SNIP1 and GMEB1

Number of citations of the paper that reports this interaction (PubMedID 15231748)
54

Data Source:
HPRD (two hybrid)

		SNIP1	GMEB1
Description		Smad nuclear interacting protein 1	glucocorticoid modulatory element binding protein 1
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex U2 SnRNP Cytosol U2-type Precatalytic Spliceosome	Chromatin Nucleus Nucleoplasm Cytoplasm
	Molecular Function	RNA Binding MRNA Binding Protein Binding Transcription Regulator Inhibitor Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Identical Protein Binding Sequence-specific DNA Binding Metal Ion Binding Hsp27 Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Regulation Of Gene Expression Regulatory NcRNA-mediated Gene Silencing MiRNA Processing Negative Regulation Of Canonical NF-kappaB Signal Transduction U2-type Prespliceosome Assembly	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II
Pathways		mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Axial length ( 24144296) Eyebrow thickness ( 26926045)	Basophil count ( 32888494)
Interacting Genes		47 interacting genes: CDK6 CREBBP DVL2 DVL3 EIF3C EP300 ESRRG FAF1 GMEB1 GYS1 HIPK1 HIPK3 KRTAP10-6 MAX MYC PHF19 PIAS1 PIAS2 PIAS3 PIAS4 POU2F1 PRPF3 PRPF40A RELA SETDB1 SF3B1 SMAD1 SMAD2 SMAD4 SON SP100 SPANXN2 SRPK2 SRRM4 STK3 TDG TNIP1 TOPORS TSPYL2 TTC14 UBE2I ZBTB9 ZCCHC10 ZCCHC7 ZMYM2 ZMYM5 ZNF451	16 interacting genes: ATF7IP CASP8 CASP9 CREBBP DNMT3L GMEB2 MX1 NCOA2 RAD51 SMAD1 SMAD3 SNIP1 SPOP TRIM55 TRIM63 UBE2I
Entrez ID		79753	10691
HPRD ID		06999	16059
Ensembl ID		ENSG00000163877	ENSG00000162419
Uniprot IDs		B1AK66 Q8TAD8	B1AT47 B2RCN8 Q9Y692
PDB IDs		5Z56 5Z57 5Z58 6FF7 7ABG 7ABH 7ABI 7DVQ 8I0P 8I0R	1OQJ
Enriched GO Terms of Interacting Partners?		Regulation Of Nucleobase-containing Compound Metabolic Process PML Body Chromatin Regulation Of RNA Metabolic Process Regulation Of Transcription By RNA Polymerase II Regulation Of Macromolecule Metabolic Process Nucleoplasm Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Nucleus Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Metabolic Process Regulation Of Primary Metabolic Process SUMO Transferase Activity Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of RNA Metabolic Process Protein Sumoylation SUMO Ligase Activity Positive Regulation Of RNA Metabolic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of DNA-templated Transcription Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Transcription Coregulator Activity Positive Regulation Of Transcription By RNA Polymerase II DNA Binding Positive Regulation Of Biosynthetic Process SMAD Protein Signal Transduction Positive Regulation Of MiRNA Transcription Negative Regulation Of Macromolecule Metabolic Process Nucleic Acid Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Metabolic Process Negative Regulation Of Biosynthetic Process Positive Regulation Of MiRNA Metabolic Process Transcription Regulator Complex DNA-binding Transcription Factor Binding Nuclear Speck DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Negative Regulation Of Metabolic Process Regulation Of MiRNA Transcription DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Metabolic Process Regulation Of MiRNA Metabolic Process Nucleobase-containing Compound Metabolic Process	Nucleus Transcription Regulator Complex MiRNA Processing Response To Anesthetic Identical Protein Binding Nuclear Receptor Binding Heteromeric SMAD Protein Complex SMAD Protein Complex DEAD/H-box RNA Helicase Binding Response To Cobalt Ion Chromatin Macromolecule Metabolic Process Regulation Of Primary Metabolic Process Co-SMAD Binding Primary MiRNA Processing Regulation Of Metabolic Process I-SMAD Binding Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Execution Phase Of Apoptosis Ubiquitin Protein Ligase Binding Regulation Of Macromolecule Metabolic Process Transcription Coregulator Activity SMAD Protein Signal Transduction Nucleoplasm Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Double-strand Break Repair Nuclear Body Positive Regulation Of Cartilage Development Enzyme Binding Cytoplasm Cellular Response To Radiation DNA Methylation-dependent Constitutive Heterochromatin Formation Negative Regulation Of Cardiac Muscle Hypertrophy Protein-containing Complex Ureteric Bud Development Negative Regulation Of Muscle Hypertrophy Meiosis I Transcription Regulator Inhibitor Activity RNA Polymerase II-specific DNA-binding Transcription Factor Binding Response To External Biotic Stimulus Cytosol Caspase Complex Response To Steroid Hormone Post-translational Protein Modification Chromatin Binding Negative Regulation Of DNA-templated Transcription Transcription Coactivator Binding Negative Regulation Of RNA Biosynthetic Process Mesonephric Epithelium Development Mesonephric Tubule Development
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