ZSCAN12 and ZNF397

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZSCAN12	ZNF397
Description		zinc finger and SCAN domain containing 12	zinc finger protein 397
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleus Nucleolus Cytoplasm Cytosol Plasma Membrane Microtubule Cytoskeleton
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Protein Homodimerization Activity Metal Ion Binding Protein Heterodimerization Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Negative Regulation Of DNA-templated Transcription
Pathways
Drugs
Diseases
GWAS		Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Brain morphology (MOSTest) ( 32665545) Chronic obstructive pulmonary disease ( 33909500) Fish- and plant-related diet ( 32066663) Lung cancer ( 28604730) Refractive error ( 32231278) Sarcoidosis (Lofgren's syndrome vs non-Lofgren's syndrome) ( 26651848) Sleep duration (short sleep) ( 30846698) Smoking initiation (ever regular vs never regular) ( 30679032) Squamous cell lung carcinoma ( 28604730) Subcortical volume (MOSTest) ( 32665545)	Facial morphology ( 29921221)
Interacting Genes		26 interacting genes: BICD2 CENPH CEP70 FAM161A KRTAP10-1 KRTAP10-8 LMNA MID2 MTUS2 PGBD1 RACK1 SCAND1 SRPK2 SSX2IP TFIP11 VCX VLDLR VPS26A ZKSCAN7 ZNF24 ZNF397 ZNF446 ZNF473 ZNF496 ZSCAN21 ZSCAN32	8 interacting genes: LMO4 OGT PRKAA2 ZKSCAN4 ZNF396 ZNF410 ZSCAN12 ZSCAN22
Entrez ID		9753	84307
HPRD ID		15767	18335
Ensembl ID		ENSG00000158691	ENSG00000186812
Uniprot IDs		A0A804HJ42 O43309	Q8NF99
PDB IDs
Enriched GO Terms of Interacting Partners?			Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Transcription By RNA Polymerase II Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Regulation Of Gene Expression Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of RNA Metabolic Process Regulation Of Macromolecule Metabolic Process Metal Ion Binding Negative Regulation Of Translational Initiation Positive Regulation Of Translational Initiation Regulation Of Metabolic Process Regulation Of Glycolytic Process Protein Localization To Lysosome Cellular Response To Glucose Stimulus Regulation Of Carbohydrate Catabolic Process Positive Regulation Of TORC1 Signaling Nucleus TORC1 Signaling Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Regulation Of ATP Metabolic Process Cellular Response To Carbohydrate Stimulus TOR Signaling Regulation Of Purine Nucleotide Metabolic Process Positive Regulation Of TOR Signaling Intracellular Glucose Homeostasis Zinc Ion Binding Protein Localization To Vacuole [hydroxymethylglutaryl-CoA Reductase (NADPH)] Kinase Activity Regulation Of TORC1 Signaling Histone H2BS36 Kinase Activity DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Regulation Of Translational Initiation DNA Binding Negative Regulation Of Macromolecule Biosynthetic Process Cytoplasmic Translation Protein O-acetylglucosaminyltransferase Activity Ventral Spinal Cord Interneuron Differentiation Response To Glucose Transcription Coregulator Activity Negative Regulation Of Biosynthetic Process Regulation Of Generation Of Precursor Metabolites And Energy Negative Regulation Of Protein-containing Complex Assembly Response To Monosaccharide Regulation Of Phosphorus Metabolic Process Protein Localization To Lipid Droplet Sequence-specific Double-stranded DNA Binding
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