CLEC12B and VMA21

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CLEC12B	VMA21
Description		C-type lectin domain family 12 member B	vacuolar ATPase assembly factor VMA21
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane External Side Of Plasma Membrane Membrane Protein-containing Complex	Lysosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane ER To Golgi Transport Vesicle Membrane Membrane Cytoplasmic Vesicle Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane
	Molecular Function	Protein Binding Protein Phosphatase Binding Carbohydrate Binding Signaling Receptor Regulator Activity Signaling Receptor Inhibitor Activity	Protein Binding
	Biological Process	Natural Killer Cell Inhibitory Signaling Pathway Negative Regulation Of Natural Killer Cell Mediated Cytotoxicity Melanocyte Proliferation Negative Regulation Of Receptor Signaling Pathway Via STAT Negative Regulation Of Signaling Receptor Activity	Lysosomal Lumen Acidification Vacuolar Proton-transporting V-type ATPase Complex Assembly
Pathways
Drugs
Diseases
GWAS		Malaria ( 31844061) Sensory disturbances after bilateral sagittal split ramus osteotomy ( 23834954) Systolic blood pressure in sickle cell anemia ( 24058526)
Interacting Genes		11 interacting genes: IL1RL1 JAGN1 LPAR3 LSMEM2 MALL OPRM1 PLLP PMP22 SCD SEC22A VMA21	29 interacting genes: ABHD16A ADAM33 AQP6 ARL6IP1 ATP13A1 ATP6V0B BNIP1 CDIPT CLEC12B DAGLA HMOX2 INSIG2 LHFPL5 LYPD6B NINJ2 NIPAL3 ORMDL1 PLLP RTP2 SCD SLC25A46 SLC35E4 TECR THSD7A TMEM107 TMEM60 VAMP2 YIF1A YIPF1
Entrez ID		387837	203547
HPRD ID		18266	18578
Ensembl ID		ENSG00000256660	ENSG00000160131
Uniprot IDs		A0A140VK10 Q2HXU8	Q3ZAQ7
PDB IDs
Enriched GO Terms of Interacting Partners?		Compact Myelin Myelination Axon Ensheathment Bleb Assembly Structural Constituent Of Myelin Sheath Membrane Myelin Assembly G-protein Alpha-subunit Binding G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Morphine Receptor Activity Negative Regulation Of Wnt Protein Secretion Beta-endorphin Receptor Activity Monounsaturated Fatty Acid Biosynthetic Process Interleukin-33 Binding Negative Regulation Of Protein Secretion Palmitoyl-CoA 9-desaturase Activity Interleukin-33 Receptor Activity Regulation Of Transcytosis Endoplasmic Reticulum Cellular Response To Morphine Stearoyl-CoA 9-desaturase Activity Regulation Of NMDA Receptor Activity Lysophosphatidic Acid Receptor Activity Negative Regulation Of Protein Transport Endoplasmic Reticulum Membrane Granulocyte Colony-stimulating Factor Signaling Pathway Vacuolar Proton-transporting V-type ATPase Complex Assembly Negative Regulation Of Establishment Of Protein Localization Oxidoreductase Activity, Acting On Paired Donors, With Oxidation Of A Pair Of Donors Resulting In The Reduction Of Molecular Oxygen To Two Molecules Of Water Interleukin-1 Receptor Activity Myeloid Leukocyte Differentiation Negative Regulation Of Secretion By Cell	Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum Membrane Organization Endoplasmic Reticulum Monoacylglycerol Lipase Activity Lipid Biosynthetic Process Acylglycerol Metabolic Process Neutral Lipid Metabolic Process Establishment Of Protein Localization To Membrane Craniofacial Suture Morphogenesis Myelination Axon Ensheathment Acylglycerol Catabolic Process Nitrate Transmembrane Transporter Activity SNAP Receptor Activity Lipid Metabolic Process Glycerolipid Metabolic Process Monounsaturated Fatty Acid Biosynthetic Process CDP-diacylglycerol-inositol 3-phosphatidyltransferase Activity Extraction Of Mislocalized Protein From ER Membrane ABC-type Manganese Transporter Activity Membrane Protein Dislocase Activity
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?