ZNF205 and MEST

Number of citations: 0 (PubMedID 21900206)
Data Source: BioGRID (two hybrid)

		ZNF205	MEST
Name		zinc finger protein 205	mesoderm specific transcript
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Mitochondrion	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Extracellular Exosome
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding	Catalytic Activity Protein Binding Hydrolase Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Biosynthetic Process Positive Regulation Of Hydrogen Peroxide Biosynthetic Process Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway	Mesoderm Development Regulation Of Lipid Storage Response To Retinoic Acid
Pathways		Generic Transcription Pathway	None
GWAS		No GWAS studies recorded	Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971 ) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971 )
Interacting Genes		17 interacting genes: C8orf33 CALCOCO2 CCDC85B CDC37 GOLGA6L9 HDAC6 ILK MAPK6 MDFI MEST PICK1 TNS2 TRAF2 TSGA10 UBQLN2 UBQLN4 WT1	23 interacting genes: APP BAG6 BLOC1S2 C6orf47 CD300C CEP70 CIAO2A CIDEB CMTM3 CRELD2 DBN1 FBXO7 FEZ1 FST GAD2 HGS ING5 KIFAP3 LIME1 MPZL2 RNF19B ZNF205 ZNF579
Entrez ID		7755	4232
HPRD ID		04580	06776
Ensembl ID		ENSG00000122386	ENSG00000106484
Uniprot IDs		O95201	A4D1L9 B4DQW6 Q5EB52
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		Regulation Of Macroautophagy Polyubiquitin Modification-dependent Protein Binding Regulation Of Autophagy Positive Regulation Of Type 2 Mitophagy Autophagosome Regulation Of Autophagosome Maturation Positive Regulation Of Macroautophagy Autophagy Positive Regulation Of Mitophagy Regulation Of Protein-containing Complex Disassembly Positive Regulation Of Autophagy Of Mitochondrion Dendritic Spine Organization Branching Involved In Ureteric Bud Morphogenesis Protein Kinase Binding Cytoplasm TORC2 Complex Disassembly Negative Regulation Of Cell Growth Negative Regulation Of Metanephric Glomerular Mesangial Cell Proliferation Neuron Projection Organization Postsynapse Organization Regulation Of Mitophagy Positive Regulation Of Autophagy Negative Regulation Of Macroautophagy Polyubiquitinated Misfolded Protein Transport Hsp90 Protein Binding Positive Regulation Of Cholangiocyte Proliferation Tumor Necrosis Factor-mediated Signaling Pathway Glial Cell Development Septin Cytoskeleton Regulation Of Cellular Component Organization TRAF2-GSTP1 Complex TORC1 Complex Assembly CD40 Receptor Binding Negative Regulation Of Growth Adrenal Cortex Formation Positive Regulation Of Metanephric Ureteric Bud Development Visceral Serous Pericardium Development Posterior Mesonephric Tubule Development Positive Regulation Of Cellular Response To Oxidative Stress Acetylspermidine Deacetylase Activity Polyamine Deacetylation Positive Regulation Of Catabolic Process Spermidine Deacetylation Peroxidase Inhibitor Activity Regulation Of Autophagy Of Mitochondrion Negative Regulation Of Aggrephagy Tubulin Deacetylase Activity HSP90-CDC37 Chaperone Complex Negative Regulation Of G Protein-coupled Receptor Internalization Nuclear Proteasome Complex	Gamma-tubulin Binding