NKAP and DDX41

Number of citations of the paper that reports this interaction (PMID 22365833)
24

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		NKAP	DDX41
Gene Name		NFKB activating protein	DEAD (Asp-Glu-Ala-Asp) box polypeptide 41
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm	Endoplasmic Reticulum Cytosol Membrane Catalytic Step 2 Spliceosome
	Molecular Function	Chromatin Binding Protein Binding Chromatin DNA Binding Poly(A) RNA Binding	DNA Binding Helicase Activity Protein Binding ATP Binding Zinc Ion Binding Poly(A) RNA Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Notch Signaling Pathway Stem Cell Maintenance Granulocyte Differentiation T Cell Differentiation In Thymus Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Alpha-beta T Cell Differentiation Hematopoietic Stem Cell Proliferation	MRNA Splicing, Via Spliceosome RNA Processing Apoptotic Process Multicellular Organismal Development Regulation Of Type I Interferon Production Positive Regulation Of Type I Interferon Production Cellular Response To Interferon-beta Innate Immune Response Positive Regulation Of Transcription From RNA Polymerase II Promoter Defense Response To Virus
Pathways			Regulation of innate immune responses to cytosolic DNA Cytosolic sensors of pathogen-associated DNA STING mediated induction of host immune responses IRF3-mediated induction of type I IFN Innate Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		18 interactors: BUB3 CEP70 DDX41 DHX15 DHX8 FAM124A FRA10AC1 LUC7L2 PCBP2 PPIG PRPF3 PRPF40A RBM39 RBMX2 SRPK1 THAP1 TTC14 U2AF1	4 interactors: CEP70 CHAF1A NKAP SIAH1
Entrez ID		79576	51428
HPRD ID		06666	10490
Ensembl ID		ENSG00000101882	ENSG00000183258
Uniprot IDs		Q8N5F7	Q9UJV9
PDB IDs			2P6N
Enriched GO Terms of Interacting Partners?		RNA Splicing RNA Processing MRNA Processing MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Cellular Metabolic Process Regulation Of Type I Interferon Production Defense Response To Virus Ribonucleoprotein Complex Assembly Metabolic Process
Tagcloud ?			adding adjuvant bx795 cd80 cd86 cyclic cytosol di dinucleotide dinucleotides fusogenicity gmp helicase immunology interferons irf3 liposomal liposome liposomes messengers microbiology pass pope raw264 stimulator sting tank tbk1 ysk05
Tagcloud (Difference) ?			adding adjuvant bx795 cd80 cd86 cyclic cytosol di dinucleotide dinucleotides fusogenicity gmp helicase immunology interferons irf3 liposomal liposome liposomes messengers microbiology pass pope raw264 stimulator sting tank tbk1 ysk05
Tagcloud (Intersection) ?