NOTUM

Description		notum, palmitoleoyl-protein carboxylesterase
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GO Annotations	Cellular Component	Extracellular Region Endoplasmic Reticulum Lumen
	Molecular Function	Phospholipase C Activity Protein Binding Lipase Activity Hydrolase Activity Carboxylic Ester Hydrolase Activity Protein-containing Complex Destabilizing Activity Palmitoleyl Hydrolase Activity
	Biological Process	Wnt Signaling Pathway Negative Regulation Of Wnt Signaling Pathway Regulation Of Bone Mineralization Bone Development Negative Regulation Of Canonical Wnt Signaling Pathway Protein Depalmitoleylation
Pathways		Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Release of Hh-Np from the secreting cell Post-translational protein phosphorylation
Drugs
Diseases
GWAS		Blond vs. brown/black hair color ( 30531825) Blood protein levels ( 30072576) Diverticular disease ( 30177863)
Interacting Genes		1 interacting genes: ZNF655
Entrez ID		147111
HPRD ID		14073
Ensembl ID		ENSG00000185269
Uniprot IDs		Q6P988
PDB IDs		4UYU 4UYW 4UYZ 4UZ1 4UZ5 4UZ6 4UZ7 4UZ9 4UZA 4UZL 4UZQ 4WBH 6R8P 6R8Q 6R8R 6T2H 6T2K 6TR5 6TR6 6TR7 6TUZ 6TV4 6YSK 6YUW 6YUY 6YV0 6YV2 6YV4 6YXI 6ZUV 6ZVL 6ZYF 7ARG 7B2V 7B2Y 7B2Z 7B37 7B3F 7B3G 7B3H 7B3I 7B3P 7B3X 7B45 7B4X 7B50 7B7W 7B7X 7B7Y 7B84 7B86 7B87 7B89 7B8A 7B8C 7B8D 7B8F 7B8G 7B8J 7B8K 7B8L 7B8M 7B8N 7B8O 7B8U 7B8X 7B8Y 7B8Z 7B98 7B99 7B9D 7B9I 7B9N 7B9U 7BA1 7BAC 7BAP 7BC8 7BC9 7BCC 7BCD 7BCF 7BCH 7BCI 7BCK 7BCL 7BD2 7BD3 7BD4 7BD5 7BD6 7BD8 7BD9 7BDA 7BDB 7BDC 7BDD 7BDF 7BDG 7BDH 7BLI 7BLS 7BLT 7BLU 7BLW 7BM1 7BM3 7BM7 7BMB 7BMD 7BN5 7BN8 7BNB 7BNC 7BND 7BNE 7BNF 7BNJ 7BNL 7BO1 7BO2 7BO5 7PJR 7PK3 7PKV 7QVZ 8BSP 8BSQ 8BSR 8BSZ 8BT0 8BT2 8BT5 8BT7 8BT8 8BTA 8BTC 8BTE 8BTH 8BTI
Enriched GO Terms of Interacting Partners?
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