RNF183

Description		ring finger protein 183
Image		No pdb structure
GO Annotations	Cellular Component	Lysosome Lysosomal Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Membrane Cis-Golgi Network Membrane
	Molecular Function	Protein Binding Zinc Ion Binding Transferase Activity Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Protein Polyubiquitination Apoptotic Process Protein Ubiquitination Response To Endoplasmic Reticulum Stress Protein Autoubiquitination Positive Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Appendicular lean mass ( 33097823)
Interacting Genes		12 interacting genes: APP BCL2 BCL2L1 EWSR1 FATE1 FBP1 GOPC IFFO1 KXD1 TAX1BP3 UBE2K UBE2W
Entrez ID		138065
HPRD ID		10082
Ensembl ID		ENSG00000165188
Uniprot IDs		Q96D59
PDB IDs
Enriched GO Terms of Interacting Partners?		Dendritic Cell Apoptotic Process Negative Regulation Of Protein Localization Negative Regulation Of Dendritic Cell Apoptotic Process BH3 Domain Binding Bcl-2 Family Protein Complex Negative Regulation Of Protein Localization To Cell Surface Ubiquitin Protein Ligase Binding Identical Protein Binding Negative Regulation Of Anoikis Programmed Cell Death Involved In Cell Development Release Of Cytochrome C From Mitochondria Regulation Of Extrinsic Apoptotic Signaling Pathway Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Intrinsic Apoptotic Signaling Pathway Neuron Maturation Negative Regulation Of Signaling Negative Regulation Of Signal Transduction Regulation Of Protein Localization Negative Regulation Of Cell Communication Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Regulation Of Anoikis Ubiquitin Conjugating Enzyme Activity Channel Activity Mitochondrial Outer Membrane Regulation Of Protein Localization To Cell Surface Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Growth Regulation Of Neuron Apoptotic Process Regulation Of Response To Calcium Ion Regulation Of Glycolytic Process Amylin Binding Positive Regulation Of Toll Signaling Pathway Response To Peptide Cellular Response To CAMP Response To Cytokine Epithelial Cell Apoptotic Process Negative Regulation Of Retinal Cell Programmed Cell Death Negative Regulation Of Cellular PH Reduction Ovarian Follicle Development Response To Gamma Radiation Leukocyte Apoptotic Process Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Negative Regulation Of Leukocyte Apoptotic Process Apoptotic Process In Bone Marrow Cell Negative Regulation Of Anion Channel Activity Regulation Of Mitochondrial Membrane Permeability Protein Polyubiquitination
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