NOC4L and PRSS23

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		NOC4L	PRSS23
Gene Name		nucleolar complex associated 4 homolog (S. cerevisiae)	protease, serine, 23
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleolus Integral Component Of Membrane Noc4p-Nop14p Complex Nuclear Membrane Small-subunit Processome	Nucleus Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Poly(A) RNA Binding	Serine-type Endopeptidase Activity
	Biological Process	Maturation Of SSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) RRNA Processing	Proteolysis
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		13 interactors: BHLHE40 DAZAP2 DNAJA3 IKZF1 KRT15 NECAB2 NT5C2 PLSCR1 PRSS23 SSSCA1 TSC22D4 USHBP1 VIM	25 interactors: ACTG1 APP B2M CHP1 EFNA3 FXR1 GRK6 HSPA4 MAPK8IP2 NCAPD3 NIPBL NOC4L ODF2L PDDC1 PDPK1 PHF23 PPIA RACGAP1 RECQL4 RPL4P5 SHMT1 SLC25A6 TCF12 TMEM222 TRAPPC4
Entrez ID		79050	11098
HPRD ID		14543	07149
Ensembl ID		ENSG00000184967	ENSG00000150687
Uniprot IDs		Q9BVI4	B4E2J3 O95084
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Neutrophil Differentiation Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Regulation Of Cell Activation Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of DNA Topoisomerase (ATP-hydrolyzing) Activity Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process T Cell Differentiation Cell Activation Negative Regulation Of Interferon-gamma-mediated Signaling Pathway Phosphatidylserine Biosynthetic Process Positive Regulation Of NK T Cell Differentiation Activation-induced Cell Death Of T Cells Bergmann Glial Cell Differentiation Positive Regulation Of T Cell Activation Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Homotypic Cell-cell Adhesion Positive Regulation Of Granulocyte Differentiation Regulation Of Fc Receptor Mediated Stimulatory Signaling Pathway Skeletal Muscle Acetylcholine-gated Channel Clustering Lymphocyte Differentiation Positive Regulation Of Cell-cell Adhesion Regulation Of Innate Immune Response Phospholipid Scrambling Regulation Of Transcription From RNA Polymerase II Promoter Nucleobase-containing Compound Metabolic Process Positive Regulation Of Immune System Process Mitochondrial DNA Replication T Cell Aggregation T Cell Activation Lymphocyte Aggregation Leukocyte Aggregation Heterocycle Metabolic Process Regulation Of T Cell Activation Adenosine Metabolic Process Apoptotic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Cell Activation Lymph Node Development Regulation Of Gene Expression Programmed Cell Death T Cell Apoptotic Process Peyer's Patch Development Leukocyte Cell-cell Adhesion Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Intermediate Filament Organization Homotypic Cell-cell Adhesion Negative Regulation Of Cellular Metabolic Process	Platelet Activation Blood Coagulation Hemostasis Cell Differentiation Cellular Component Assembly Regulation Of Body Fluid Levels Organelle Organization Wound Healing Multicellular Organismal Development Generation Of Neurons Cell Activation Dendrite Development System Development Response To Stress Response To Wounding Neurogenesis Mating Behavior Nervous System Development Regulation Of Protein Localization Response To Stimulus Neuron Projection Development Cell Development Developmental Process Cytokinesis, Initiation Of Separation Actomyosin Contractile Ring Assembly Uncoating Of Virus Mating Anatomical Structure Development Neuron Development Retina Homeostasis Movement Of Cell Or Subcellular Component Cell Morphogenesis Involved In Neuron Differentiation Protein Targeting To Mitochondrion Protein Complex Assembly Regulation Of Cellular Localization Immune System Process Platelet Degranulation Negative Regulation Of Rho-dependent Protein Serine/threonine Kinase Activity Synaptic Growth At Neuromuscular Junction Active Induction Of Host Immune Response By Virus Mitotic Sister Chromatid Segregation Protein Localization To Mitochondrion Protein Folding Cognition Neuron Projection Morphogenesis Positive Regulation Of Cellular Protein Metabolic Process Neuron Differentiation Mitotic Nuclear Division Sister Chromatid Segregation Regulation Of Establishment Of Protein Localization
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