MEGF6 and MFAP5

Number of citations of the paper that reports this interaction (PubMedID 12122015)
0

Data Source:
HPRD (two hybrid)

		MEGF6	MFAP5
Description		multiple EGF like domains 6	microfibril associated protein 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region	Microfibril Extracellular Region Extracellular Matrix
	Molecular Function	Calcium Ion Binding Protein Binding	Extracellular Matrix Structural Constituent
	Biological Process		Embryonic Eye Morphogenesis Definitive Hemopoiesis Supramolecular Fiber Organization
Pathways			Elastic fibre formation Molecules associated with elastic fibres Molecules associated with elastic fibres
Drugs
Diseases
GWAS		Chronic central serous retinopathy ( 30073298) Systemic mastocytosis ( 32752121)
Interacting Genes		11 interacting genes: ATN1 ATXN7 CACNA1A CRKL EGFR GFI1B HOXA1 MBD1 MFAP5 NUFIP2 SHANK3	4 interacting genes: FBLN1 FBN1 FBN2 MEGF6
Entrez ID		1953	8076
HPRD ID		11973	03063
Ensembl ID		ENSG00000162591	ENSG00000197614
Uniprot IDs		A0A8V8TL19 O75095	B3KW70 F5GYX4 F5H413 Q13361
PDB IDs
Enriched GO Terms of Interacting Partners?		Nuclear Matrix Postsynaptic Specialization Assembly Postsynaptic Specialization Organization Animal Organ Morphogenesis	Sequestering Of TGFbeta In Extracellular Matrix Calcium Ion Binding Extracellular Matrix Structural Constituent Sequestering Of Extracellular Ligand From Receptor Extracellular Negative Regulation Of Signal Transduction Extracellular Matrix Constituent Conferring Elasticity Microfibril Embryonic Eye Morphogenesis Extracellular Matrix Eye Morphogenesis Maintenance Of Protein Location Sensory Organ Morphogenesis Maintenance Of Location Camera-type Eye Development Basement Membrane Extracellular Region Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Hormone Activity Embryonic Organ Morphogenesis Eye Development Glucose Metabolic Process Integrin Binding Negative Regulation Of Transformation Of Host Cell By Virus Activation Of Protein Kinase A Activity Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Hexose Metabolic Process Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Sensory Organ Development Regulation Of Transformation Of Host Cell By Virus Positive Regulation Of Substrate-dependent Cell Migration, Cell Attachment To Substrate Monosaccharide Metabolic Process Carbohydrate Homeostasis Glucose Homeostasis Sequestering Of BMP In Extracellular Matrix Positive Regulation Of Response To Food Positive Regulation Of Appetite Elastic Fiber Negative Regulation Of Osteoclast Development Fibrinogen Binding Post-embryonic Eye Morphogenesis Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Bone Trabecula Formation Negative Regulation Of Signal Transduction Peptidase Activator Activity Blood Coagulation, Fibrin Clot Formation Regulation Of Osteoclast Development Regulation Of Cellular Response To Growth Factor Stimulus Protein-containing Complex Binding Negative Regulation Of Cell Communication Negative Regulation Of Signaling
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