SARNP and YTHDF1

Number of citations of the paper that reports this interaction (PubMedID 34133714)
84

Data Source:
BioGRID (two hybrid)

		SARNP	YTHDF1
Description		SAP domain containing ribonucleoprotein	YTH N6-methyladenosine RNA binding protein F1
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GO Annotations	Cellular Component	Transcription Export Complex Nucleus Nucleoplasm Nuclear Speck Cytoplasmic Ribonucleoprotein Granule	P-body Cytoplasm Cytoplasmic Stress Granule
	Molecular Function	DNA Binding Chromatin Binding RNA Binding Protein Binding	RNA Binding MRNA Binding Protein Binding Ribosome Binding N6-methyladenosine-containing RNA Reader Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II MRNA Export From Nucleus Regulation Of Translation Poly(A)+ MRNA Export From Nucleus MRNA Transport	Immune System Process Regulation Of Antigen Processing And Presentation Learning Memory Stress Granule Assembly Regulation Of MRNA Stability Positive Regulation Of Translation Positive Regulation Of Translational Initiation MRNA Destabilization Organelle Assembly Regulation Of Long-term Synaptic Potentiation Regulation Of Axon Guidance
Pathways		Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS		Kawasaki disease ( 33772158) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878)	Response to cytadine analogues (cytosine arabinoside) ( 24483146)
Interacting Genes		9 interacting genes: CEBPA CSNK2B DAPK1 DDX39A DDX39B ESR1 EXOSC8 VHL YTHDF1	42 interacting genes: ABHD11 BATF2 BICD2 C6orf15 CFTR CLK2 CPSF7 CTTN DMRTB1 DYNC1I1 ERI3 FAM168A FHIT HEY1 HSF4 ITSN2 KRTAP13-1 KRTAP26-1 KRTAP7-1 KRTAP8-1 LASP1 MAGED1 MOV10 MSX2 OIP5 PPIL3 PRR32 PRRC2B QKI RBFOX2 RBM22 RBMS3 RBPMS SARNP SF1 SNCA SNRPA TLE5 TMED9 VPS37C XRN2 ZNF34
Entrez ID		84324	54915
HPRD ID		16716	11691
Ensembl ID		ENSG00000205323	ENSG00000149658
Uniprot IDs		P82979	Q9BYJ9
PDB IDs		2DO1	4RCI 4RCJ 7PCU 7QKN 7QL7 7YYE 7YYF 7YYJ 7YZ8 8BS4
Enriched GO Terms of Interacting Partners?		Identical Protein Binding Negative Regulation Of Metabolic Process Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Macromolecule Biosynthetic Process Notch Signaling Pathway Chromatin Binding Nucleoplasm CHOP-C/EBP Complex RNA Metabolic Process Nucleus Regulation Of Macromolecule Metabolic Process Macromolecule Metabolic Process Negative Regulation Of Biosynthetic Process RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Chromatin Response To Vitamin B2 White Fat Cell Proliferation Positive Regulation Of RNA Metabolic Process Memory C/EBP Complex Protein Kinase CK2 Complex Symbiont-mediated Disruption Of Host Cell PML Body Regulation Of NMDA Receptor Activity DAPK1-calmodulin Complex Positive Regulation Of Autophagic Cell Death Nuclear Estrogen Receptor Activity TFIIB-class Transcription Factor Binding Prostate Epithelial Cord Elongation Positive Regulation Of Nitric-oxide Synthase Activity Mammary Gland Branching Involved In Pregnancy Antral Ovarian Follicle Growth Helicase Activity RNA Export From Nucleus MRNA Export From Nucleus MRNA Transport Nuclear Export MRNA Binding RNA Helicase Activity Negative Regulation Of RNA Export From Nucleus U5 SnRNA 3'-end Processing U1 SnRNA 3'-end Processing Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Hematopoietic Stem Cell Proliferation Rb-E2F Complex Release From Viral Latency Regulation Of Branching Involved In Prostate Gland Morphogenesis Epithelial Cell Proliferation Involved In Mammary Gland Duct Elongation Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Catabolic Process	Nucleic Acid Binding MRNA Processing RNA Binding Regulation Of RNA Splicing MRNA Splicing, Via Spliceosome MRNA Metabolic Process Negative Regulation Of Biosynthetic Process RNA Processing RNA Splicing, Via Transesterification Reactions RNA Splicing MRNA Binding
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