YY1 and YAF2

Number of citations of the paper that reports this interaction (PMID 9016636)
17

Data Source:
HPRD (two hybrid, in vitro)

		YY1	YAF2
Gene Name		YY1 transcription factor	YY1 associated factor 2
Image
Gene Ontology Annotations	Cellular Component	Nucleus Transcription Factor Complex Nuclear Matrix Ino80 Complex PcG Protein Complex	Nucleus Nucleoplasm Cytoplasm
	Molecular Function	Four-way Junction DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Coactivator Activity Transcription Corepressor Activity RNA Binding Protein Binding Zinc Ion Binding Transcription Regulatory Region DNA Binding	Transcription Coactivator Activity Transcription Corepressor Activity Protein Binding Zinc Ion Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Double-strand Break Repair Via Homologous Recombination Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter RNA Localization Cellular Response To DNA Damage Stimulus Spermatogenesis Anterior/posterior Pattern Specification Response To UV-C Positive Regulation Of Gene Expression Cell Differentiation Cellular Response To UV Response To Prostaglandin F Camera-type Eye Morphogenesis Chromosome Organization	Transcription, DNA-templated Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		52 interactors: APP ATF2 ATF6 ATF7 BAP1 BRCA1 CDKN2A CREB1 CRKL E2F2 E2F3 EED EP300 FKBP1A FKBP3 GRN GTF2I HCFC1 HDAC2 HDAC3 HIST1H4A HOXA11 INO80 KAT2B MTA2 MYC NEDD4L NFKB1 NOTCH1 NPM1 NR1H2 PPIA PSMD9 RAF1 RYBP SAP30 SKP2 SLC39A7 SMAD1 SMAD2 SMAD3 SMURF2 SP1 SPRY1 SREBF1 TESK1 TFCP2 TP53 UHRF2 YAF2 ZNF232 ZRANB2	6 interactors: GABPB1 MYCN RING1 SETBP1 YY1 ZFP42
Entrez ID		7528	10138
HPRD ID		02482	09606
Ensembl ID			ENSG00000015153
Uniprot IDs		P25490	Q8IY57
PDB IDs		1UBD 1ZNM	2D9G
Enriched GO Terms of Interacting Partners?		Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Cellular Metabolic Process Gene Expression Transcription, DNA-templated Regulation Of RNA Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Positive Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Transcription, DNA-templated Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of Gene Expression Regulation Of Gene Expression RNA Metabolic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Nitrogen Compound Metabolic Process Negative Regulation Of Biosynthetic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Metabolic Process Positive Regulation Of Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Cellular Metabolic Process Transcription From RNA Polymerase II Promoter Regulation Of Cell Cycle Cellular Response To Growth Factor Stimulus DNA-templated Transcription, Initiation Response To Growth Factor Chromatin Organization Biosynthetic Process Cellular Response To Organic Substance Chromatin Modification Cell Cycle Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Cellular Process Transforming Growth Factor Beta Receptor Signaling Pathway Notch Signaling Pathway Chromosome Organization	Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Camera-type Eye Morphogenesis Regulation Of Gene Expression Response To Prostaglandin F Regulation Of Nitrogen Compound Metabolic Process Transcription, DNA-templated Eye Morphogenesis RNA Biosynthetic Process Organ Morphogenesis Anterior/posterior Pattern Specification Organ Development Organelle Organization RNA Metabolic Process Regulation Of Genetic Imprinting Gene Expression Response To UV-C Camera-type Eye Development Cellular Macromolecule Biosynthetic Process Histone H2A Monoubiquitination Positive Regulation Of Gene Expression Macromolecule Biosynthetic Process Eye Development Histone H2A Ubiquitination Regulation Of Metabolic Process Negative Regulation Of Astrocyte Differentiation Pattern Specification Process Regulation Of Transcription From RNA Polymerase II Promoter System Development Spermatogenesis Male Gamete Generation Histone Monoubiquitination Cartilage Condensation Nucleobase-containing Compound Metabolic Process Sensory Organ Development Negative Regulation Of Cellular Metabolic Process Regulation Of Astrocyte Differentiation Multicellular Organismal Development Heterocycle Metabolic Process Gamete Generation Cellular Aromatic Compound Metabolic Process Biosynthetic Process Histone Ubiquitination Anatomical Structure Development Negative Regulation Of Glial Cell Differentiation Cellular Nitrogen Compound Metabolic Process Protein Monoubiquitination Anatomical Structure Morphogenesis
Tagcloud ?		activates activators adenylyl amp cbp clue creb cyclase cyclic depend discuss dissociates e2f1 exactly examples generating homologue implying machinery messenger myb myod neurotransmitter outline phosphorylates pka predisposition superfamily transported	antagonized c2 calpain cdna cloning eliminated encodes finger fingers greatly isolation mapping message myoblasts myogenic normally potentiates promyogenic proteolysis proteolytic restricted reverses sarcomeric stimulates stimulatory termed x10 yy1 zinc
Tagcloud (Difference) ?		activates activators adenylyl amp cbp clue creb cyclase cyclic depend discuss dissociates e2f1 exactly examples generating homologue implying machinery messenger myb myod neurotransmitter outline phosphorylates pka predisposition superfamily transported	antagonized c2 calpain cdna cloning eliminated encodes finger fingers greatly isolation mapping message myoblasts myogenic normally potentiates promyogenic proteolysis proteolytic restricted reverses sarcomeric stimulates stimulatory termed x10 zinc
Tagcloud (Intersection) ?		yy1