FCRL2 and PLP1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		FCRL2	PLP1
Description		Fc receptor like 2	proteolipid protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane External Side Of Plasma Membrane Cell Surface Membrane	Plasma Membrane Membrane Myelin Sheath Synapse
	Molecular Function	Transmembrane Signaling Receptor Activity Protein Binding Protein Phosphatase Binding Signaling Adaptor Activity	Structural Molecule Activity Protein Binding Structural Constituent Of Myelin Sheath Identical Protein Binding
	Biological Process	Immune Response Cell Surface Receptor Signaling Pathway Cell-cell Signaling	Inflammatory Response Chemical Synaptic Transmission Axon Ensheathment Positive Regulation Of Gene Expression Astrocyte Development Substantia Nigra Development Central Nervous System Myelination Myelination Long-chain Fatty Acid Biosynthetic Process Axon Development
Pathways
Drugs
Diseases			Hypomyelinating leukodystrophy (HLD); Pelizaeus-Merzbacher disease (PMD) Hereditary spastic paraplegia (SPG)
GWAS		Neurological blood protein biomarker levels ( 31320639) smoking initiation in schizophrenia ( 33691233)
Interacting Genes		5 interacting genes: JAGN1 MAL NCK2 PLP1 ZDHHC22	91 interacting genes: ADGRG3 AKT1 AQP10 AQP6 ARL13B BCL2L13 BIK CALN1 CALR CANX CD40 CD74 CDIPT CLDN2 CLDN20 CLEC2D CLN8 CREB3 CREB3L1 CYB5R3 CYBC1 DCT DYRK1A DYSF EDA2R ELOVL4 ERGIC3 FAM209A FCRL2 FFAR2 FKBP7 FNDC9 GAST GJA8 GPR42 GPR61 HAS3 HTR2C IER3IP1 IFITM3 ITGAV JAGN1 JPH1 KLRC1 LEPROTL1 LEUTX LHFPL5 LMNA MAG MBP MFF MGST3 MS4A3 MS4A4A MTIF3 MUC1 MYADM NRG1 PI16 PIGP PTPRN RELL2 RMDN3 RNF24 SLC10A6 SLC16A2 SLC18A1 SLC1A5 SLC26A6 SLC35E2A SLC35E3 SLC35H1 SLC41A3 SMIM3 SPNS3 STX1A STX4 SUSD3 TMEM106C TMEM14B TMEM182 TMEM242 TMEM243 TMEM254 TMEM31 TMEM45B TMEM52B TMEM97 TMPRSS2 UPK2 VAT1
Entrez ID		79368	5354
HPRD ID		07351	02321
Ensembl ID		ENSG00000132704	ENSG00000123560
Uniprot IDs		B4DVJ9 B4E0W2 Q96LA5	A0A0S2Z4D4 A8K9L3 B4DI30 P60201
PDB IDs			2XPG
Enriched GO Terms of Interacting Partners?		Structural Constituent Of Myelin Sheath Central Nervous System Myelination Protein Insertion Into Plasma Membrane Myelination Axon Ensheathment Endoplasmic Reticulum Hinge Region Between Urothelial Plaques Of Apical Plasma Membrane Positive Regulation Of Apoptotic Signaling Pathway Membrane Raft Polarization Protein Localization To Paranode Region Of Axon Establishment Of Protein Localization To Membrane Peptidase Activator Activity Involved In Apoptotic Process Regulation Of Translation Initiation In Response To Endoplasmic Reticulum Stress Positive Regulation Of Translation In Response To Endoplasmic Reticulum Stress Granulocyte Colony-stimulating Factor Signaling Pathway Membrane Raft Distribution Membrane Raft Localization Signal Complex Assembly Response To Endoplasmic Reticulum Stress Positive Regulation Of Translation In Response To Stress Neutrophil Differentiation Negative Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Protein Localization To Axon Schmidt-Lanterman Incisure Regulation Of Translation In Response To Endoplasmic Reticulum Stress Positive Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Translational Initiation In Response To Stress Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Negative Regulation Of PERK-mediated Unfolded Protein Response Establishment Of Protein Localization Immunological Synapse Formation Apical Protein Localization Dendritic Spine Development Regulation Of PERK-mediated Unfolded Protein Response Regulation Of Apoptotic Signaling Pathway Astrocyte Development Insulin Metabolic Process Protein Palmitoylation	Membrane Protein Binding Plasma Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Transmembrane Transport Negative Regulation Of Apoptotic Signaling Pathway Compact Myelin Antiporter Activity
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?