DDX41 and CHAF1A

Number of citations of the paper that reports this interaction (PMID 21209461)
3

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, pull down)

		DDX41	CHAF1A
Gene Name		DEAD (Asp-Glu-Ala-Asp) box polypeptide 41	chromatin assembly factor 1, subunit A (p150)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Cytosol Membrane Catalytic Step 2 Spliceosome	Nuclear Chromatin CAF-1 Complex Protein Complex
	Molecular Function	DNA Binding Helicase Activity Protein Binding ATP Binding Zinc Ion Binding Poly(A) RNA Binding	Chromatin Binding Protein Binding Identical Protein Binding Unfolded Protein Binding Chromo Shadow Domain Binding
	Biological Process	MRNA Splicing, Via Spliceosome RNA Processing Apoptotic Process Multicellular Organismal Development Regulation Of Type I Interferon Production Positive Regulation Of Type I Interferon Production Cellular Response To Interferon-beta Innate Immune Response Positive Regulation Of Transcription From RNA Polymerase II Promoter Defense Response To Virus	DNA Replication DNA Repair DNA Replication-dependent Nucleosome Assembly Transcription, DNA-templated Regulation Of Transcription, DNA-templated Protein Complex Assembly Cell Cycle Chromatin Assembly
Pathways		Regulation of innate immune responses to cytosolic DNA Cytosolic sensors of pathogen-associated DNA STING mediated induction of host immune responses IRF3-mediated induction of type I IFN Innate Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: CEP70 CHAF1A NKAP SIAH1	37 interactors: ANP32A ANP32B ASF1A ASF1B BLM CBX1 CBX5 CDC7 CDK2 CHAF1B DBF4 DDX41 HIST1H3E HIST3H3 HMGB2 LZTR1 MBD1 MSH6 PABPC1 PCBD2 PCNA RBFOX2 REL SET SUMO1 SUMO2 SUMO3 TCERG1 TCF4 TRIM28 XRCC5 XRCC6 YWHAB YWHAE YWHAG YWHAQ ZNF408
Entrez ID		51428	10036
HPRD ID		10490	03148
Ensembl ID		ENSG00000183258	ENSG00000167670
Uniprot IDs		Q9UJV9	Q13111
PDB IDs		2P6N
Enriched GO Terms of Interacting Partners?			Regulation Of Metabolic Process Regulation Of Nitrogen Compound Metabolic Process DNA Metabolic Process Regulation Of RNA Metabolic Process Negative Regulation Of Cellular Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Gene Expression Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Biosynthetic Process Negative Regulation Of RNA Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process DNA Conformation Change Cellular Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process DNA Repair Protein-DNA Complex Assembly Chromosome Organization Nitrogen Compound Metabolic Process Nucleosome Assembly DNA Replication-dependent Nucleosome Assembly Chromatin Assembly Nucleosome Organization Cellular Response To DNA Damage Stimulus Chromatin Assembly Or Disassembly Regulation Of Cellular Process Positive Regulation Of Cellular Metabolic Process DNA Packaging Positive Regulation Of Metabolic Process Cellular Response To Stress Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Protein Sumoylation DNA Recombination Positive Regulation Of Intracellular Transport Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Response To Stress Telomere Maintenance Organelle Organization DNA Replication Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Cellular Macromolecule Biosynthetic Process Protein Complex Assembly Macromolecule Biosynthetic Process Gene Expression Positive Regulation Of Macromolecule Biosynthetic Process Cellular Metabolic Process
Tagcloud ?		adding adjuvant bx795 cd80 cd86 cyclic cytosol di dinucleotide dinucleotides fusogenicity gmp helicase immunology interferons irf3 liposomal liposome liposomes messengers microbiology pass pope raw264 stimulator sting tank tbk1 ysk05	3a aggressive cohorts concept driven gsea intact malignancies malignancy mcm3 mcm6 mdm2 multifactorial networks neuroblastoma nutlin oncogene opposing overcome p53 potently reciprocally repressed repression rrm2 signature signatures subset worst
Tagcloud (Difference) ?		adding adjuvant bx795 cd80 cd86 cyclic cytosol di dinucleotide dinucleotides fusogenicity gmp helicase immunology interferons irf3 liposomal liposome liposomes messengers microbiology pass pope raw264 stimulator sting tank tbk1 ysk05	3a aggressive cohorts concept driven gsea intact malignancies malignancy mcm3 mcm6 mdm2 multifactorial networks neuroblastoma nutlin oncogene opposing overcome p53 potently reciprocally repressed repression rrm2 signature signatures subset worst
Tagcloud (Intersection) ?