ZSCAN12 and ZSCAN21

Number of citations: 50 (PubMedID 32296183)
Data Source: BioGRID (two hybrid)

		ZSCAN12	ZSCAN21
Name		zinc finger and SCAN domain containing 12	zinc finger and SCAN domain containing 21
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleus
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Male Meiosis I Spermatogenesis Cell Differentiation Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Meiotic Cell Cycle
GWAS		Asthma and major depressive disorder ( 31619474 ) Autism spectrum disorder or schizophrenia ( 28540026 ) Brain morphology (MOSTest) ( 32665545 ) Chronic obstructive pulmonary disease ( 33909500 ) Fish- and plant-related diet ( 32066663 ) Lung cancer ( 28604730 ) Refractive error ( 32231278 ) Sarcoidosis (Lofgren's syndrome vs non-Lofgren's syndrome) ( 26651848 ) Sleep duration (short sleep) ( 30846698 ) Smoking initiation (ever regular vs never regular) ( 30679032 ) Squamous cell lung carcinoma ( 28604730 ) Subcortical volume (MOSTest) ( 32665545 )	Brain morphology (MOSTest) ( 32665545 ) Refractive error ( 32231278 ) Subcortical volume (MOSTest) ( 32665545 )
Interacting Genes		26 interacting genes: BICD2 CENPH CEP70 FAM161A KRTAP10-1 KRTAP10-8 LMNA MID2 MTUS2 PGBD1 RACK1 SCAND1 SRPK2 SSX2IP TFIP11 VCX VLDLR VPS26A ZKSCAN7 ZNF24 ZNF397 ZNF446 ZNF473 ZNF496 ZSCAN21 ZSCAN32	25 interacting genes: APP BRCA1 CAVIN1 CEP70 CLK2 DVL3 KRT40 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-3 OGT PICK1 SCAND1 TRIM41 ZKSCAN7 ZNF396 ZNF446 ZNF483 ZNF496 ZNF837 ZSCAN12 ZSCAN22
Entrez ID		9753	7589
HPRD ID		15767	03162
Ensembl ID		ENSG00000158691	ENSG00000166529
Uniprot IDs		A0A804HJ42 O43309	G3V0F4 Q9Y5A6
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		None	Keratin Filament Intermediate Filament Identical Protein Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Transcription By RNA Polymerase II DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Zinc Ion Binding Regulation Of RNA Metabolic Process DNA Binding