PDZD7 and CEP76

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PDZD7	CEP76
Description		PDZ domain containing 7	centrosomal protein 76
Image			No pdb structure
GO Annotations	Cellular Component	Stereocilia Ankle Link Stereocilia Ankle Link Complex Extracellular Space Nucleus Nucleoplasm Plasma Membrane Cilium Stereocilium Stereocilium Tip Ciliary Basal Body Cell Projection Organelle Plasma Membrane Bounded Cell Projection USH2 Complex	Cytoplasm Centrosome Centriole Cytosol Cytoskeleton Protein-containing Complex
	Molecular Function	Protein Binding Identical Protein Binding	Protein Binding
	Biological Process	Sensory Perception Of Sound Establishment Of Protein Localization Detection Of Mechanical Stimulus Involved In Sensory Perception Of Sound Establishment Of Localization In Cell Auditory Receptor Cell Stereocilium Organization Inner Ear Receptor Cell Differentiation Auditory Receptor Cell Development	Regulation Of Centriole Replication
Pathways			Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs
Diseases
GWAS		Regular attendance at a pub or social club ( 29970889)
Interacting Genes		2 interacting genes: CEP76 RPS6KA1	105 interacting genes: AKAP7 AKT1 ANKRD36 ASH2L BANP C22orf39 CABP5 CACNB3 CAPN3 CAVIN3 CCDC92 CCNK CDK18 CENPI CIRSR COIL CRYBA4 CSNK1G1 CUTC CWF19L2 DCTD DDX6 DEAF1 DMTN DVL3 DZIP1L EAF1 EIF1AD EP400P1 ERCC3 FAM90A1 GDAP2 GFAP GORASP2 HACL2 HSF2 HSPB7 IQUB KDM1A KDM4D KIAA1143 KIFBP KLHDC4 L3MBTL2 LATS1 LNX1 MAGEA11 MBD3 MFAP1 MISP MLH1 MYOZ1 NEK6 NFYC NHLRC2 NME5 PAICS PARD6B PATZ1 PDGFRB PDRG1 PDZD4 PDZD7 PIN1 PKP1 PLA2G6 PLCB1 POM121 RADIL RALGPS1 RBM41 RIPPLY3 RNF128 RPL9 SALL2 SCNM1 SH2D4A SINHCAF SMG9 SPG21 STK26 SUOX TBC1D27P TCEA2 TCEANC TCF19 TFAP2D THRA TOB2 TSPOAP1 TSSC4 TTC21A TTLL10 TUFT1 TXNDC9 VEZF1 WDFY3 YY1 ZBTB24 ZBTB4 ZMAT2 ZNF185 ZNF653 ZNF76 ZNF85
Entrez ID		79955	79959
HPRD ID		15114	12694
Ensembl ID		ENSG00000186862	ENSG00000101624
Uniprot IDs		A0A2R8Y892 A0A2R8YFN1 Q9H5P4	B4DP81 Q8TAP6
PDB IDs		2EEH 7PC5
Enriched GO Terms of Interacting Partners?		Hepatocyte Proliferation Positive Regulation Of Hepatic Stellate Cell Activation Ribosomal Protein S6 Kinase Activity Protein Serine/threonine/tyrosine Kinase Activity Regulation Of Translation In Response To Stress Regulation Of Centriole Replication	Protein Binding Nucleus
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