ZNF205 and WT1

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		ZNF205	WT1
Gene Name		zinc finger protein 205	Wilms tumor 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleus Nucleoplasm Nucleolus Cytoplasm Nuclear Speck
	Molecular Function	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Zinc Ion Binding	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Sequence-specific DNA Binding Transcription Factor Activity RNA Binding Protein Binding Zinc Ion Binding Sequence-specific DNA Binding Transcription Regulatory Region DNA Binding C2H2 Zinc Finger Domain Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Regulation Of Transcription, DNA-templated Positive Regulation Of Hydrogen Peroxide Biosynthetic Process Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway	Negative Regulation Of Transcription From RNA Polymerase II Promoter Vasculogenesis Ureteric Bud Development Branching Involved In Ureteric Bud Morphogenesis Kidney Development Regulation Of Organ Formation Transcription, DNA-templated Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Germ Cell Development Thorax And Anterior Abdomen Determination Heart Development Sex Determination Negative Regulation Of Cell Proliferation RNA Splicing Gonad Development Male Gonad Development Tissue Development Negative Regulation Of Translation Negative Regulation Of Cell Growth Adrenal Gland Development Male Genitalia Development Epithelial Cell Differentiation Glomerulus Development Glomerular Basement Membrane Development Adrenal Cortex Formation Camera-type Eye Development Positive Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Mesenchymal To Epithelial Transition Positive Regulation Of Heart Growth Diaphragm Development Cardiac Muscle Cell Fate Commitment Visceral Serous Pericardium Development Cellular Response To CAMP Cellular Response To Gonadotropin Stimulus Metanephric Mesenchyme Development Glomerular Visceral Epithelial Cell Differentiation Posterior Mesonephric Tubule Development Metanephric Epithelium Development Metanephric S-shaped Body Morphogenesis Negative Regulation Of Metanephric Glomerular Mesangial Cell Proliferation Positive Regulation Of Male Gonad Development Negative Regulation Of Female Gonad Development Positive Regulation Of Metanephric Ureteric Bud Development
Pathways		Generic Transcription Pathway
Drugs
Diseases
GWAS			Tuberculosis ( 22306650)
Protein-Protein Interactions		12 interactors: C8orf33 CALCOCO2 CCDC85B CDC37 HDAC6 ILK MAPK6 MDFI MEST TRAF2 UBQLN4 WT1	23 interactors: AREG CIAO1 CREBBP DVL3 EGR1 FHL2 KRT40 KRTAP10-3 KRTAP10-8 MDM2 NPM3 PAWR PAX2 PRKACA TAOK1 TP53 TP63 TP73 U2AF2 UBE2I WTAP WTIP ZNF205
Entrez ID		7755	7490
HPRD ID		04580	06163
Ensembl ID		ENSG00000122386	ENSG00000184937
Uniprot IDs		I0J0A3 O95201	P19544 Q6PI38
PDB IDs			1LU6 1XF7 2G7T 2G7V 2G7W 2G7X 2JP9 2JPA 2PRT 3HPJ 3MYJ
Enriched GO Terms of Interacting Partners?		Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Metabolic Process Positive Regulation Of MAP Kinase Activity Positive Regulation Of Protein Serine/threonine Kinase Activity Regulation Of Protein Kinase Activity Regulation Of MAP Kinase Activity Regulation Of Kinase Activity Branching Involved In Ureteric Bud Morphogenesis Positive Regulation Of JUN Kinase Activity Regulation Of Cell Growth Ureteric Bud Morphogenesis Positive Regulation Of Hydrogen Peroxide-mediated Programmed Cell Death Negative Regulation Of Metanephric Glomerular Mesangial Cell Proliferation Hsp90 Deacetylation Regulation Of JUN Kinase Activity Nephron Morphogenesis Renal Tubule Morphogenesis Positive Regulation Of Chaperone-mediated Protein Complex Assembly Visceral Serous Pericardium Development Posterior Mesonephric Tubule Development Adrenal Cortex Formation Positive Regulation Of Metanephric Ureteric Bud Development Thorax And Anterior Abdomen Determination Polyubiquitinated Misfolded Protein Transport Positive Regulation Of MAPK Cascade Renal Tubule Development Cellular Response To Reactive Oxygen Species Regulation Of Protein Phosphorylation Kidney Morphogenesis Positive Regulation Of Protein Kinase Activity Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Kinase Activity Negative Regulation Of Nucleic Acid-templated Transcription Axis Specification Negative Regulation Of RNA Biosynthetic Process Ureteric Bud Development Mesonephric Tubule Development Mesonephric Epithelium Development Positive Regulation Of JNK Cascade Negative Regulation Of Glomerular Mesangial Cell Proliferation Negative Regulation Of Glomerulus Development Regulation Of Fat Cell Differentiation Mesonephros Development Negative Regulation Of Cellular Metabolic Process Protein Heterooligomerization Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Positive Regulation Of Transferase Activity Negative Regulation Of Mesenchymal Cell Apoptotic Process Involved In Metanephros Development Negative Regulation Of Hydrogen Peroxide Metabolic Process	Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Cellular Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Metabolic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Biosynthetic Process Cellular Response To Radiation Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Metabolic Process Regulation Of RNA Metabolic Process Cellular Response To Light Stimulus Regulation Of Gene Expression Regulation Of Signal Transduction Gene Expression Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Apoptotic Process Regulation Of Cell Proliferation Response To Gamma Radiation Response To Abiotic Stimulus Regulation Of Signaling Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Regulation Of Cell Death DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator RNA Metabolic Process DNA Damage Checkpoint Cellular Response To UV DNA Damage Response, Signal Transduction Resulting In Transcription Mitotic G1 DNA Damage Checkpoint Mitotic G1/S Transition Checkpoint G1 DNA Damage Checkpoint Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Regulation Of Transcription, DNA-templated DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Nucleic Acid-templated Transcription Apoptotic Process Regulation Of RNA Biosynthetic Process Negative Regulation Of Cell Death Programmed Cell Death Signal Transduction In Response To DNA Damage Cell Death Death Mitotic DNA Damage Checkpoint
Tagcloud ?			al antisense discovery enhance et evidence genomic humans igf2r imprinted imprinting issue locus might moorwood murine particularly recent regulating relate rna since suppressor transcript transcripts tumour typically unusual wilms
Tagcloud (Difference) ?			al antisense discovery enhance et evidence genomic humans igf2r imprinted imprinting issue locus might moorwood murine particularly recent regulating relate rna since suppressor transcript transcripts tumour typically unusual wilms
Tagcloud (Intersection) ?