RSPH3

Description		radial spoke head 3
Image
GO Annotations	Cellular Component	Radial Spoke Head Cytoplasm Cytoskeleton Cilium Motile Cilium Cell Projection 9+2 Motile Cilium
	Molecular Function	Protein Binding
	Biological Process
Pathways
Drugs
Diseases
GWAS		Attention deficit hyperactivity disorder ( 32279069) Bladder cancer (smoking interaction) ( 24662972) Celiac disease ( 25920553) Lipoprotein (a) levels ( 26377243) Prepulse inhibition of the startle response ( 31596458) Systemic lupus erythematosus ( 28714469)
Novel Interacting Genes		1 novel interacting genes: TAGAP
Interacting Genes		8 interacting genes: APP DPY30 FAM124B HSPB1 MLH1 PRKAR1A ROPN1L RSPH14
Entrez ID		83861
HPRD ID		15279
Ensembl ID		ENSG00000130363
Uniprot IDs		Q86UC2
PDB IDs		8J07
Enriched GO Terms of Interacting Partners?		Radial Spoke Positive Regulation Of Gene Expression, Epigenetic Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Microtubule-based Transport Amylin Binding Positive Regulation Of Toll Signaling Pathway Regulation Of CAMP/PKA Signal Transduction Positive Regulation Of Interleukin-1 Beta Production Microtubule-based Process Negative Regulation Of Protein Kinase C Signaling Late Recombination Nodule Meiotic Metaphase I Homologous Chromosome Alignment Acetylcholine Receptor Activator Activity PTB Domain Binding Positive Regulation Of Interleukin-1 Production Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Axo-dendritic Transport Regulation Of Interleukin-1 Production Positive Regulation Of Tumor Necrosis Factor Production Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Positive Regulation Of Tumor Necrosis Factor Superfamily Cytokine Production Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Microtubule-based Movement Regulation Of Interleukin-1 Beta Production Protein Kinase C Inhibitor Activity Meiotic Spindle Midzone Assembly Meiotic Metaphase Chromosome Alignment Male Meiosis Chromosome Segregation MutLalpha Complex Chiasma Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Gene Expression Positive Regulation Of Chemotaxis Positive Regulation Of Amyloid Fibril Formation Cellular Response To Norepinephrine Stimulus Growth Factor Receptor Binding Main Axon Astrocyte Activation Involved In Immune Response
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