NOC4L and KRTAP19-6

Number of citations: 50 (PubMedID 32296183)
Data Source: BioGRID (two hybrid)

		NOC4L	KRTAP19-6
Name		nucleolar complex associated 4 homolog	keratin associated protein 19-6
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Membrane Noc4p-Nop14p Complex Nuclear Membrane Small-subunit Processome	Cytosol Intermediate Filament
	Molecular Function	RNA Binding Protein Binding	Protein Binding
	Biological Process	RRNA Processing Ribosome Biogenesis	None
Pathways		rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol	Keratinization
GWAS		Body mass index ( 26426971 ) Hirschsprung disease ( 26887379 ) Response to antidepressants (symptom improvement) ( 29160301 ) Response to SSRI (symptom remission) ( 29160301 )	No GWAS studies recorded
Interacting Genes		24 interacting genes: BHLHE40 CEBPA DAZAP2 DNAJA3 DUSP29 EPM2AIP1 IKZF1 KRT15 KRTAP19-6 LINC00839 LNPK NECAB2 NT5C2 OGT OXER1 PICK1 PLSCR1 PRSS23 TSC22D4 UBQLN2 USHBP1 VIM ZBTB42 ZNRD2	69 interacting genes: ATOSB ATPAF2 BCAS2 C11orf16 CATSPER1 CCDC24 CCNK CERK CIMIP1 CREB5 CRY2 CSKMT CYSRT1 DMRTB1 DTX2 ENKD1 FANCL FNDC11 FOXH1 GPANK1 GUCD1 HOXA1 HSF4 INCA1 KIFC3 KPRP KRTAP12-4 KRTAP26-1 KRTAP6-3 KRTAP9-3 LASP1 LONRF1 MEIS2 MGAT5B MKRN3 MYOZ3 MYPOP NOC4L NTAQ1 OIP5 OTX1 PATZ1 PLAC8 PLEKHN1 PLSCR3 PLSCR4 POU4F2 PROP1 PSMB2 RBPMS2 RHOXF2 RUNX1T1 SAXO4 SLC25A18 SMN1 SMN2 SNRPB SNRPC SPAG8 SPMIP6 TEKT4 TEKT5 TENT5B TFAP2D TSPYL6 VENTX VGLL3 VPS37C ZNF414
Entrez ID		79050	337973
HPRD ID		14543	11210
Ensembl ID		ENSG00000184967	ENSG00000186925
Uniprot IDs		Q9BVI4	A4FU57 Q3LI70
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		Negative Regulation Of G Protein-coupled Receptor Internalization Protein Domain Specific Binding Identical Protein Binding Carbohydrate Homeostasis Glucose Homeostasis Negative Regulation Of Endocytosis Regulation Of Receptor Internalization Negative Regulation Of Receptor Internalization Negative Regulation Of Cellular Component Organization	Axonemal A Tubule Inner Sheath Protein Binding Sperm Flagellum Sperm Motility Flagellated Sperm Motility Cilium-dependent Cell Motility Cilium Movement Involved In Cell Motility Chromatin Spliceosomal SnRNP Assembly SMN-Sm Protein Complex Nucleus Cilium Movement Cajal Body Motile Cilium DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Cilium SMN Complex Spliceosomal Complex Assembly