SLC25A46 and FUNDC1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		SLC25A46	FUNDC1
Description		solute carrier family 25 member 46	FUN14 domain containing 1
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Outer Membrane Membrane	Mitochondrion Mitochondrial Outer Membrane Membrane
	Molecular Function	Protein Binding Protein-containing Complex Binding	Protein Binding
	Biological Process	Mitochondrial Fission Autophagy Of Mitochondrion Mitochondrial Transport Mitochondrion Organization Synapse Assembly Respiratory Chain Complex IV Assembly Dendrite Development Optic Nerve Development Cerebellar Purkinje Cell Differentiation Myelination In Peripheral Nervous System Locomotion Involved In Locomotory Behavior Cristae Formation Peripheral Nervous System Neuron Axonogenesis Establishment Of Localization In Cell Phospholipid Homeostasis Axon Development Protein-containing Complex Assembly Mitochondrial Membrane Fission	Autophagy Of Mitochondrion Mitophagy Response To Hypoxia Autophagy Mitochondrial Fusion
Pathways			Receptor Mediated Mitophagy
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever and/or eczema) (age of onset) ( 32603359) Allergic disease (asthma, hay fever and/or eczema) (multivariate analysis) ( 32603359) Allergic disease (asthma, hay fever or eczema) ( 29083406 29785011) Allergic sensitization ( 23817571) Asthma ( 34103634 31959851 31619474 30929738 29273806 27182965) Asthma (adult onset) ( 30929738 31036433) Asthma (age of onset) ( 31036433) Asthma (childhood onset) ( 30929738 31036433) Asthma and hay fever ( 24388013) Asthma onset (childhood vs adult) ( 30929738) Asthma or allergic disease (pleiotropy) ( 29785011) Cardiac structure and function ( 19584346) Medication use (adrenergics, inhalants) ( 31015401) Medication use (antihistamines for systemic use) ( 31015401) Thrombin-activatable fibrinolysis inhibitor levels ( 29378355) Uterine fibroid size (maximum volume) ( 30196971)	Facial morphology (factor 22) ( 28441456) Personality dimensions ( 18957941)
Interacting Genes		16 interacting genes: AQP6 FHL3 FUNDC1 HSD17B11 HSD17B13 LEPROTL1 ODF4 REEP2 REEP4 SLC10A1 SLC10A6 SLC66A2 SLC71A2 SLC7A8 SPCS1 VMA21	15 interacting genes: CTBP1 CTBP2 EHHADH GABARAPL1 GABARAPL2 MAP1LC3A MAP1LC3B MARCHF5 MTERF3 SENP2 SH3GLB1 SLC25A46 SNX1 TUFM YES1
Entrez ID		91137	139341
HPRD ID		14283	06658
Ensembl ID		ENSG00000164209	ENSG00000069509
Uniprot IDs		B4DY98 Q96AG3	Q8IVP5
PDB IDs		8TMU	2N9X 5GMV
Enriched GO Terms of Interacting Partners?		Steroid Dehydrogenase Activity Bile Acid:sodium Symporter Activity Bile Acid And Bile Salt Transport Estradiol 17-beta-dehydrogenase [NAD(P)+] Activity Endoplasmic Reticulum Tubular Network Endoplasmic Reticulum Tubular Network Organization Nitrate Transmembrane Transporter Activity Membrane Taste Receptor Binding Sodium-dependent Organic Anion Transmembrane Transporter Activity Sodium-dependent Organic Anion Transport PH-gated Chloride Channel Activity Nitrate Transmembrane Transport Carboxylic Acid Transport Organic Acid Transport Endoplasmic Reticulum Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor Endoplasmic Reticulum Organization Cytoplasmic Microtubule Carbon Dioxide Transmembrane Transporter Activity Transmembrane Transport Carbon Dioxide Transmembrane Transport Lipid Transport Symporter Activity Organic Anion Transport Tryptophan Transport L-alanine Transmembrane Transport L-leucine Transmembrane Transporter Activity L-leucine Import Across Plasma Membrane L-alanine Import Across Plasma Membrane Valine Transport Signal Peptidase Complex Androgen Catabolic Process Lipid Droplet Protein Transport Into Membrane Raft Sensory Perception Of Sweet Taste Sensory Perception Of Bitter Taste Vacuolar Proton-transporting V-type ATPase Complex Assembly Proline Transmembrane Transport Glycine Transmembrane Transporter Activity L-alanine Transmembrane Transporter Activity Monocarboxylic Acid Transport Toxin Transmembrane Transporter Activity Thyroid Hormone Transmembrane Transporter Activity Proton-transporting V-type ATPase Complex Assembly Monoatomic Anion Channel Activity Ammonium Channel Activity Renal Water Transport Bile Acid Transmembrane Transporter Activity L-alanine Transport	Cellular Response To Nitrogen Starvation Phosphatidylethanolamine Binding Autophagosome Membrane Autophagy Of Mitochondrion Autophagosome Maturation Autophagy Mitophagy Cellular Response To Starvation Mitochondrial Outer Membrane Autophagosome Response To Starvation Autophagosome Assembly Autophagosome Organization Cellular Response To Nutrient Levels Phospholipid Binding Protein-containing Complex Disassembly Macroautophagy Vacuole Organization Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor Response To Nutrient Levels White Fat Cell Differentiation GABA Receptor Binding Ubiquitin Protein Ligase Binding Viral Genome Replication Fat Cell Differentiation Mitochondrion Organelle Assembly NAD Binding Cytoplasmic Vesicle Beta-tubulin Binding Transcription Coregulator Binding Catabolic Process Membrane Fission Organelle Membrane Protein-containing Complex Organization Transcription Corepressor Binding Protein Localization To Vacuolar Membrane Microtubule Binding Cellular Response To Amino Acid Starvation Transcription Repressor Complex Response To Amino Acid Starvation Long-chain (3S)-3-hydroxyacyl-CoA Dehydrogenase (NAD+) Activity Intramolecular Oxidoreductase Activity, Transposing C=C Bonds Mitochondrial Membrane Fission Cellular Component Assembly Positive Regulation Of Membrane Tubulation Microtubule Delta(3)-delta(2)-enoyl-CoA Isomerase Activity Retromer, Tubulation Complex Leptin Receptor Binding
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