AIMP2 and PCMT1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		AIMP2	PCMT1
Gene Name		aminoacyl tRNA synthetase complex-interacting multifunctional protein 2	protein-L-isoaspartate (D-aspartate) O-methyltransferase
Image
Gene Ontology Annotations	Cellular Component	Nucleus Cytosol Membrane	Cytoplasm Endoplasmic Reticulum Vesicle Extracellular Vesicular Exosome
	Molecular Function	Protein Binding	Protein-L-isoaspartate (D-aspartate) O-methyltransferase Activity
	Biological Process	TRNA Aminoacylation For Protein Translation Apoptotic Process Negative Regulation Of Cell Proliferation Gene Expression Positive Regulation Of Protein Ubiquitination Type II Pneumocyte Differentiation	Protein Methylation Protein Repair
Pathways		Cytosolic tRNA aminoacylation tRNA Aminoacylation
Drugs			S-Adenosyl-L-Homocysteine
Diseases
GWAS
Protein-Protein Interactions		48 interactors: ACTB AIMP1 APP BCAS2 BLOC1S4 BYSL C19orf57 CEP170P1 CHD3 DARS DARS2 DEAF1 DSN1 EPRS EPS8 FGB FHL3 FUBP1 GYS1 ICE1 KARS KDR KIAA1377 KLC2 LMO2 LMO3 LNX1 LUC7L2 MATR3 MCF2L MIS18A NDEL1 NECAB2 NGFRAP1 PARK2 PCMT1 PLEKHF2 PPP2R1A PRKAA2 PSME1 TANK TERF2IP TFIP11 TP53 TRAF2 TRMT2A ZC3H12A ZGPAT	7 interactors: AIMP2 APOA1 APOE CHD3 CREBBP RPIA VKORC1
Entrez ID		7965	5110
HPRD ID		02915	08908
Ensembl ID		ENSG00000106305	ENSG00000120265
Uniprot IDs		A8MU58 Q13155	B7Z972 H7BY58 J3KP72 P22061
PDB IDs		4DPG	1I1N 1KR5
Enriched GO Terms of Interacting Partners?		RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process Cellular Component Assembly TRNA Aminoacylation For Protein Translation Axon Cargo Transport TRNA Aminoacylation Cell Cycle Process NcRNA Metabolic Process Mitotic Cell Cycle Process Positive Regulation Of Cellular Metabolic Process Regulation Of Autophagy Mitotic Cell Cycle Apoptotic Process Platelet Aggregation Negative Regulation Of Reactive Oxygen Species Metabolic Process Programmed Cell Death Positive Regulation Of Signal Transduction Regulation Of Signal Transduction Regulation Of Mitochondrion Degradation Protein Complex Assembly Microtubule-based Transport Immune System Process Cell Death Death TRNA Metabolic Process Cellular Response To Organic Substance Cytoskeleton-dependent Intracellular Transport Blood Coagulation Cell Cycle Cellular Macromolecule Biosynthetic Process Hemostasis Positive Regulation Of Peptidase Activity Macromolecule Biosynthetic Process Cellular Process Cellular Amino Acid Metabolic Process Enzyme Linked Receptor Protein Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Proteolysis Positive Regulation Of Metabolic Process Regulation Of Intracellular Signal Transduction Regulation Of Apoptotic Process Cellular Metabolic Process Response To Wounding Regulation Of Signaling Regulation Of Cellular Ketone Metabolic Process	High-density Lipoprotein Particle Clearance Positive Regulation Of Cholesterol Esterification High-density Lipoprotein Particle Assembly Regulation Of Cholesterol Esterification Peripheral Nervous System Axon Regeneration Phospholipid Efflux Small Molecule Metabolic Process High-density Lipoprotein Particle Remodeling Protein-lipid Complex Assembly Reverse Cholesterol Transport Plasma Lipoprotein Particle Remodeling Positive Regulation Of Steroid Metabolic Process Cholesterol Efflux Regulation Of Cdc42 Protein Signal Transduction Plasma Lipoprotein Particle Clearance Regulation Of Cholesterol Transport Axon Regeneration Anion Homeostasis Neuron Projection Regeneration Regulation Of Plasma Lipoprotein Particle Levels Positive Regulation Of Lipid Biosynthetic Process Cholesterol Transport Sterol Transport Response To Axon Injury Phototransduction, Visible Light Cholesterol Homeostasis Sterol Homeostasis Retinoid Metabolic Process Diterpenoid Metabolic Process Detection Of Visible Light Positive Regulation Of Low-density Lipoprotein Particle Receptor Catabolic Process Positive Regulation Of Dendritic Spine Maintenance Negative Regulation Of Dendritic Spine Maintenance Negative Regulation Of Phospholipid Efflux Negative Regulation Of Lipid Transport Across Blood Brain Barrier Positive Regulation Of Lipid Transport Across Blood Brain Barrier Negative Regulation Of Cell Adhesion Molecule Production Positive Regulation Of Postsynaptic Membrane Organization Negative Regulation Of Postsynaptic Membrane Organization Phospholipid Transport Regulation Of Lipid Transport Phototransduction Regulation Of Steroid Metabolic Process Negative Regulation Of Inflammatory Response Detection Of Light Stimulus Cholesterol Metabolic Process Lipid Homeostasis Lipoprotein Biosynthetic Process Isoprenoid Metabolic Process Positive Regulation Of Neurofibrillary Tangle Assembly
Tagcloud ?		4x20 abl abrogated bbb c57 compacts dopaminergic e3 easily endothelium inno irreversible microvessel mitigated mptp nanomolar neurodegeneration neuroprotective nigra nitrative parkin pars pd pharmacokinetic striatum substantia th translated ubiquitously	adaptive adult altered approximate aspartate brains catalyses compensatory extracts glucose gsk3beta hippocampus insulin isoaspartate isoaspartyl juvenile lacking methyltransferase mice mild pdk peak possibly progressive propose testes tolerance transduction upstream
Tagcloud (Difference) ?		4x20 abl abrogated bbb c57 compacts dopaminergic e3 easily endothelium inno irreversible microvessel mitigated mptp nanomolar neurodegeneration neuroprotective nigra nitrative parkin pars pd pharmacokinetic striatum substantia th translated ubiquitously	adaptive adult altered approximate aspartate brains catalyses compensatory extracts glucose gsk3beta hippocampus insulin isoaspartate isoaspartyl juvenile lacking methyltransferase mice mild pdk peak possibly progressive propose testes tolerance transduction upstream
Tagcloud (Intersection) ?