NRBP1 and SNX31

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		NRBP1	SNX31
Description		nuclear receptor binding protein 1	sorting nexin 31
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cell Cortex Endomembrane System Membrane Lamellipodium Cell Projection	Early Endosome Protein-containing Complex
	Molecular Function	Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Protein Homodimerization Activity	Protein Binding Phosphatidylinositol Binding
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport DNA Damage Response	Intracellular Protein Transport Protein Transport Endocytic Recycling
Pathways		Nuclear Receptor transcription pathway
Drugs
Diseases
GWAS		Bone mineral density (total hip) ( 29883787) Creatinine levels ( 31015462) Crohn's disease ( 28067908) Hypertriglyceridemia ( 23505323) Inflammatory bowel disease ( 28067908) Takayasu arteritis ( 25604533)	Body mass index ( 26426971) Brain morphology (MOSTest) ( 32665545) Cerebrospinal fluid beta-site APP cleaving enzyme levels ( 29751835) Cerebrospinal fluid clusterin levels ( 26545630) Colorectal cancer ( 34062886) Diastolic blood pressure ( 28135244) HDL cholesterol levels in HIV infection ( 33109212) Periventricular white matter hyperintensities ( 32517579) Waist-hip ratio ( 28552196)
Interacting Genes		17 interacting genes: BCL2L13 BTG3 CDKN1A CIMIP5 CSNK2B GADD45A GSK3B LRIF1 MLF1 PPP1CC RAC3 RIBC2 SNX31 SORBS3 TIAM1 TK1 TSC22D4	4 interacting genes: GOPC LZTS2 NRBP1 RAC1
Entrez ID		29959	169166
HPRD ID		05819	17545
Ensembl ID		ENSG00000115216	ENSG00000174226
Uniprot IDs		F8W6G1 Q9UHY1	Q8N9S9
PDB IDs
Enriched GO Terms of Interacting Partners?		Intracellular Signaling Cassette Wnt Signaling Pathway Regulation Of Dopaminergic Neuron Differentiation	Positive Regulation Of Ovarian Follicle Development Negative Regulation Of Interleukin-23 Production Lamellipodium Regulation Of ERK5 Cascade Rho GDP-dissociation Inhibitor Binding Angiotensin-activated Signaling Pathway Involved In Heart Process Cell Cortex Embryonic Olfactory Bulb Interneuron Precursor Migration Cellular Localization Regulation Of Protein Localization Cerebral Cortex GABAergic Interneuron Development Regulation Of Cell Adhesion Involved In Heart Morphogenesis Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Negative Regulation Of Anion Channel Activity Primary Ureteric Bud Growth Negative Regulation Of Protein Localization Kinocilium Regulation Of Ovarian Follicle Development Wnt Signaling Pathway G Protein-coupled Receptor Signaling Pathway Involved In Heart Process Auditory Receptor Cell Morphogenesis Positive Regulation Of Skeletal Muscle Acetylcholine-gated Channel Clustering Erythrocyte Enucleation Hepatocyte Growth Factor Receptor Signaling Pathway Engulfment Of Apoptotic Cell Vesicle-mediated Transport Cell Projection Tangential Migration From The Subventricular Zone To The Olfactory Bulb Intracellular Transport Golgi Vesicle Transport Ureter Morphogenesis Regulation Of Neuron Maturation Regulation Of Skeletal Muscle Acetylcholine-gated Channel Clustering Microtubule Severing Positive Regulation Of Bicellular Tight Junction Assembly Regulation Of Interleukin-23 Production Thioesterase Binding Positive Regulation Of Receptor Clustering Negative Regulation Of Fibroblast Migration Establishment Of Localization In Cell Negative Regulation Of Protein Localization To Cell Surface Spindle Midzone Assembly Midbrain Dopaminergic Neuron Differentiation Ruffle Assembly Regulation Of Monoatomic Anion Transport Regulation Of Hydrogen Peroxide Metabolic Process NADPH Oxidase Complex Sphingosine-1-phosphate Receptor Signaling Pathway Sphingolipid Mediated Signaling Pathway Positive Regulation Of Ruffle Assembly
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