RSPH3 and ROPN1L

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		RSPH3	ROPN1L
Description		radial spoke head 3	rhophilin associated tail protein 1 like
Image
GO Annotations	Cellular Component	Radial Spoke Head Cytoplasm Cytoskeleton Cilium Motile Cilium Cell Projection 9+2 Motile Cilium	Radial Spoke Extracellular Region Nucleoplasm Cytoplasm Cilium Motile Cilium Cell Projection
	Molecular Function	Protein Binding	Protein Binding Identical Protein Binding
	Biological Process		Cilium Movement Epithelial Cilium Movement Involved In Extracellular Fluid Movement Flagellated Sperm Motility Sperm Capacitation
Pathways
Drugs
Diseases
GWAS		Attention deficit hyperactivity disorder ( 32279069) Bladder cancer (smoking interaction) ( 24662972) Celiac disease ( 25920553) Lipoprotein (a) levels ( 26377243) Prepulse inhibition of the startle response ( 31596458) Systemic lupus erythematosus ( 28714469)	Body mass index ( 22446040) Breast cancer ( 21424380) Coronary artery disease in type 1 diabetes ( 29695241) Dermatomyositis or juvenile dermatomyositis ( 26362759) Mean arterial pressure ( 27618448) Triglyceride levels ( 31170924)
Interacting Genes		8 interacting genes: APP DPY30 FAM124B HSPB1 MLH1 PRKAR1A ROPN1L RSPH14	7 interacting genes: AKAP14 AKAP3 AKAP5 AKAP7 APP BEX2 RSPH3
Entrez ID		83861	83853
HPRD ID		15279	17986
Ensembl ID		ENSG00000130363	ENSG00000145491
Uniprot IDs		Q86UC2	Q96C74
PDB IDs		8J07	8J07
Enriched GO Terms of Interacting Partners?		Radial Spoke Positive Regulation Of Gene Expression, Epigenetic Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Microtubule-based Transport Amylin Binding Positive Regulation Of Toll Signaling Pathway Regulation Of CAMP/PKA Signal Transduction Positive Regulation Of Interleukin-1 Beta Production Microtubule-based Process Negative Regulation Of Protein Kinase C Signaling Late Recombination Nodule Meiotic Metaphase I Homologous Chromosome Alignment Acetylcholine Receptor Activator Activity PTB Domain Binding Positive Regulation Of Interleukin-1 Production Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Axo-dendritic Transport Regulation Of Interleukin-1 Production Positive Regulation Of Tumor Necrosis Factor Production Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Positive Regulation Of Tumor Necrosis Factor Superfamily Cytokine Production Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Microtubule-based Movement Regulation Of Interleukin-1 Beta Production Protein Kinase C Inhibitor Activity Meiotic Spindle Midzone Assembly Meiotic Metaphase Chromosome Alignment Male Meiosis Chromosome Segregation MutLalpha Complex Chiasma Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Gene Expression Positive Regulation Of Chemotaxis Positive Regulation Of Amyloid Fibril Formation Cellular Response To Norepinephrine Stimulus Growth Factor Receptor Binding Main Axon Astrocyte Activation Involved In Immune Response	Protein Kinase A Binding Protein Kinase A Regulatory Subunit Binding Positive Regulation Of Long-term Synaptic Potentiation Dendrite Membrane Regulation Of Long-term Synaptic Potentiation Regulation Of Monoatomic Cation Transmembrane Transport Regulation Of Monoatomic Ion Transmembrane Transport Positive Regulation Of Calcium-mediated Signaling Cellular Response To CAMP Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Monoatomic Ion Transport Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Regulation Of Metal Ion Transport Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Response To CAMP Acetylcholine Receptor Activator Activity PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Modulation Of Chemical Synaptic Transmission Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Regulation Of Calcium-mediated Signaling Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Cell Projection Positive Regulation Of Cation Transmembrane Transport Positive Regulation Of Monoatomic Ion Transmembrane Transport Positive Regulation Of Endosome To Plasma Membrane Protein Transport Response To Purine-containing Compound Regulation Of Calcium Ion Transmembrane Transport Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Norepinephrine Stimulus Positive Regulation Of Synaptic Transmission Astrocyte Activation Involved In Immune Response Dendritic Spine Low-density Lipoprotein Particle Mediated Signaling Intermediate-density Lipoprotein Particle Calcium-mediated Signaling Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Growth Factor Receptor Binding
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