NRBP1 and RAC3

Number of citations of the paper that reports this interaction (PMID 11956649)
2

Data Source:
HPRD (in vitro)

		NRBP1	RAC3
Gene Name		nuclear receptor binding protein 1	ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cell Cortex Endomembrane System Membrane Lamellipodium Perinuclear Region Of Cytoplasm	Cytosol Plasma Membrane Endomembrane System Lamellipodium Growth Cone Filamentous Actin Neuron Projection Neuronal Cell Body Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome Cell Periphery
	Molecular Function	Protein Kinase Activity Protein Binding ATP Binding Protein Homodimerization Activity	GTPase Activity Protein Binding GTP Binding Calcium-dependent Protein Binding
	Biological Process	Transcription Initiation From RNA Polymerase II Promoter Protein Phosphorylation ER To Golgi Vesicle-mediated Transport Gene Expression	Small GTPase Mediated Signal Transduction Metabolic Process Cell Projection Assembly Actin Cytoskeleton Organization Neuron Projection Development Positive Regulation Of Cell Adhesion Mediated By Integrin Intracellular Signal Transduction Neuromuscular Process Controlling Balance Regulation Of Small GTPase Mediated Signal Transduction Positive Regulation Of Substrate Adhesion-dependent Cell Spreading
Pathways		Generic Transcription Pathway Nuclear Receptor transcription pathway	Rho GTPase cycle Signaling by Rho GTPases Signaling by Wnt PCP/CE pathway beta-catenin independent WNT signaling
Drugs
Diseases
GWAS		Hypertriglyceridemia ( 23505323)
Protein-Protein Interactions		11 interactors: CDKN1A CSNK2B GADD45A GSK3B LRIF1 MLF1 PPP1CC RAC3 RIBC2 TK1 TSC22D4	9 interactors: ANKRD11 AR ARHGDIA ARHGDIB CIB1 ESR1 HNF1A NRBP1 RARA
Entrez ID		29959	5881
HPRD ID		05819	03629
Ensembl ID		ENSG00000115216	ENSG00000169750
Uniprot IDs		Q9UHY1	P60763
PDB IDs			2C2H 2G0N 2IC5 2OV2 2QME
Enriched GO Terms of Interacting Partners?		Cell Cycle Cell Cycle Arrest Response To External Stimulus Response To Abiotic Stimulus Negative Regulation Of Protein Kinase Activity Negative Regulation Of Kinase Activity Tube Development Positive Regulation Of Protein Phosphorylation Regulation Of Protein Kinase Activity Response To Organic Substance Regulation Of Kinase Activity Cellular Metabolic Process Negative Regulation Of Transferase Activity Negative Regulation Of Protein Phosphorylation Cellular Response To Ionizing Radiation Glycogen Metabolic Process Positive Regulation Of Phosphorylation Cellular Response To Heat Positive Regulation Of Protein Modification Process Cellular Response To Mechanical Stimulus Response To Hormone Fetal Process Involved In Parturition Negative Regulation Of Phosphorylation Polysaccharide Metabolic Process Cellular Response To Organic Substance Positive Regulation Of Reactive Oxygen Species Metabolic Process Cell Cycle Process Nucleobase-containing Compound Metabolic Process Regulation Of Protein Phosphorylation Signal Transduction In Response To DNA Damage Response To Radiation Negative Regulation Of Cell Cycle Positive Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Type B Pancreatic Cell Development Skeletal Muscle Cell Proliferation Superior Temporal Gyrus Development Heterocycle Metabolic Process Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Cellular Aromatic Compound Metabolic Process Response To Heat Positive Regulation Of Cell-substrate Adhesion Positive Regulation Of Protein Metabolic Process Cellular Nitrogen Compound Metabolic Process Re-entry Into Mitotic Cell Cycle Negative Regulation Of Neuron Maturation Regulation Of Phosphorylation Negative Regulation Of Protein Serine/threonine Kinase Activity Phosphatidylinositol-mediated Signaling Energy Reserve Metabolic Process Digestive Tract Development	Transcription Initiation From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Prostate Gland Development Intracellular Steroid Hormone Receptor Signaling Pathway Developmental Process Involved In Reproduction Steroid Hormone Mediated Signaling Pathway Transcription From RNA Polymerase II Promoter Regulation Of Signal Transduction Hormone-mediated Signaling Pathway Regulation Of Signaling Multicellular Organismal Development Intracellular Estrogen Receptor Signaling Pathway Growth Gland Development Reproductive Structure Development Reproductive System Development Cellular Response To Steroid Hormone Stimulus Single Organism Reproductive Process Positive Regulation Of Metabolic Process Intracellular Receptor Signaling Pathway Cellular Response To Estrogen Stimulus Regulation Of Cell Adhesion Reproductive Process Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Developmental Process Regulation Of Apoptotic Process Response To Organic Substance Regulation Of Establishment Of Protein Localization To Plasma Membrane Regulation Of Cell Death System Development Regulation Of Protein Localization Sex Differentiation Positive Regulation Of Cell Proliferation Face Development Regulation Of Protein Localization To Plasma Membrane Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Intracellular Signal Transduction Rho Protein Signal Transduction Negative Regulation Of Apoptotic Process Organ Development Negative Regulation Of Programmed Cell Death Cellular Response To Organic Substance Negative Regulation Of Cell Death Urogenital System Development Organ Morphogenesis Cellular Response To Organic Cyclic Compound Positive Regulation Of Transcription From RNA Polymerase II Promoter Anatomical Structure Development Negative Regulation Of Integrin Biosynthetic Process Positive Regulation Of Male Germ Cell Proliferation
Tagcloud ?			accessible acetyltransferases aspects cloned coactivator concert condensed cor corepressor corepressors deacetylases entry era establish extensively generate hormone initiate modulate replaced repressed repression smrt src1 steroid theme tif2 transcriptionally unliganded
Tagcloud (Difference) ?			accessible acetyltransferases aspects cloned coactivator concert condensed cor corepressor corepressors deacetylases entry era establish extensively generate hormone initiate modulate replaced repressed repression smrt src1 steroid theme tif2 transcriptionally unliganded
Tagcloud (Intersection) ?