RNF6

Gene Name		ring finger protein (C3H2C3 type) 6
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm PML Body Axon Nuclear Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	DNA Binding Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Ligase Activity Androgen Receptor Binding
	Biological Process	Regulation Of Transcription, DNA-templated Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Axon Extension Protein K27-linked Ubiquitination Positive Regulation Of Transcription, DNA-templated Regulation Of Androgen Receptor Signaling Pathway Protein K48-linked Ubiquitination Protein K6-linked Ubiquitination
Pathways		Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS
Protein-protein Interactions		3 interactors: AR UBE2D1 UBE2H
Entrez ID		6049
HPRD ID		05027
Ensembl ID		ENSG00000127870
Uniprot IDs		B4DDP0 Q9Y252
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein K48-linked Ubiquitination Negative Regulation Of Integrin Biosynthetic Process Transcription Initiation From RNA Polymerase II Promoter Protein Polyubiquitination DNA-templated Transcription, Initiation Positive Regulation Of Integrin Biosynthetic Process Regulation Of Integrin Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase III Promoter Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Ubiquitination Protein Modification By Small Protein Conjugation Protein Catabolic Process Protein K11-linked Ubiquitination Regulation Of Transcription From RNA Polymerase III Promoter Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Cellular Macromolecule Catabolic Process Transcription From RNA Polymerase II Promoter Mitotic Spindle Assembly Checkpoint Androgen Receptor Signaling Pathway Spindle Assembly Checkpoint Mitotic Spindle Checkpoint Negative Regulation Of Chromosome Segregation Regulation Of Establishment Of Protein Localization To Plasma Membrane Spindle Checkpoint Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Nuclear Division Regulation Of Mitotic Metaphase/anaphase Transition Regulation Of Protein Localization To Plasma Membrane Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Regulation Of DNA-templated Transcription In Response To Stress Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition TRIF-dependent Toll-like Receptor Signaling Pathway Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Negative Regulation Of Ubiquitin-protein Transferase Activity Negative Regulation Of Proteasomal Protein Catabolic Process MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Intracellular Steroid Hormone Receptor Signaling Pathway Prostate Gland Development Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity Negative Regulation Of Biosynthetic Process Negative Regulation Of Cellular Protein Catabolic Process Positive Regulation Of Ligase Activity BMP Signaling Pathway
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