DDX41

Description		DEAD-box helicase 41
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm Endoplasmic Reticulum Cytosol Membrane Catalytic Step 2 Spliceosome
	Molecular Function	Nucleotide Binding Nucleic Acid Binding DNA Binding RNA Binding RNA Helicase Activity MRNA Binding Helicase Activity Protein Binding ATP Binding Zinc Ion Binding Hydrolase Activity ATP Hydrolysis Activity Metal Ion Binding
	Biological Process	MRNA Splicing, Via Spliceosome MRNA Processing Apoptotic Process Cell Population Proliferation RNA Splicing Cell Differentiation Positive Regulation Of Type I Interferon Production Cellular Response To Interferon-beta Positive Regulation Of Transcription By RNA Polymerase II Defense Response To Virus CGAS/STING Signaling Pathway
Pathways		STING mediated induction of host immune responses Regulation of innate immune responses to cytosolic DNA IRF3-mediated induction of type I IFN mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		11 interacting genes: AIDA CEBPA CEP70 CHAF1A KLC2 NKAPL OGT SIAH1 TRIM26 TRIM41 TUBG1
Entrez ID		51428
HPRD ID		10490
Ensembl ID		ENSG00000183258
Uniprot IDs		B3KRK2 Q9UJV9
PDB IDs		2P6N 5GVR 5GVS 5H1Y 8C6J
Enriched GO Terms of Interacting Partners?
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