HSD3B7 and PYGL

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		HSD3B7	PYGL
Gene Name		hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7	phosphorylase, glycogen, liver
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cellular_component Endoplasmic Reticulum Membrane Integral Component Of Membrane	Cytoplasm Cytosol Plasma Membrane Extracellular Vesicular Exosome
	Molecular Function	3-beta-hydroxy-delta5-steroid Dehydrogenase Activity Cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase Activity	Purine Nucleobase Binding ATP Binding Glucose Binding Drug Binding Glycogen Phosphorylase Activity AMP Binding Vitamin Binding Pyridoxal Phosphate Binding Bile Acid Binding Protein Homodimerization Activity
	Biological Process	Bile Acid Biosynthetic Process Bile Acid Metabolic Process Small Molecule Metabolic Process Oxidation-reduction Process	Carbohydrate Metabolic Process Glycogen Metabolic Process Glycogen Catabolic Process Glucose Metabolic Process 5-phosphoribose 1-diphosphate Biosynthetic Process Pathogenesis Glucose Homeostasis Small Molecule Metabolic Process Necroptotic Process
Pathways		Bile acid and bile salt metabolism Synthesis of bile acids and bile salts via 24-hydroxycholesterol Synthesis of bile acids and bile salts via 27-hydroxycholesterol Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol Metabolism of lipids and lipoproteins Synthesis of bile acids and bile salts	Glucose metabolism Glycogen breakdown (glycogenolysis) Myoclonic epilepsy of Lafora Glycogen storage diseases Metabolism of carbohydrates
Drugs			Pyridoxal Phosphate Adenosine monophosphate 7,9-Dihydro-1h-Purine-2,6,8(3h)-Trione CP-526423 1-N-Acetyl-Beta-D-Glucosamine Beta-D-Glucose 5-Chloro-1h-Indole-2-Carboxylic Acid{[Cyclopentyl-(2-Hydroxy-Ethyl)-Carbamoyl]-Methyl}-Amide Cp403700, (S)-1-{2-[(5-Chloro-1h-Indole-2-Carbonyl)-Amino]-3-Phenyl-Propionyl}-Azetidine-3-Carboxylate Phosphonoserine 5-chloro-N-{4-[(1R)-1,2-dihydroxyethyl]phenyl}-1H-indole-2-carboxamide 4-[3-(2-Chloro-4,5-difluoro-benzoyl)ureido]-3-trifluoromethoxybenzoic acid 1-{2-[3-(2-Chloro-4,5-difluoro-benzoyl)-ureido]-4-fluoro-phenyl}-piperidine-4-carboxylic acid N-(2-CHLORO-4-FLUOROBENZOYL)-N\'-(5-HYDROXY-2-METHOXYPHENYL)UREA
Diseases
GWAS			Acute lymphoblastic leukemia (childhood) ( 23007406)
Protein-Protein Interactions		11 interactors: DAPP1 ICAM1 KRTAP10-1 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP4-2 NOTCH2NL PYGL SPRY2	4 interactors: BAG1 HSD3B7 IDH2 PYGB
Entrez ID		80270	5836
HPRD ID		09680	01987
Ensembl ID		ENSG00000099377	ENSG00000100504
Uniprot IDs		Q9H2F3	P06737
PDB IDs			1EM6 1EXV 1FA9 1FC0 1L5Q 1L5R 1L5S 1L7X 1XOI 2ATI 2QLL 2ZB2 3CEH 3CEJ 3CEM 3DD1 3DDS 3DDW
Enriched GO Terms of Interacting Partners?		Response To Sulfur Dioxide Positive Regulation Of ERK1 And ERK2 Cascade T Cell Activation Via T Cell Receptor Contact With Antigen Bound To MHC Molecule On Antigen Presenting Cell Sensory Perception Of Sound Sensory Perception Of Mechanical Stimulus Regulation Of ERK1 And ERK2 Cascade Glucose Homeostasis 5-phosphoribose 1-diphosphate Biosynthetic Process Receptor-mediated Virion Attachment To Host Cell T Cell Antigen Processing And Presentation Membrane To Membrane Docking Positive Regulation Of Cellular Extravasation Establishment Of Sertoli Cell Barrier Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway Virion Attachment To Host Cell Lung Growth Acute Inflammatory Response To Antigenic Stimulus Regulation Of Neurotrophin TRK Receptor Signaling Pathway Adhesion Of Symbiont To Host Bud Elongation Involved In Lung Branching Regulation Of Cellular Amino Acid Metabolic Process Cell Adhesion Mediated By Integrin Positive Regulation Of MAPK Cascade Glycogen Catabolic Process Negative Regulation Of Peptidyl-threonine Phosphorylation Regulation Of Ruffle Assembly Negative Regulation Of Ras GTPase Activity Regulation Of Cellular Ketone Metabolic Process Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Polysaccharide Catabolic Process Sertoli Cell Development Response To Copper Ion Regulation Of Ras GTPase Activity	Glyoxylate Cycle Negative Regulation Of Motor Neuron Apoptotic Process Cellular Carbohydrate Metabolic Process Chaperone Cofactor-dependent Protein Refolding Energy Derivation By Oxidation Of Organic Compounds Oxidation-reduction Process Isocitrate Metabolic Process Glyoxylate Metabolic Process Generation Of Precursor Metabolites And Energy 2-oxoglutarate Metabolic Process Glycogen Catabolic Process Monocarboxylic Acid Metabolic Process Protein Refolding Small Molecule Metabolic Process Polysaccharide Catabolic Process Bile Acid Biosynthetic Process Cellular Carbohydrate Catabolic Process Bile Acid Metabolic Process Tricarboxylic Acid Cycle Citrate Metabolic Process Tricarboxylic Acid Metabolic Process Glycogen Metabolic Process Aerobic Respiration Positive Regulation Of Neuron Apoptotic Process Chaperone-mediated Protein Folding Carboxylic Acid Metabolic Process Carbohydrate Metabolic Process Protein Localization To Mitochondrion Positive Regulation Of Neuron Death Cellular Aldehyde Metabolic Process Organic Acid Metabolic Process
Tagcloud ?			coater crystallized degassing depositing diaphragm evacuated evaporable evaporated evaporation film glu glutamic handmade intramolecular lactamization molten particulates periodic preserving pyroglutamic quartz racemization resonator simply soldering spacing thin vacuum versatile
Tagcloud (Difference) ?			coater crystallized degassing depositing diaphragm evacuated evaporable evaporated evaporation film glu glutamic handmade intramolecular lactamization molten particulates periodic preserving pyroglutamic quartz racemization resonator simply soldering spacing thin vacuum versatile
Tagcloud (Intersection) ?