DSN1 and NSL1

Number of citations of the paper that reports this interaction (PubMedID 15502821)
0

Data Source:
HPRD (in vitro)

		DSN1	NSL1
Description		DSN1 component of MIS12 kinetochore complex	NSL1 component of MIS12 kinetochore complex
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GO Annotations	Cellular Component	MIS12/MIND Type Complex Chromosome, Centromeric Region Kinetochore Spindle Pole Outer Kinetochore Fibrillar Center Extracellular Region Nucleus Nucleoplasm Chromosome Nucleolus Cytosol Nuclear Body Azurophil Granule Lumen	MIS12/MIND Type Complex Chromosome, Centromeric Region Kinetochore Spindle Pole Outer Kinetochore Nucleus Chromosome Cytosol Nuclear Speck
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Chromosome Segregation Attachment Of Spindle Microtubules To Kinetochore Skeletal Muscle Satellite Cell Proliferation Cell Division	Mitotic Sister Chromatid Segregation Chromosome Segregation Attachment Of Spindle Microtubules To Kinetochore Cell Division
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Neutrophil degranulation Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation	Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Factor VII activity ( 30642921) Hallux valgus ( 32131869)
Interacting Genes		12 interacting genes: AIMP2 APP CBX3 CBX5 HGS KNL1 MIS12 NSL1 PIK3R3 PMF1 SUGT1 ZWINT	7 interacting genes: CBX5 DSN1 G6PC1 HSP90AA1 LRRK2 MIS12 SUGT1
Entrez ID		79980	25936
HPRD ID		16455	12378
Ensembl ID		ENSG00000149636	ENSG00000117697
Uniprot IDs		A8K3X3 Q9H410	Q53FM2 Q5SY74 Q96IY1
PDB IDs		5LSI 5LSJ 5LSK 8PPR 8Q5H	4NF9 5LSI 5LSJ 5LSK 8PPR 8Q5H
Enriched GO Terms of Interacting Partners?		Outer Kinetochore Kinetochore Chromosome, Centromeric Region MIS12/MIND Type Complex Mitotic Sister Chromatid Segregation Attachment Of Spindle Microtubules To Kinetochore Sister Chromatid Segregation Chromosome Segregation Nuclear Chromosome Segregation Knl1/Spc105 Complex Regulation Of Meiosis I Spindle Assembly Checkpoint Homologous Chromosome Orientation In Meiotic Metaphase I Chromosome Organization Chromosome Regulation Of Meiosis I Cell Division Kinetochore Assembly Kinetochore Organization Spindle Pole Pericentric Heterochromatin Regulation Of Meiotic Nuclear Division Cytosol Site Of DNA Damage Heterochromatin Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Meiosis I Spindle Assembly Checkpoint Epigenetic Regulation Of Gene Expression Regulation Of Mitotic Sister Chromatid Separation Regulation Of Meiotic Cell Cycle Positive Regulation Of Neuron Apoptotic Process Organelle Assembly Regulation Of Chromosome Separation Acetylcholine Receptor Activator Activity Lipoprotein Particle Positive Regulation Of Protein Import Chromosome Localization Nucleus PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization	Kinetochore MIS12/MIND Type Complex Skeletal Muscle Satellite Cell Proliferation Skeletal Muscle Cell Proliferation Kinetochore Assembly Kinetochore Organization Chromosome, Centromeric Region Outer Kinetochore Attachment Of Spindle Microtubules To Kinetochore Protein Localization To Mitochondrion Muscle Cell Proliferation CTP Binding Chromosome Organization DATP Binding Regulation Of Protein Stability Cellular Response To Curcumin Caveola Neck GTP-dependent Protein Kinase Activity Wnt Signalosome Assembly Neurofibrillary Tangle Assembly UTP Binding Protein-containing Complex Assembly Sulfonylurea Receptor Binding Negative Regulation Of Late Endosome To Lysosome Transport Amphisome Peroxidase Inhibitor Activity Negative Regulation Of Protein Processing Involved In Protein Targeting To Mitochondrion Beta-catenin Destruction Complex Binding Glucose-6-phosphatase Activity Rho GDP-dissociation Inhibitor Binding Histone Deacetylase Binding Positive Regulation Of Protein Autoubiquitination Response To Curcumin Transmembrane Transporter Binding Protein-containing Complex Organization Chromosome Segregation Response To Resveratrol Glucose-6-phosphate Transport Sperm Mitochondrial Sheath Chromosome Spindle Pole Cytoplasmic Side Of Mitochondrial Outer Membrane Positive Regulation Of Dopamine Receptor Signaling Pathway Multivesicular Body, Internal Vesicle Regulation Of CAMKK-AMPK Signaling Cascade Regulation Of Branching Morphogenesis Of A Nerve Regulation Of Synaptic Vesicle Transport Telomerase Holoenzyme Complex Assembly Regulation Of Protein Autoubiquitination Positive Regulation Of Synaptic Vesicle Endocytosis
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