CARD14

Name	caspase recruitment domain family member 14
Structure	No pdb structure
Novel Interactors	1 novel interactors: TP53
Interactors	7 interactors: BCL10 MAP3K1 PRPF31 TRIP13 UBAC1 ZNF471 ZNF648
GO Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Aggresome
	Molecular Function	Protein Binding CARD Domain Binding
	Biological Process	Positive Regulation Of Protein Phosphorylation Apoptotic Process Activation Of NF-kappaB-inducing Kinase Activity Positive Regulation Of Macromolecule Metabolic Process Tumor Necrosis Factor-mediated Signaling Pathway Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Positive Regulation Of Canonical NF-kappaB Signal Transduction Regulation Of Immune Response Positive Regulation Of NF-kappaB Transcription Factor Activity
GWAS	Fasting glucose ( 34074324 ) Hirschsprung disease ( 26887379 ) Moyamoya disease ( 29273593 ) Psoriasis ( 23143594 )
Entrez ID	79092
HPRD ID	06235
Ensembl ID	ENSG00000141527
Uniprot IDs	A0A494C0J4 A0A994J6G4 Q9BXL6
PDB IDs	Not available
GO Terms Enriched among Interactors ?	General Transcription Initiation Factor Binding T Cell Apoptotic Process Cellular Response To Mechanical Stimulus Oligodendrocyte Apoptotic Process Negative Regulation Of Fermentation Intrinsic Apoptotic Signaling Pathway In Response To Hypoxia Lymphocyte Apoptotic Process Regulation Of Lymphocyte Apoptotic Process Negative Regulation Of Pentose-phosphate Shunt Negative Regulation Of Helicase Activity Oxidative Stress-induced Premature Senescence Negative Regulation Of Glucose Catabolic Process To Lactate Via Pyruvate Negative Regulation Of Chromosome Organization Negative Regulation Of G1 To G0 Transition Glucose Catabolic Process To Lactate Via Pyruvate Germ Cell Nucleus Cellular Response To Actinomycin D Leukocyte Apoptotic Process Protease Binding Polkadots Positive Regulation Of Lymphotoxin A Production Meiotic Recombination Checkpoint Signaling SnRNP Binding U4atac SnRNP Ribonucleoprotein Complex Localization U4atac SnRNA Binding Histone Deacetylase Regulator Activity Positive Regulation Of Thymocyte Apoptotic Process Positive Regulation Of RNA Polymerase II Transcription Preinitiation Complex Assembly Response To Actinomycin D T Cell Proliferation Involved In Immune Response Regulation Of G1 To G0 Transition Positive Regulation Of Apoptotic Signaling Pathway Glial Cell Apoptotic Process Cellular Response To UV-C ATP-dependent DNA/DNA Annealing Activity CBM Complex Positive Regulation Of Mast Cell Cytokine Production Negative Regulation Of Mature B Cell Apoptotic Process SnoRNA Localization Negative Regulation Of Mitotic Cell Cycle Phase Transition B Cell Lineage Commitment Regulation Of Pentose-phosphate Shunt Spliceosomal Tri-snRNP Complex Mitochondrial DNA Repair Bone Marrow Development Stress-induced Premature Senescence Female Meiosis I U4 SnRNA Binding Response To Mechanical Stimulus