NR4A3 and TRIM28

Number of citations of the paper that reports this interaction (PMID 19321449)
12

Data Source:
BioGRID (pull down)

		NR4A3	TRIM28
Gene Name		nuclear receptor subfamily 4, group A, member 3	tripartite motif containing 28
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Transcription Factor Complex	Nucleus Nucleoplasm Nuclear Euchromatin Nuclear Heterochromatin RNA Polymerase II Transcription Factor Complex
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription DNA Binding Steroid Hormone Receptor Activity Thyroid Hormone Receptor Activity Protein Binding Zinc Ion Binding Sequence-specific DNA Binding	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Coactivator Activity Transcription Corepressor Activity Protein Kinase Activity Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Ligase Activity Ubiquitin Protein Ligase Binding Krueppel-associated Box Domain Binding Sequence-specific DNA Binding Poly(A) RNA Binding Chromo Shadow Domain Binding
	Biological Process	Mesoderm Formation Transcription Initiation From RNA Polymerase II Promoter Axon Guidance Biological_process Gene Expression Hippocampus Development Intracellular Receptor Signaling Pathway Adult Behavior Organ Regeneration Response To Hydrogen Peroxide Steroid Hormone Mediated Signaling Pathway Response To Peptide Hormone Negative Regulation Of Neuron Apoptotic Process Positive Regulation Of Cell Cycle Positive Regulation Of Transcription From RNA Polymerase II Promoter Semicircular Canal Morphogenesis Neuromuscular Process Controlling Balance Vestibular Reflex Positive Regulation Of Leukocyte Apoptotic Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Epithelial To Mesenchymal Transition DNA Repair Transcription Initiation From RNA Polymerase II Promoter Embryo Implantation Gene Expression Protein Ubiquitination Protein Sumoylation Positive Regulation Of Transcription Factor Import Into Nucleus DNA Methylation Involved In Embryo Development Innate Immune Response Positive Regulation Of DNA Repair Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Protein Autophosphorylation Protein Oligomerization Convergent Extension Involved In Axis Elongation Embryonic Placenta Morphogenesis Negative Regulation Of DNA Demethylation Negative Regulation Of Viral Release From Host Cell Regulation Of Genetic Imprinting
Pathways			Generic Transcription Pathway
Drugs
Diseases
GWAS		Dental caries ( 23064961)
Protein-Protein Interactions		5 interactors: COPS5 RPS6KA1 SIX3 TRIM28 VHL	62 interactors: CBX1 CBX3 CBX5 CDC34 CDCA4 CEBPB CHAF1A CHD3 ESR1 FES HDAC10 HTRA2 IRF1 IRF7 LYN MAGEA2 MAGEA2B MAGEA3 MAGEA6 MAGED1 MYB NDNL2 NR3C1 NR4A1 NR4A3 PFDN5 PPP4C RNF4 SENP7 SERTAD1 SERTAD2 SETDB1 SIN3A SKI SMARCAD1 SPG7 STAT3 TRIM24 UBE2C UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2E2 UBE2H UBE2I UBE2L3 UBE2N UBE2U VHL VIM YWHAQ ZNF10 ZNF133 ZNF140 ZNF197 ZNF354A ZNF382 ZNF420 ZNF496 ZNF689 ZNF74
Entrez ID		8013	10155
HPRD ID		02766	03445
Ensembl ID		ENSG00000119508	ENSG00000130726
Uniprot IDs		Q92570	Q13263
PDB IDs			1FP0 2RO1 2YVR
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Metabolic Process Regulation Of DNA-templated Transcription In Response To Stress Positive Regulation Of Metabolic Process Regulation Of Transcription, DNA-templated Neuroblast Migration Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Negative Regulation Of Cellular Metabolic Process Regulation Of Gene Expression Negative Regulation Of DNA Demethylation Optic Vesicle Morphogenesis Positive Regulation Of Hepatic Stellate Cell Activation Regulation Of Nitrogen Compound Metabolic Process Transcription From RNA Polymerase II Promoter Anatomical Structure Morphogenesis Regulation Of Neural Retina Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Lens Fiber Cell Apoptotic Process Neuroblast Differentiation Exosomal Secretion Cell Morphogenesis Negative Regulation Of Transcription, DNA-templated Proximal/distal Axis Specification Convergent Extension Involved In Axis Elongation Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Genetic Imprinting DNA Methylation Involved In Embryo Development Cellular Protein Modification Process Negative Regulation Of Gene Expression Stem Cell Differentiation Negative Regulation Of Biosynthetic Process Forebrain Anterior/posterior Pattern Specification Cullin Deneddylation Forebrain Dorsal/ventral Pattern Formation Lens Induction In Camera-type Eye Protein Deneddylation Cellular Response To Stress Regulation Of Cell Differentiation Convergent Extension Telencephalon Regionalization Negative Regulation Of Viral Release From Host Cell Regulation Of Metabolic Process	Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of RNA Metabolic Process Transcription, DNA-templated Regulation Of Gene Expression RNA Biosynthetic Process Regulation Of Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Gene Expression Protein K48-linked Ubiquitination RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Macromolecule Biosynthetic Process Gene Expression Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process Protein Polyubiquitination Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Protein Catabolic Process Cellular Metabolic Process Regulation Of Cellular Process Cellular Protein Catabolic Process Positive Regulation Of Metabolic Process Protein Ubiquitination Biosynthetic Process Protein Modification By Small Protein Conjugation Protein K11-linked Ubiquitination Cellular Macromolecule Catabolic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Gene Expression Positive Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Ligase Activity Positive Regulation Of Protein Ubiquitination Positive Regulation Of Macromolecule Biosynthetic Process Transcription From RNA Polymerase II Promoter Regulation Of Ubiquitin-protein Transferase Activity Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Biosynthetic Process
Tagcloud ?		annotation ccaat cebpd crosstalk cytoscape degs dissect downloaded encyclopedia fbj fosb gse14245 gse21654 gse32676 hub klf5 kruppel kyoto logarithm logfc omnibus ontology pentraxin ppi ptx3 sfn stratifin tfs trasfac	accumulates aging becoming damaged depletion genomes il6 il8 ink4a insults kap1 knocked krab limits mediating mixture ois oncogene partially pathologies prevented profound reinforcing sasp secrete secretory senescence termed undergo
Tagcloud (Difference) ?		annotation ccaat cebpd crosstalk cytoscape degs dissect downloaded encyclopedia fbj fosb gse14245 gse21654 gse32676 hub klf5 kruppel kyoto logarithm logfc omnibus ontology pentraxin ppi ptx3 sfn stratifin tfs trasfac	accumulates aging becoming damaged depletion genomes il6 il8 ink4a insults kap1 knocked krab limits mediating mixture ois oncogene partially pathologies prevented profound reinforcing sasp secrete secretory senescence termed undergo
Tagcloud (Intersection) ?