HSD3B7

Gene Name		hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cellular_component Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	3-beta-hydroxy-delta5-steroid Dehydrogenase Activity Cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase Activity
	Biological Process	Bile Acid Biosynthetic Process Bile Acid Metabolic Process Small Molecule Metabolic Process Oxidation-reduction Process
Pathways		Bile acid and bile salt metabolism Synthesis of bile acids and bile salts via 24-hydroxycholesterol Synthesis of bile acids and bile salts via 27-hydroxycholesterol Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol Metabolism of lipids and lipoproteins Synthesis of bile acids and bile salts
Drugs
Diseases
GWAS
Protein-protein Interactions		11 interactors: DAPP1 ICAM1 KRTAP10-1 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP4-2 NOTCH2NL PYGL SPRY2
Entrez ID		80270
HPRD ID		09680
Ensembl ID		ENSG00000099377
Uniprot IDs		Q9H2F3
PDB IDs
Enriched GO Terms of Interacting Partners?		Response To Sulfur Dioxide Positive Regulation Of ERK1 And ERK2 Cascade T Cell Activation Via T Cell Receptor Contact With Antigen Bound To MHC Molecule On Antigen Presenting Cell Sensory Perception Of Sound Sensory Perception Of Mechanical Stimulus Regulation Of ERK1 And ERK2 Cascade Glucose Homeostasis 5-phosphoribose 1-diphosphate Biosynthetic Process Receptor-mediated Virion Attachment To Host Cell T Cell Antigen Processing And Presentation Membrane To Membrane Docking Positive Regulation Of Cellular Extravasation Establishment Of Sertoli Cell Barrier Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway Virion Attachment To Host Cell Lung Growth Acute Inflammatory Response To Antigenic Stimulus Regulation Of Neurotrophin TRK Receptor Signaling Pathway Adhesion Of Symbiont To Host Bud Elongation Involved In Lung Branching Regulation Of Cellular Amino Acid Metabolic Process Cell Adhesion Mediated By Integrin Positive Regulation Of MAPK Cascade Glycogen Catabolic Process Negative Regulation Of Peptidyl-threonine Phosphorylation Regulation Of Ruffle Assembly Negative Regulation Of Ras GTPase Activity Regulation Of Cellular Ketone Metabolic Process Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Polysaccharide Catabolic Process Sertoli Cell Development Response To Copper Ion Regulation Of Ras GTPase Activity
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