephagy Regulation Of RNA Metabolic Process Protein-RNA Complex Assembly Pre-mRNA 3'-splice Site Binding U2AF Complex Negative Regulation Of Autophagy Negative Regulation Of Double-strand Break Repair Negative Regulation Of DNA Repair Regulation Of DNA Repair Regulation Of Autophagy Negative Regulation Of Catabolic Process Negative Regulation Of DNA Recombination MRNA Binding Regulation Of DNA Recombination Double-strand Break Repair Via Classical Nonhomologous End Joining Regulation Of Double-strand Break Repair Double-strand Break Repair Via Nonhomologous End Joining Membraneless Organelle Assembly Cellular Response To Glucose Stimulus Aggrephagy Protein Targeting To Vacuole Involved In Autophagy Sequence-specific MRNA Binding Regulation Of Hematopoietic Stem Cell Differentiation Cellular Response To Carbohydrate Stimulus
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