ZMYM2 and SNIP1

Number of citations of the paper that reports this interaction (PubMedID 15231748)
54

Data Source:
HPRD (two hybrid)

		ZMYM2	SNIP1
Description		zinc finger MYM-type containing 2	Smad nuclear interacting protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol PML Body	Nucleus Nucleoplasm Spliceosomal Complex U2 SnRNP Cytosol U2-type Precatalytic Spliceosome
	Molecular Function	Protein Binding Zinc Ion Binding Ubiquitin Conjugating Enzyme Binding Metal Ion Binding	RNA Binding MRNA Binding Protein Binding Transcription Regulator Inhibitor Activity
	Biological Process	Negative Regulation Of DNA-templated Transcription	MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Regulation Of Gene Expression Regulatory NcRNA-mediated Gene Silencing MiRNA Processing Negative Regulation Of Canonical NF-kappaB Signal Transduction U2-type Prespliceosome Assembly
Pathways		Signaling by cytosolic FGFR1 fusion mutants Signaling by FGFR1 in disease Signaling by FLT3 fusion proteins Signaling by FLT3 fusion proteins Negative Regulation of CDH1 Gene Transcription	mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Adult body size ( 32376654) Facial emotion recognition (happy faces) ( 28608620) Hand grip strength ( 29691431)	Axial length ( 24144296) Eyebrow thickness ( 26926045)
Interacting Genes		32 interacting genes: CEBPE CRBN CREB1 CREBBP ERG FBXL17 FOXP1 FOXP2 FOXP4 FUS GMCL1 HNRNPA2B1 HNRNPH3 IKZF3 PAICS PTBP1 SFPQ SKIL SLC19A4P SMAD3 SMAD4 SNIP1 SREBF2 SUMO1 SUMO2 SUMO3 TSC22D2 UBE2A UBE2I UBTF ZBTB3 ZNF512B	47 interacting genes: CDK6 CREBBP DVL2 DVL3 EIF3C EP300 ESRRG FAF1 GMEB1 GYS1 HIPK1 HIPK3 KRTAP10-6 MAX MYC PHF19 PIAS1 PIAS2 PIAS3 PIAS4 POU2F1 PRPF3 PRPF40A RELA SETDB1 SF3B1 SMAD1 SMAD2 SMAD4 SON SP100 SPANXN2 SRPK2 SRRM4 STK3 TDG TNIP1 TOPORS TSPYL2 TTC14 UBE2I ZBTB9 ZCCHC10 ZCCHC7 ZMYM2 ZMYM5 ZNF451
Entrez ID		7750	79753
HPRD ID		03745	06999
Ensembl ID		ENSG00000121741	ENSG00000163877
Uniprot IDs		A8K126 Q9UBW7	B1AK66 Q8TAD8
PDB IDs			5Z56 5Z57 5Z58 6FF7 7ABG 7ABH 7ABI 7DVQ 8I0P 8I0R
Enriched GO Terms of Interacting Partners?		Nucleoplasm Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process Nucleus Negative Regulation Of RNA Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II Chromatin DNA-binding Transcription Factor Activity Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of DNA-templated Transcription Presynaptic Cytosol Postsynaptic Cytosol RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA Binding Sequence-specific DNA Binding PML Body Chromatin Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Transcription Coactivator Binding Negative Regulation Of Macromolecule Biosynthetic Process Protein Sumoylation Protein Tag Activity Negative Regulation Of Macromolecule Metabolic Process Positive Regulation Of Transforming Growth Factor Beta3 Production Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Negative Regulation Of Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Metabolic Process DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Positive Regulation Of RNA Metabolic Process Macromolecule Metabolic Process Regulation Of MiRNA Transcription Ubiquitin-like Protein Ligase Binding Regulation Of MiRNA Metabolic Process Positive Regulation Of Metabolic Process MiRNA Processing Small Protein Activating Enzyme Binding Transforming Growth Factor Beta Receptor Signaling Pathway Identical Protein Binding	Regulation Of Nucleobase-containing Compound Metabolic Process PML Body Chromatin Regulation Of RNA Metabolic Process Regulation Of Transcription By RNA Polymerase II Regulation Of Macromolecule Metabolic Process Nucleoplasm Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Nucleus Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Metabolic Process Regulation Of Primary Metabolic Process SUMO Transferase Activity Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of RNA Metabolic Process Protein Sumoylation SUMO Ligase Activity Positive Regulation Of RNA Metabolic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of DNA-templated Transcription Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Transcription Coregulator Activity Positive Regulation Of Transcription By RNA Polymerase II DNA Binding Positive Regulation Of Biosynthetic Process SMAD Protein Signal Transduction Positive Regulation Of MiRNA Transcription Negative Regulation Of Macromolecule Metabolic Process Nucleic Acid Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Metabolic Process Negative Regulation Of Biosynthetic Process Positive Regulation Of MiRNA Metabolic Process Transcription Regulator Complex DNA-binding Transcription Factor Binding Nuclear Speck DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Negative Regulation Of Metabolic Process Regulation Of MiRNA Transcription DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Metabolic Process Regulation Of MiRNA Metabolic Process Nucleobase-containing Compound Metabolic Process
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