ZMYM2 and HNRNPA2B1

Number of citations of the paper that reports this interaction (PMID 15975576)
10

Data Source:
HPRD (in vivo)

		ZMYM2	HNRNPA2B1
Gene Name		zinc finger, MYM-type 2	heterogeneous nuclear ribonucleoprotein A2/B1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol PML Body	Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm Membrane Ribonucleoprotein Complex Catalytic Step 2 Spliceosome
	Molecular Function	Zinc Ion Binding Ubiquitin Conjugating Enzyme Binding	Nucleotide Binding RNA Binding Protein Binding Single-stranded Telomeric DNA Binding Poly(A) RNA Binding Pre-mRNA Intronic Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Biological_process	Negative Regulation Of Transcription From RNA Polymerase II Promoter MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Gene Expression Negative Regulation Of MRNA Splicing, Via Spliceosome RNA Transport
Pathways		Signaling by FGFR in disease Signaling by FGFR1 mutants Signaling by FGFR mutants Signaling by FGFR1 fusion mutants	Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS
Protein-Protein Interactions		20 interactors: CEBPE CREB1 FUS HNRNPA2B1 HNRNPH3 PTBP1 RCOR1 SFPQ SKIL SMAD3 SMAD4 SNIP1 SREBF2 SUMO1 SUMO2 UBE2A UBE2I UBTF ZBTB3 ZNF512B	17 interactors: CDKN2A CSNK2A1 CSNK2B ERG HIPK3 HIST3H3 HNRNPL LIG4 MAP4K2 NR4A1 PSMA3 SNRNP70 SREK1 TTF2 VHL YAE1D1 ZMYM2
Entrez ID		7750	3181
HPRD ID		03745	02526
Ensembl ID		ENSG00000121741	ENSG00000122566
Uniprot IDs		Q9UBW7	P22626
PDB IDs			1X4B
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Gene Expression Nucleobase-containing Compound Metabolic Process RNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Gene Expression Nitrogen Compound Metabolic Process Negative Regulation Of Transcription, DNA-templated Regulation Of RNA Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Biosynthetic Process Regulation Of Transcription, DNA-templated Cellular Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Cellular Metabolic Process RNA Processing Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter RNA Biosynthetic Process Regulation Of Metabolic Process MRNA Splicing, Via Spliceosome Protein Sumoylation RNA Splicing, Via Transesterification Reactions Transcription From RNA Polymerase II Promoter RNA Splicing SMAD Protein Complex Assembly Metabolic Process MRNA Processing Regulation Of Transforming Growth Factor Beta2 Production DNA-templated Transcription, Initiation Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Epithelial Cell Differentiation MRNA Metabolic Process Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Splicing Production Of MiRNAs Involved In Gene Silencing By MiRNA Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Cellular Process Regulation Of Protein Catabolic Process Lens Fiber Cell Differentiation Positive Regulation Of Epithelial To Mesenchymal Transition Positive Regulation Of Cell Morphogenesis Involved In Differentiation	Cellular Nitrogen Compound Metabolic Process RNA Metabolic Process Gene Expression Cellular Metabolic Process Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Regulation Of Apoptotic Process Apoptotic Process Negative Regulation Of Cell Death Programmed Cell Death Regulation Of Cell Death Cell Death Death RNA Splicing Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process Negative Regulation Of Catalytic Activity Negative Regulation Of Cellular Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process MRNA Processing Metabolic Process Negative Regulation Of Protein Metabolic Process Negative Regulation Of Cellular Metabolic Process Regulation Of Cell Proliferation Regulation Of Protein Metabolic Process Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Cysteine-type Endopeptidase Activity MRNA Metabolic Process Transcription, DNA-templated Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Metabolic Process Regulation Of Cell Cycle Phase Transition RNA Processing Regulation Of Catalytic Activity Cellular Protein Modification Process RNA Biosynthetic Process DNA Ligation Involved In DNA Recombination Negative Regulation Of Potassium Ion Export Regulation Of Proteolysis Regulation Of RNA Metabolic Process Negative Regulation Of Ubiquitin-protein Transferase Activity Phosphorylation Positive Regulation Of Protein Metabolic Process Negative Regulation Of Transferase Activity Cellular Macromolecule Biosynthetic Process
Tagcloud ?		advanced aggressive cassette challengeable effectively find finger formerly hairpin hcc hepatocellular immunohistochemical intensities library limitations malignancy regions relating reports responsiveness screens sequenced sorafenib stronger successful successive treat zinc	amyotrophic autosomal carriers coding conserved equivocal et ewsr1 exons export familial frontotemporal fus genotyped genotyping lobar nes neurodegeneration pathogenicity r471c relatives sequenced subject substitution taf15 tardbp tdp43 tremor
Tagcloud (Difference) ?		advanced aggressive cassette challengeable effectively find finger formerly hairpin hcc hepatocellular immunohistochemical intensities library limitations malignancy regions relating reports responsiveness screens sorafenib stronger successful successive treat zinc	amyotrophic autosomal carriers coding conserved equivocal et ewsr1 exons export familial frontotemporal fus genotyped genotyping lobar nes neurodegeneration pathogenicity r471c relatives subject substitution taf15 tardbp tdp43 tremor
Tagcloud (Intersection) ?		sequenced