NKAP and BUB3

Number of citations of the paper that reports this interaction (PMID 22365833)
24

Data Source:
BioGRID (two hybrid)

		NKAP	BUB3
Gene Name		NFKB activating protein	BUB3 mitotic checkpoint protein
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm	Kinetochore Condensed Chromosome Kinetochore Nucleoplasm Cytosol
	Molecular Function	Chromatin Binding Protein Binding Chromatin DNA Binding Poly(A) RNA Binding	Protein Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Notch Signaling Pathway Stem Cell Maintenance Granulocyte Differentiation T Cell Differentiation In Thymus Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Alpha-beta T Cell Differentiation Hematopoietic Stem Cell Proliferation	Mitotic Sister Chromatid Segregation Mitotic Cell Cycle Mitotic Spindle Assembly Checkpoint Attachment Of Spindle Microtubules To Kinetochore Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Cell Division Meiotic Cell Cycle Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Spindle Assembly Checkpoint
Pathways			Mitotic Prometaphase Separation of Sister Chromatids Inactivation of APC/C via direct inhibition of the APC/C complex APC/C:Cdc20 mediated degradation of mitotic proteins Mitotic Anaphase Regulation of APC/C activators between G1/S and early anaphase Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components M Phase APC/C-mediated degradation of cell cycle proteins Cell Cycle, Mitotic Inactivation of APC/C via direct inhibition of the APC/C complex Mitotic Spindle Checkpoint Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components Resolution of Sister Chromatid Cohesion Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins Regulation of mitotic cell cycle APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint Cell Cycle Checkpoints Mitotic Metaphase and Anaphase
Drugs
Diseases
GWAS
Protein-Protein Interactions		18 interactors: BUB3 CEP70 DDX41 DHX15 DHX8 FAM124A FRA10AC1 LUC7L2 PCBP2 PPIG PRPF3 PRPF40A RBM39 RBMX2 SRPK1 THAP1 TTC14 U2AF1	17 interactors: BUB1 BUB1B CPNE1 EXOC3 HDAC1 HDAC2 NKAP PARP1 PARP2 PSTPIP1 RPL37A SUGT1 THRA TOP1 UBA1 WBP4 ZNF207
Entrez ID		79576	9184
HPRD ID		06666	04761
Ensembl ID		ENSG00000101882	ENSG00000154473
Uniprot IDs		Q8N5F7	O43684
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Splicing RNA Processing MRNA Processing MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Cellular Metabolic Process Regulation Of Type I Interferon Production Defense Response To Virus Ribonucleoprotein Complex Assembly Metabolic Process	Mitotic Spindle Assembly Checkpoint Spindle Assembly Checkpoint Mitotic Spindle Checkpoint Negative Regulation Of Chromosome Segregation Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Nuclear Division Spindle Checkpoint Regulation Of Mitotic Metaphase/anaphase Transition Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Fungiform Papilla Formation Negative Regulation Of Cell Cycle Negative Regulation Of Proteasomal Protein Catabolic Process Fungiform Papilla Morphogenesis Negative Regulation Of Cellular Protein Catabolic Process Circadian Regulation Of Gene Expression Positive Regulation Of Receptor Biosynthetic Process Negative Regulation Of Cell Division Regulation Of Chromosome Segregation Fungiform Papilla Development Eyelid Development In Camera-type Eye Negative Regulation Of Chromosome Organization Negative Regulation Of Cellular Metabolic Process Hair Follicle Placode Formation Tongue Morphogenesis Mitotic Nuclear Division Regulation Of Receptor Biosynthetic Process Negative Regulation Of Protein Catabolic Process Histone H4 Deacetylation Regulation Of Mitotic Nuclear Division Organelle Organization Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Mitotic Cell Cycle Negative Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Transcription From RNA Polymerase II Promoter Protein ADP-ribosylation Mitotic Cell Cycle Checkpoint Cell Division Histone H3 Deacetylation Circadian Rhythm Transcription Initiation From RNA Polymerase II Promoter Tongue Development Chromatin Remodeling Histone H3-K9 Modification Regulation Of Proteasomal Protein Catabolic Process Intracellular Receptor Signaling Pathway Regulation Of Cell Cycle Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Regulation Of Chromosome Organization Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Mitotic Cell Cycle
Tagcloud ?			abrogates anaphase apc assembles attached bubr1 cdc20 centrally checkpoint comet correctly cyclosome delays disassemble disassembled disassembly hela hydrolysis inactivated mad2 mcc mitotic p31 participates spindle subcomplex sufficiently trip13 turned
Tagcloud (Difference) ?			abrogates anaphase apc assembles attached bubr1 cdc20 centrally checkpoint comet correctly cyclosome delays disassemble disassembled disassembly hela hydrolysis inactivated mad2 mcc mitotic p31 participates spindle subcomplex sufficiently trip13 turned
Tagcloud (Intersection) ?