RNF183 and TAX1BP3

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		RNF183	TAX1BP3
Description		ring finger protein 183	Tax1 binding protein 3
Image		No pdb structure
GO Annotations	Cellular Component	Lysosome Lysosomal Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Membrane Cis-Golgi Network Membrane	Fibrillar Center Nucleus Cytoplasm Cytosol Plasma Membrane Actin Cytoskeleton Membrane Extracellular Exosome
	Molecular Function	Protein Binding Zinc Ion Binding Transferase Activity Metal Ion Binding Ubiquitin Protein Ligase Activity	Protein Binding Beta-catenin Binding
	Biological Process	Protein Polyubiquitination Apoptotic Process Protein Ubiquitination Response To Endoplasmic Reticulum Stress Protein Autoubiquitination Positive Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway	Rho Protein Signal Transduction Negative Regulation Of Cell Population Proliferation Wnt Signaling Pathway Negative Regulation Of Wnt Signaling Pathway Regulation Of Cdc42 Protein Signal Transduction Negative Regulation Of Protein Localization To Cell Surface
Pathways			RHO GTPases Activate Rhotekin and Rhophilins
Drugs
Diseases
GWAS		Appendicular lean mass ( 33097823)
Interacting Genes		12 interacting genes: APP BCL2 BCL2L1 EWSR1 FATE1 FBP1 GOPC IFFO1 KXD1 TAX1BP3 UBE2K UBE2W	14 interacting genes: ARHGEF16 ARNT2 CDK5RAP3 CTNNB1 DTX1 GATA1 GLS GLS2 PLK4 RNF183 RTKN STAU1 TCEA2 TRIM29
Entrez ID		138065	30851
HPRD ID		10082	18160
Ensembl ID		ENSG00000165188	ENSG00000213977
Uniprot IDs		Q96D59	A0A087X282 O14907
PDB IDs			2KG2 2L4S 2L4T 2VZ5 3GJ9 3SFJ 4E3B 4NNL 4NNM
Enriched GO Terms of Interacting Partners?		Dendritic Cell Apoptotic Process Negative Regulation Of Protein Localization Negative Regulation Of Dendritic Cell Apoptotic Process BH3 Domain Binding Bcl-2 Family Protein Complex Negative Regulation Of Protein Localization To Cell Surface Ubiquitin Protein Ligase Binding Identical Protein Binding Negative Regulation Of Anoikis Programmed Cell Death Involved In Cell Development Release Of Cytochrome C From Mitochondria Regulation Of Extrinsic Apoptotic Signaling Pathway Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Intrinsic Apoptotic Signaling Pathway Neuron Maturation Negative Regulation Of Signaling Negative Regulation Of Signal Transduction Regulation Of Protein Localization Negative Regulation Of Cell Communication Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Regulation Of Anoikis Ubiquitin Conjugating Enzyme Activity Channel Activity Mitochondrial Outer Membrane Regulation Of Protein Localization To Cell Surface Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Growth Regulation Of Neuron Apoptotic Process Regulation Of Response To Calcium Ion Regulation Of Glycolytic Process Amylin Binding Positive Regulation Of Toll Signaling Pathway Response To Peptide Cellular Response To CAMP Response To Cytokine Epithelial Cell Apoptotic Process Negative Regulation Of Retinal Cell Programmed Cell Death Negative Regulation Of Cellular PH Reduction Ovarian Follicle Development Response To Gamma Radiation Leukocyte Apoptotic Process Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Negative Regulation Of Leukocyte Apoptotic Process Apoptotic Process In Bone Marrow Cell Negative Regulation Of Anion Channel Activity Regulation Of Mitochondrial Membrane Permeability Protein Polyubiquitination	L-glutamine Catabolic Process Glutaminase Activity Glutamate Biosynthetic Process Glutamine Metabolic Process Transcription Regulator Complex DNA-templated Transcription Mesenchymal Stem Cell Differentiation Positive Regulation Of Determination Of Dorsal Identity Negative Regulation Of Mitotic Cell Cycle, Embryonic Centrosome Beta-catenin-ICAT Complex Negative Regulation Of Mesenchymal To Epithelial Transition Involved In Metanephros Morphogenesis Glial Cell Fate Determination Protein-DNA Complex Renal Inner Medulla Development In Utero Embryonic Development Scrib-APC-beta-catenin Complex Regulation Of Apoptotic Process Embryo Development Ending In Birth Or Egg Hatching Multicellular Organism Development Renal Outer Medulla Development Transcription Coregulator Binding Renal Vesicle Formation Canonical Wnt Signaling Pathway Involved In Mesenchymal Stem Cell Differentiation Myeloid Cell Differentiation Chordate Embryonic Development Positive Regulation Of Branching Involved In Lung Morphogenesis Neural Plate Development Regulation Of Glycoprotein Biosynthetic Process Regulation Of Programmed Cell Death Transcription By RNA Polymerase II Basophil Differentiation P53 Binding Eosinophil Fate Commitment Regulation Of Primitive Erythrocyte Differentiation Erythrocyte Differentiation Glutamate Metabolic Process Amino Acid Biosynthetic Process Glutamine Family Amino Acid Metabolic Process Septin Ring Organization Oviduct Development Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Mononuclear Cell Differentiation Protein Modification By Small Protein Conjugation Fungiform Papilla Formation Beta-catenin-TCF7L2 Complex Astrocyte-dopaminergic Neuron Signaling Positive Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Regulation Of Centriole-centriole Cohesion Embryonic Skeletal Limb Joint Morphogenesis
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?