ZMYM2 and HNRNPH3

Number of citations of the paper that reports this interaction (PubMedID 15975576)
0

Data Source:
HPRD (in vivo)

		ZMYM2	HNRNPH3
Description		zinc finger MYM-type containing 2	heterogeneous nuclear ribonucleoprotein H3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol PML Body	Nucleus Nucleoplasm Spliceosomal Complex Ribonucleoprotein Complex
	Molecular Function	Protein Binding Zinc Ion Binding Ubiquitin Conjugating Enzyme Binding Metal Ion Binding	Nucleic Acid Binding RNA Binding Protein Binding
	Biological Process	Negative Regulation Of DNA-templated Transcription	MRNA Splicing, Via Spliceosome RNA Processing MRNA Processing RNA Splicing Epithelial Cell Differentiation Regulation Of RNA Splicing
Pathways		Signaling by cytosolic FGFR1 fusion mutants Signaling by FGFR1 in disease Signaling by FLT3 fusion proteins Signaling by FLT3 fusion proteins Negative Regulation of CDH1 Gene Transcription
Drugs			Copper
Diseases
GWAS		Adult body size ( 32376654) Facial emotion recognition (happy faces) ( 28608620) Hand grip strength ( 29691431)
Interacting Genes		32 interacting genes: CEBPE CRBN CREB1 CREBBP ERG FBXL17 FOXP1 FOXP2 FOXP4 FUS GMCL1 HNRNPA2B1 HNRNPH3 IKZF3 PAICS PTBP1 SFPQ SKIL SLC19A4P SMAD3 SMAD4 SNIP1 SREBF2 SUMO1 SUMO2 SUMO3 TSC22D2 UBE2A UBE2I UBTF ZBTB3 ZNF512B	100 interacting genes: ADORA2A ANXA11 CCL13 CHERP CRMP1 DDX17 DDX5 EEF1G ERG ERG28 HNRNPA0 HNRNPA1 HNRNPD HNRNPF HNRNPH1 HNRNPU HNRNPUL1 IL7R KAT5 MAPK6 MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR9-3 MIR92A1 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I NCBP3 PIM2 RBM4 RPS4X SLC22A2 TTR UTP14A ZMYM2
Entrez ID		7750	3189
HPRD ID		03745	03818
Ensembl ID		ENSG00000121741	ENSG00000096746
Uniprot IDs		A8K126 Q9UBW7	B4DHY1 P31942 Q53F48
PDB IDs
Enriched GO Terms of Interacting Partners?		Nucleoplasm Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process Nucleus Negative Regulation Of RNA Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II Chromatin DNA-binding Transcription Factor Activity Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of DNA-templated Transcription Presynaptic Cytosol Postsynaptic Cytosol RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA Binding Sequence-specific DNA Binding PML Body Chromatin Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Transcription Coactivator Binding Negative Regulation Of Macromolecule Biosynthetic Process Protein Sumoylation Protein Tag Activity Negative Regulation Of Macromolecule Metabolic Process Positive Regulation Of Transforming Growth Factor Beta3 Production Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Negative Regulation Of Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Metabolic Process DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Positive Regulation Of RNA Metabolic Process Macromolecule Metabolic Process Regulation Of MiRNA Transcription Ubiquitin-like Protein Ligase Binding Regulation Of MiRNA Metabolic Process Positive Regulation Of Metabolic Process MiRNA Processing Small Protein Activating Enzyme Binding Transforming Growth Factor Beta Receptor Signaling Pathway Identical Protein Binding	MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing RISC Complex Regulatory NcRNA-mediated Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression MRNA 3'-UTR Binding MiRNA-mediated Gene Silencing By Inhibition Of Translation Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process MiRNA-mediated Gene Silencing By MRNA Destabilization Extracellular Vesicle Negative Regulation Of Translation Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process MRNA Destabilization RNA Destabilization Positive Regulation Of MRNA Catabolic Process Regulation Of Macromolecule Metabolic Process Positive Regulation Of MRNA Metabolic Process Negative Regulation Of Cytokine Production Regulation Of MRNA Stability Regulation Of Translation Negative Regulation Of Angiogenesis Regulation Of MRNA Metabolic Process Negative Regulation Of Cell Migration Negative Regulation Of Vasculature Development Regulation Of RNA Stability Negative Regulation Of Vascular Endothelial Growth Factor Production Negative Regulation Of Cell Motility Regulation Of Metabolic Process Regulation Of Angiogenesis Negative Regulation Of Locomotion Regulation Of Vasculature Development Negative Regulation Of Multicellular Organismal Process Regulation Of Blood Vessel Endothelial Cell Migration Negative Regulation Of Developmental Process Negative Regulation Of Protein Metabolic Process Regulation Of Endothelial Cell Migration Extracellular Space Negative Regulation Of Blood Vessel Endothelial Cell Migration Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Endothelial Cell Migration Regulation Of Cell Migration Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Cellular Response To Growth Factor Stimulus
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