CRELD2 and MEST

Number of citations of the paper that reports this interaction (PubMedID 21900206)
0

Data Source:
BioGRID (two hybrid)

		CRELD2	MEST
Description		CRELD disulfide isomerase 2	mesoderm specific transcript
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Endoplasmic Reticulum Golgi Apparatus	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Extracellular Exosome
	Molecular Function	Protein Disulfide Isomerase Activity Calcium Ion Binding Protein Binding Isomerase Activity	Catalytic Activity Protein Binding Hydrolase Activity
	Biological Process		Mesoderm Development Regulation Of Lipid Storage Response To Retinoic Acid
Pathways
Drugs
Diseases
GWAS		Acne (severe) ( 24927181)	Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		8 interacting genes: C8orf33 CDKN2A CHRNA4 CHRNB2 HOXA1 LTB4R2 MEST SUV39H1	23 interacting genes: APP BAG6 BLOC1S2 C6orf47 CD300C CEP70 CIAO2A CIDEB CMTM3 CRELD2 DBN1 FBXO7 FEZ1 FST GAD2 HGS ING5 KIFAP3 LIME1 MPZL2 RNF19B ZNF205 ZNF579
Entrez ID		79174	4232
HPRD ID		08455	06776
Ensembl ID		ENSG00000184164	ENSG00000106484
Uniprot IDs		Q6UXH1	A4D1L9 B4DQW6 Q5EB52
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Depolarization Acetylcholine Binding Behavioral Response To Nicotine Neurotransmitter Receptor Complex Acetylcholine Receptor Activity Acetylcholine-gated Monoatomic Cation-selective Channel Activity Acetylcholine-gated Channel Complex Cation Channel Complex Synaptic Transmission, Cholinergic Regulation Of Dopamine Secretion Ligand-gated Monoatomic Ion Channel Activity Neuromuscular Synaptic Transmission Extracellular Ligand-gated Monoatomic Ion Channel Activity Regulation Of Catecholamine Secretion Sensory Perception Of Pain Response To Nicotine Acetylcholine Receptor Signaling Pathway Postsynaptic Signal Transduction Response To Hypoxia Response To Decreased Oxygen Levels Cognition Excitatory Postsynaptic Potential Visual Behavior Regulation Of B Cell Proliferation Synaptic Membrane Response To Oxygen Levels Ligase Inhibitor Activity Lateral Geniculate Nucleus Development Semicircular Canal Formation Regulation Of Behavior Regulation Of Amine Transport Regulation Of Membrane Potential Regulation Of Postsynaptic Membrane Potential Abducens Nerve Formation Optokinetic Behavior Leukotriene B4 Receptor Activity Sensory Perception Positive Regulation Of Macrophage Apoptotic Process Apoptotic Process Involved In Mammary Gland Involution ENoSc Complex Leukotriene Receptor Activity Positive Regulation Of Apoptotic Process Involved In Mammary Gland Involution Regulation Of B Cell Activation Senescence-associated Heterochromatin Focus Synaptic Transmission Involved In Micturition Vestibulocochlear Nerve Development Regulation Of Circadian Sleep/wake Cycle, REM Sleep Histone H3K9 Trimethyltransferase Activity Leukotriene Signaling Pathway Negative Regulation Of Protein Neddylation	Gamma-tubulin Binding
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