RNF183 and FATE1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid, two hybrid)
HPRD (two hybrid)

		RNF183	FATE1
Description		ring finger protein 183	fetal and adult testis expressed 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Lysosome Lysosomal Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Membrane Cis-Golgi Network Membrane	Cytoplasm Mitochondrion Mitochondrial Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Mitochondria-associated Endoplasmic Reticulum Membrane Contact Site
	Molecular Function	Protein Binding Zinc Ion Binding Transferase Activity Metal Ion Binding Ubiquitin Protein Ligase Activity	Protein Binding Ubiquitin Protein Ligase Binding Identical Protein Binding
	Biological Process	Protein Polyubiquitination Apoptotic Process Protein Ubiquitination Response To Endoplasmic Reticulum Stress Protein Autoubiquitination Positive Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway	Apoptotic Process Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Mitochondrial Calcium Ion Concentration
Pathways
Drugs
Diseases
GWAS		Appendicular lean mass ( 33097823)	Systemising ( 31508503)
Interacting Genes		12 interacting genes: APP BCL2 BCL2L1 EWSR1 FATE1 FBP1 GOPC IFFO1 KXD1 TAX1BP3 UBE2K UBE2W	99 interacting genes: AGTRAP APOL3 AQP9 ASGR2 ATCAY BCL2L2 BIK BNIP2 BNIP3 BNIP3L BSND BTN2A2 C1QL4 CALN1 CCDC70 CD302 CD79A CD83 CDC37 CERS4 CREB3L3 CSF2RA CTRL CXCR1 CXCR3 DCTN5 DNAJC30 EMD FAM177A1 FAM209A FRMD8 GIMAP5 GINM1 GOSR2 GPR25 HSD17B13 INPP5K KASH5 KCNS2 LMNA LNPEP LRRC25 MARCHF2 MARCHF3 MARCHF5 MARVELD2 MFF MOSPD3 MR1 NDUFB11 NRG4 NRSN1 OCLN OTOP2 PIN4 PKMYT1 PLP2 PRRG2 RBFA RIC3 RNF183 RPRM RTP2 SCAMP5 SEC22A SEC22C SEC23A SEC23B SLC38A1 SLC41A2 SLC7A1 SLC7A14 SMIM14 SNAP47 SSMEM1 SYNDIG1 SYNE4 SYNGR1 SYNGR2 SYNPR TBP TIMMDC1 TM4SF4 TMEM11 TMEM179B TMEM201 TMEM74 TRAF2 TRAF3IP3 UBE2I UNC93B1 USHBP1 USP20 VSIG4 VSTM1 YIPF2 YIPF4 ZCCHC12 ZFPL1
Entrez ID		138065	89885
HPRD ID		10082	02346
Ensembl ID		ENSG00000165188	ENSG00000147378
Uniprot IDs		Q96D59	Q969F0
PDB IDs
Enriched GO Terms of Interacting Partners?		Dendritic Cell Apoptotic Process Negative Regulation Of Protein Localization Negative Regulation Of Dendritic Cell Apoptotic Process BH3 Domain Binding Bcl-2 Family Protein Complex Negative Regulation Of Protein Localization To Cell Surface Ubiquitin Protein Ligase Binding Identical Protein Binding Negative Regulation Of Anoikis Programmed Cell Death Involved In Cell Development Release Of Cytochrome C From Mitochondria Regulation Of Extrinsic Apoptotic Signaling Pathway Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Intrinsic Apoptotic Signaling Pathway Neuron Maturation Negative Regulation Of Signaling Negative Regulation Of Signal Transduction Regulation Of Protein Localization Negative Regulation Of Cell Communication Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Regulation Of Anoikis Ubiquitin Conjugating Enzyme Activity Channel Activity Mitochondrial Outer Membrane Regulation Of Protein Localization To Cell Surface Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Growth Regulation Of Neuron Apoptotic Process Regulation Of Response To Calcium Ion Regulation Of Glycolytic Process Amylin Binding Positive Regulation Of Toll Signaling Pathway Response To Peptide Cellular Response To CAMP Response To Cytokine Epithelial Cell Apoptotic Process Negative Regulation Of Retinal Cell Programmed Cell Death Negative Regulation Of Cellular PH Reduction Ovarian Follicle Development Response To Gamma Radiation Leukocyte Apoptotic Process Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Negative Regulation Of Leukocyte Apoptotic Process Apoptotic Process In Bone Marrow Cell Negative Regulation Of Anion Channel Activity Regulation Of Mitochondrial Membrane Permeability Protein Polyubiquitination	Membrane Protein Binding Endoplasmic Reticulum Nuclear Envelope Membrane Organization Endoplasmic Reticulum Membrane Cytoplasmic Vesicle Spindle Pole Centrosome Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Synaptic Vesicle Membrane Organization Vesicle-mediated Transport Perinuclear Region Of Cytoplasm Positive Regulation Of Mitochondrial Fission COPII-coated Vesicle Budding
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