MFAP5 and MEGF6

Number of citations of the paper that reports this interaction (PubMedID 12122015)
0

Data Source:
HPRD (two hybrid)

		MFAP5	MEGF6
Description		microfibril associated protein 5	multiple EGF like domains 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Microfibril Extracellular Region Extracellular Matrix	Extracellular Region
	Molecular Function	Extracellular Matrix Structural Constituent	Calcium Ion Binding Protein Binding
	Biological Process	Embryonic Eye Morphogenesis Definitive Hemopoiesis Supramolecular Fiber Organization
Pathways		Elastic fibre formation Molecules associated with elastic fibres Molecules associated with elastic fibres
Drugs
Diseases
GWAS			Chronic central serous retinopathy ( 30073298) Systemic mastocytosis ( 32752121)
Interacting Genes		4 interacting genes: FBLN1 FBN1 FBN2 MEGF6	11 interacting genes: ATN1 ATXN7 CACNA1A CRKL EGFR GFI1B HOXA1 MBD1 MFAP5 NUFIP2 SHANK3
Entrez ID		8076	1953
HPRD ID		03063	11973
Ensembl ID		ENSG00000197614	ENSG00000162591
Uniprot IDs		B3KW70 F5GYX4 F5H413 Q13361	A0A8V8TL19 O75095
PDB IDs
Enriched GO Terms of Interacting Partners?		Sequestering Of TGFbeta In Extracellular Matrix Calcium Ion Binding Extracellular Matrix Structural Constituent Sequestering Of Extracellular Ligand From Receptor Extracellular Negative Regulation Of Signal Transduction Extracellular Matrix Constituent Conferring Elasticity Microfibril Embryonic Eye Morphogenesis Extracellular Matrix Eye Morphogenesis Maintenance Of Protein Location Sensory Organ Morphogenesis Maintenance Of Location Camera-type Eye Development Basement Membrane Extracellular Region Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Hormone Activity Embryonic Organ Morphogenesis Eye Development Glucose Metabolic Process Integrin Binding Negative Regulation Of Transformation Of Host Cell By Virus Activation Of Protein Kinase A Activity Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Hexose Metabolic Process Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Sensory Organ Development Regulation Of Transformation Of Host Cell By Virus Positive Regulation Of Substrate-dependent Cell Migration, Cell Attachment To Substrate Monosaccharide Metabolic Process Carbohydrate Homeostasis Glucose Homeostasis Sequestering Of BMP In Extracellular Matrix Positive Regulation Of Response To Food Positive Regulation Of Appetite Elastic Fiber Negative Regulation Of Osteoclast Development Fibrinogen Binding Post-embryonic Eye Morphogenesis Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Bone Trabecula Formation Negative Regulation Of Signal Transduction Peptidase Activator Activity Blood Coagulation, Fibrin Clot Formation Regulation Of Osteoclast Development Regulation Of Cellular Response To Growth Factor Stimulus Protein-containing Complex Binding Negative Regulation Of Cell Communication Negative Regulation Of Signaling	Nuclear Matrix Postsynaptic Specialization Assembly Postsynaptic Specialization Organization Animal Organ Morphogenesis
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