RETREG3 and VAMP1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		RETREG3	VAMP1
Description		reticulophagy regulator family member 3	vesicle associated membrane protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Protein-containing Complex Endoplasmic Reticulum Tubular Network	Mitochondrion Mitochondrial Outer Membrane Cytosol Plasma Membrane Membrane Transport Vesicle Cytoplasmic Vesicle Membrane Synaptic Vesicle Membrane SNARE Complex Cytoplasmic Vesicle Azurophil Granule Membrane Specific Granule Membrane Neuron Projection Synapse Tertiary Granule Membrane
	Molecular Function	Protein Binding Endoplasmic Reticulum-autophagosome Adaptor Activity	SNAP Receptor Activity Protein Binding Syntaxin Binding
	Biological Process	Autophagy Endoplasmic Reticulum Organization Positive Regulation Of Neuron Projection Development Collagen Catabolic Process Reticulophagy Substrate Localization To Autophagosome Endoplasmic Reticulum Tubular Network Organization	Vesicle Fusion Vesicle-mediated Transport SNARE Complex Assembly
Pathways			Toxicity of botulinum toxin type D (botD) Toxicity of botulinum toxin type F (botF) Toxicity of botulinum toxin type G (botG)
Drugs			Botulinum toxin type B
Diseases
GWAS		Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892)	Hip geometry ( 17903296)
Interacting Genes		107 interacting genes: ABHD16A ACSL5 AGPAT4 AGTRAP ANKRD46 ARL6IP1 ARLN ARPC3 ATP6V0C BET1 BNIP1 C16orf92 C1GALT1 CCDC167 CCL4L2 CDIPT CDS1 CLCA4 CMTM3 CMTM5 CMTM7 CSGALNACT2 CYB5B CYP4F2 DERL1 DHRSX ERG28 FAXDC2 FKBP8 FUNDC2 GABARAPL1 GABARAPL2 GIMAP5 GOSR2 HMOX2 HTATIP2 JAGN1 LEMD1 LPAR3 LPCAT2 LRCH4 MAL2 MALL MAP1LC3A MCRS1 MFF MOB2 MOSPD3 NRM ORMDL2 ORMDL3 OTULINL PKMYT1 PLP2 PLPP6 PNLIPRP1 PRAF2 RABAC1 RUSF1 SCD SEC22A SENP2 SERP2 SFT2D1 SFXN3 SLC30A3 SLC39A6 SMCO4 SMIM1 STAP1 STX5 STX7 STX8 SYNGR1 TBRG4 TCEA2 TECR TMEM100 TMEM11 TMEM120B TMEM128 TMEM176A TMEM18 TMEM203 TMEM218 TMEM222 TMEM237 TMEM239 TMEM243 TMEM254 TMEM31 TMEM42 TMEM60 TMEM65 TMPPE TPRG1 TSNARE1 TSPO2 UBIAD1 VAMP1 VAMP3 VAMP4 VAMP5 VAPA VAPB YIPF1 YIPF6	37 interacting genes: AQP6 ARL13B BCAP31 CDKN2A CRB3 CREB3L1 CYB5R3 DNAJC5 EBP ELOVL4 ELOVL7 ERGIC3 FAM210B FCER1G GPR152 KASH5 LAPTM5 LMNA REEP4 RETREG3 RNF24 SCN3B SEC11C SGMS2 SLC10A6 SLC30A8 SNAP23 SNAP29 STX1A STX1B STX4 TMEM101 TMEM14B TMEM35A TMX2 VAPA VAPB
Entrez ID		162427	6843
HPRD ID		14108	01716
Ensembl ID		ENSG00000141699	ENSG00000139190
Uniprot IDs		K7EQI9 Q86VR2	F5GZV7 P23763
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum SNAP Receptor Activity SNARE Complex Membrane Fusion Endomembrane System Organelle Fusion Organelle Membrane Fusion Membrane Organization Golgi Vesicle Transport Vesicle Fusion Protein Binding Organelle Localization By Membrane Tethering Vesicle Organization Lipid Biosynthetic Process Membrane Docking SNARE Binding Golgi Membrane Vesicle-mediated Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Cellular Response To Nitrogen Starvation Endoplasmic Reticulum Organization Vesicle Docking CDP-diacylglycerol Metabolic Process Transport Vesicle SNARE Complex Assembly Mitochondrial Outer Membrane Phosphatidylethanolamine Binding FFAT Motif Binding Endoplasmic Reticulum Membrane Organization Organelle Membrane Bounding Membrane Of Organelle Synaptic Vesicle Phospholipid Metabolic Process Azurophil Granule Membrane COPII-coated Vesicle Budding Endoplasmic Reticulum-plasma Membrane Tethering Intracellular Sphingolipid Homeostasis Negative Regulation Of Ceramide Biosynthetic Process Phospholipid Biosynthetic Process Lipid Metabolic Process Establishment Of Protein Localization Late Endosome Menaquinone Metabolic Process Negative Regulation Of Sphingolipid Biosynthetic Process Chloride Channel Inhibitor Activity Endoplasmic Reticulum Localization Serine Palmitoyltransferase Complex Positive Regulation Of B Cell Receptor Signaling Pathway	Membrane Endoplasmic Reticulum Membrane SNAP Receptor Activity Organelle Localization By Membrane Tethering Membrane Docking SNARE Complex Membrane Organization Secretion By Cell Exocytosis Organelle Localization Membrane Fusion Secretion Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Signal Release Intracellular Protein Localization Endoplasmic Reticulum Vesicle Fusion To Plasma Membrane Vesicle Fusion Organelle Membrane Fusion Vesicle-mediated Transport Vesicle Organization Synaptic Vesicle Membrane Organization Positive Regulation Of Protein Localization To Cell Surface Organelle Fusion Endoplasmic Reticulum Organization Cellular Localization Establishment Of Localization In Cell FFAT Motif Binding Golgi Vesicle Transport Positive Regulation Of Protein Localization COPII-coated Vesicle Budding Endoplasmic Reticulum-plasma Membrane Tethering Synaptic Vesicle Exocytosis Sphingolipid Biosynthetic Process Cytoplasmic Vesicle Regulated Exocytosis Regulation Of Protein Localization To Cell Surface Fatty Acid Elongation, Monounsaturated Fatty Acid Fatty Acid Elongase Activity Fatty Acid Elongation, Polyunsaturated Fatty Acid ATP-dependent Protein Binding Endoplasmic Reticulum Localization Regulation Of Protein Localization Fatty Acid Elongation, Saturated Fatty Acid Protein Binding Presynapse Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Positive Regulation Of Regulated Secretory Pathway Azurophil Granule Membrane Host-mediated Activation Of Viral Genome Replication
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