CARD14 and TRIP13

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CARD14	TRIP13
Gene Name		caspase recruitment domain family, member 14	thyroid hormone receptor interactor 13
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Plasma Membrane	Male Germ Cell Nucleus Nucleus
	Molecular Function	CARD Domain Binding	Transcription Cofactor Activity Protein Binding ATP Binding Identical Protein Binding
	Biological Process	Positive Regulation Of Protein Phosphorylation Apoptotic Process Activation Of NF-kappaB-inducing Kinase Activity Tumor Necrosis Factor-mediated Signaling Pathway Negative Regulation Of Apoptotic Process Positive Regulation Of NF-kappaB Transcription Factor Activity	Oocyte Maturation Double-strand Break Repair Transcription From RNA Polymerase II Promoter Synaptonemal Complex Assembly Reciprocal Meiotic Recombination Male Meiosis I Female Meiosis I Spermatogenesis Spermatid Development Oogenesis Regulation Of Nucleic Acid-templated Transcription
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		3 interactors: BCL10 TRIP13 ZNF471	75 interactors: ADAM15 AMDHD2 ARL11 ARSA ASB13 C11orf54 C4orf33 CARD14 CCBL1 CD99 COMT CPSF3L CRMP1 CRYBA2 CYB5R2 DDAH2 DIP2A DPYSL4 DTX2 FNDC3B GALT GLYCTK GPRIN2 GPSM1 HDHD3 KRTAP12-1 KRTAP12-2 KRTAP26-1 KRTAP3-2 LASP1 LNX1 LOXL4 LRR1 LRRC61 M1AP MAD2L1BP MAD2L2 METTL15 MGAT5B MORN3 MPPED2 MVP NIF3L1 NME4 PARK2 PARP11 PBLD PCMTD2 PELI1 PLAC8 PLK3 PLSCR3 PLSCR4 PPP2CA QARS RBPMS RHOXF2 SCP2 SEC24A SELENBP1 SEMA4G SIGLEC5 SMUG1 SPRYD7 STAMBP STAMBPL1 TEX37 THRB TINAGL1 TLDC1 TNRC6A TPT1 WDYHV1 ZNF34 ZNF655
Entrez ID		79092	9319
HPRD ID		06235	05145
Ensembl ID		ENSG00000141527	ENSG00000071539
Uniprot IDs		Q9BXL6	Q15645
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Mast Cell Cytokine Production Lymphotoxin A Biosynthetic Process Interleukin-6 Biosynthetic Process Negative Regulation Of Mature B Cell Apoptotic Process Interleukin-6 Production Positive Regulation Of Interleukin-8 Biosynthetic Process B Cell Apoptotic Process Negative Regulation Of B Cell Apoptotic Process Regulation Of Interleukin-8 Biosynthetic Process Female Meiosis I T Cell Apoptotic Process Regulation Of B Cell Apoptotic Process Synaptonemal Complex Assembly Response To Food Cytokine Biosynthetic Process Oocyte Maturation Synaptonemal Complex Organization Positive Regulation Of Myeloid Leukocyte Cytokine Production Involved In Immune Response Male Meiosis I Cytokine Metabolic Process Positive Regulation Of Interleukin-8 Production Female Meiotic Division Response To Fungus Reciprocal Meiotic Recombination Regulation Of T Cell Receptor Signaling Pathway Oocyte Development Oocyte Differentiation Positive Regulation Of Cytokine Production Involved In Immune Response Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Defense Response Regulation Of RNA Metabolic Process Negative Regulation Of Leukocyte Apoptotic Process Synapsis Homologous Chromosome Segregation Male Meiosis Regulation Of Lymphocyte Apoptotic Process Positive Regulation Of Cytokine Biosynthetic Process Cellular Response To Mechanical Stimulus Regulation Of Nitrogen Compound Metabolic Process Regulation Of Cytokine Production Involved In Immune Response Oogenesis Meiotic Chromosome Segregation Positive Regulation Of Extrinsic Apoptotic Signaling Pathway	Negative Regulation Of Epithelial To Mesenchymal Transition Negative Regulation Of Stem Cell Differentiation Catabolic Process Pyrimidine Nucleobase Catabolic Process Negative Regulation Of Mitotic Cell Cycle Phospholipid Scrambling Regulation Of Epithelial To Mesenchymal Transition Metabolic Process Endomembrane System Organization Regulation Of SMAD Protein Import Into Nucleus Negative Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Protein Phosphorylation Phospholipid Transport Carboxylic Acid Catabolic Process Negative Regulation Of Protein Metabolic Process Small Molecule Metabolic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Cell Morphogenesis Involved In Differentiation Negative Regulation Of Programmed Cell Death Dopamine Metabolic Process Regulation Of Protein Autophosphorylation Positive Regulation Of Homocysteine Metabolic Process RRNA Base Methylation Negative Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Glutaminyl-tRNA Aminoacylation Lipid Hydroperoxide Transport Positive Regulation Of Intracellular Cholesterol Transport UDP-glucose Catabolic Process Positive Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of Mitochondrial Fusion Cellular Response To Phosphate Starvation Male Meiosis Chromosome Separation Regulation Of Protein Metabolic Process Negative Regulation Of Cell Death Negative Regulation Of Phosphorylation Protein Ubiquitination Regulation Of Apoptotic Process
Tagcloud ?			abrogates anaphase apc assembles attached bub3 bubr1 cdc20 centrally checkpoint comet correctly cyclosome delays disassemble disassembled disassembly hela hydrolysis inactivated mad2 mcc mitotic p31 participates spindle subcomplex sufficiently turned
Tagcloud (Difference) ?			abrogates anaphase apc assembles attached bub3 bubr1 cdc20 centrally checkpoint comet correctly cyclosome delays disassemble disassembled disassembly hela hydrolysis inactivated mad2 mcc mitotic p31 participates spindle subcomplex sufficiently turned
Tagcloud (Intersection) ?