UQCRQ and POLR2M

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		UQCRQ	POLR2M
Gene Name		ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa	polymerase (RNA) II (DNA directed) polypeptide M
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Respiratory Chain	Nuclear Envelope DNA-directed RNA Polymerase II, Holoenzyme Neuronal Cell Body
	Molecular Function	Ubiquinol-cytochrome-c Reductase Activity	DNA-directed RNA Polymerase Activity
	Biological Process	Subthalamus Development Pons Development Cerebellar Purkinje Cell Layer Development Hippocampus Development Thalamus Development Hypothalamus Development Pyramidal Neuron Development Respiratory Electron Transport Chain Midbrain Development Cellular Metabolic Process Small Molecule Metabolic Process Hydrogen Ion Transmembrane Transport	RNA Biosynthetic Process Maintenance Of ER Location
Pathways		Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. Respiratory electron transport The citric acid (TCA) cycle and respiratory electron transport
Drugs
Diseases
GWAS
Protein-Protein Interactions		3 interactors: ERCC8 OPTN POLR2M	19 interactors: AHSP ANKHD1 APOD CEBPG DGKZ HIGD1B KIAA1377 MYO3A MYO9A NEDD4 PSMC2 RBM4B RPL7A SCMH1 SIVA1 THAP1 UQCRQ WDR89 ZNF410
Entrez ID		27089	81488
HPRD ID		17941	07575
Ensembl ID			ENSG00000255529
Uniprot IDs		O14949	P0CAP1 P0CAP2 Q6EEV4
PDB IDs			2KXS
Enriched GO Terms of Interacting Partners?		Maintenance Of ER Location Endoplasmic Reticulum Localization Negative Regulation Of Receptor Recycling Golgi Ribbon Formation Protein Targeting To Golgi Golgi To Plasma Membrane Protein Transport Establishment Of Protein Localization To Golgi Retrograde Transport, Vesicle Recycling Within Golgi Regulation Of Receptor Recycling Response To X-ray Golgi To Plasma Membrane Transport Positive Regulation Of DNA Repair Defense Response To Gram-negative Bacterium Transcription-coupled Nucleotide-excision Repair Protein Localization To Golgi Apparatus Protein Autoubiquitination	Viral Process Regulation Of Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Negative Regulation Of T Cell Migration Negative Regulation Of Lipoprotein Lipid Oxidation Transmission Of Virus Development Involved In Symbiotic Interaction Mitotic G1 DNA Damage Checkpoint Mitotic G1/S Transition Checkpoint G1 DNA Damage Checkpoint Negative Regulation Of Smooth Muscle Cell-matrix Adhesion Subthalamus Development Negative Regulation Of Cytokine Production Involved In Inflammatory Response Regulation Of Lipoprotein Lipid Oxidation Mitotic DNA Damage Checkpoint Regulation Of Smooth Muscle Cell-matrix Adhesion Negative Regulation Of Monocyte Chemotactic Protein-1 Production Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Mitotic DNA Integrity Checkpoint Interaction With Host Regulation Of Mitotic Cell Cycle Negative Regulation Of Lymphocyte Migration Regulation Of Intracellular Transport Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Progesterone Receptor Signaling Pathway Developmental Process
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