WNT11 and KRTAP10-9

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		WNT11	KRTAP10-9
Gene Name		wingless-type MMTV integration site family, member 11	keratin associated protein 10-9
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Proteinaceous Extracellular Matrix Extracellular Space Cytoplasm	Keratin Filament
	Molecular Function	Ras GTPase Activator Activity Frizzled Binding Protein Kinase Activator Activity Transcription Regulatory Region DNA Binding
	Biological Process	Osteoblast Differentiation Outflow Tract Morphogenesis Protein Phosphorylation Positive Regulation Of Gene Expression Neuron Differentiation Bone Mineralization Negative Regulation Of Cell Growth Adrenal Gland Development Positive Regulation Of Cell Migration Negative Regulation Of Cell Migration Response To Nutrient Levels Positive Regulation Of Ras GTPase Activity Positive Regulation Of Transforming Growth Factor Beta2 Production Protein Localization To Cell Surface Non-canonical Wnt Signaling Pathway Positive Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Cell Fate Commitment Positive Regulation Of Protein Kinase Activity Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Embryonic Skeletal System Development Artery Morphogenesis Positive Regulation Of Stress Fiber Assembly Palate Development Canonical Wnt Signaling Pathway Cloacal Septation Ventricular Septum Morphogenesis Lung-associated Mesenchyme Development Negative Regulation Of Cell Death Ureteric Bud Morphogenesis Negative Regulation Of Cartilage Development Neuroendocrine Cell Differentiation Tight Junction Assembly Cellular Response To Retinoic Acid Mesonephric Duct Development Negative Regulation Of Mesenchymal Cell Proliferation Positive Regulation Of Protein Kinase C Signaling Negative Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Fibroblast Growth Factor Production
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR Signaling by Wnt GPCR ligand binding Metabolic disorders of biological oxidation enzymes WNT ligand biogenesis and trafficking beta-catenin independent WNT signaling WNT ligand secretion is abrogated by the PORCN inhibitor LGK974 Ca2+ pathway Signaling by WNT in cancer Class B/2 (Secretin family receptors) PCP/CE pathway
Drugs
Diseases
GWAS		PR interval ( 20062060)
Protein-Protein Interactions		3 interactors: KRTAP10-7 KRTAP10-9 MDFI	163 interactors: ADAMTSL4 AES ALDH3B1 ALPI ARFGAP1 ATXN7L1 AVPI1 BCL6B C10orf62 C11orf87 C16orf59 C19orf57 C19orf66 C5orf60 C9orf9 CARKD CATIP CATSPER1 CBX2 CCDC26 CD300LG CDKL3 CHIC2 CHRD CHRNG CKS1B CLK4 CNNM3 CRCT1 CREB5 CST9L CXCL16 DHX57 DMRT3 DOCK2 EIF4E2 FAM124B FAM161A FAM74A4 FAM76B FARS2 GABARAPL1 GABARAPL2 GATA2 GLIDR GLP1R GLRX3 GNE GPATCH2L GSTP1 HBG1 HBZ HCK HOXA1 HOXB9 HPCAL1 HSD3B7 IGSF8 INPP5D IQUB ITGB5 KAT5 KIF9 KLHL38 KRT20 KRT83 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP12-1 KRTAP26-1 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-4 LCE1B LCE2A LCE2D LCE3C LCE3E LCE4A LUZP4 MAB21L3 MAPKBP1 MED30 MEOX2 MOBP MT1DP MXI1 NOTCH2NL NPBWR2 NPDC1 NPPB NR1D2 NUFIP2 OTX1 PGAP2 PGLS PIN1 PLSCR1 PRKAB2 PRPF31 PTGER3 PVR PVRL3 RAB7A RHNO1 RSPO2 SCARB1 SCNM1 SLC23A1 SLC6A20 SMARCE1 SMCP SPATA3 SPATA8 SPG7 SPRY1 SPRY2 STK16 TBC1D16 TBC1D23 TGOLN2 THAP10 TNFRSF6B TNP2 TRIM41 TRIM42 TXNDC5 TYMSOS TYRO3 UTP23 WNT11 WT1-AS XCL2 ZBTB24 ZBTB38 ZBTB9 ZFYVE26 ZNF124 ZNF155 ZNF20 ZNF264 ZNF317 ZNF417 ZNF439 ZNF440 ZNF473 ZNF564 ZNF572 ZNF578 ZNF581 ZNF587 ZNF625 ZNF697 ZNF699 ZNF792 ZNF844 ZSCAN21 ZSCAN26
Entrez ID		7481	386676
HPRD ID		04741	11195
Ensembl ID		ENSG00000085741	ENSG00000221837
Uniprot IDs		O96014	P60411
PDB IDs
Enriched GO Terms of Interacting Partners?		Trophoblast Giant Cell Differentiation Cytoplasmic Sequestering Of Transcription Factor Dorsal/ventral Axis Specification Cytoplasmic Sequestering Of Protein Cell Differentiation Involved In Embryonic Placenta Development Activation Of JUN Kinase Activity Negative Regulation Of DNA Binding Negative Regulation Of Transcription Factor Import Into Nucleus Positive Regulation Of JUN Kinase Activity Negative Regulation Of Protein Import Into Nucleus Regulation Of JUN Kinase Activity Negative Regulation Of Protein Localization To Nucleus Regulation Of DNA Binding JNK Cascade Negative Regulation Of Intracellular Protein Transport Regulation Of Transcription Factor Import Into Nucleus Negative Regulation Of Binding Axis Specification Embryonic Placenta Development Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Negative Regulation Of Intracellular Transport Dorsal/ventral Pattern Formation Positive Regulation Of JNK Cascade Embryonic Skeletal System Morphogenesis Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Activation Of MAPK Activity Maintenance Of Protein Location In Cell Maintenance Of Protein Location Maintenance Of Location In Cell Regulation Of JNK Cascade Embryonic Skeletal System Development Regulation Of Protein Import Into Nucleus Negative Regulation Of Protein Transport Regulation Of Stress-activated MAPK Cascade Placenta Development Negative Regulation Of Wnt Signaling Pathway Regulation Of Protein Localization To Nucleus Positive Regulation Of MAP Kinase Activity Regulation Of Nucleocytoplasmic Transport MAPK Cascade Regulation Of Binding Regulation Of Intracellular Protein Transport Activation Of Protein Kinase Activity Skeletal System Morphogenesis Positive Regulation Of Protein Serine/threonine Kinase Activity Signal Transduction By Phosphorylation Regulation Of MAP Kinase Activity Regulation Of Wnt Signaling Pathway	Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Biosynthetic Process Keratinization Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of RNA Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of Metabolic Process Nitrogen Compound Metabolic Process Regulation Of Cellular Process Cellular Process Keratinocyte Differentiation Cellular Metabolic Process Epidermis Development Epidermal Cell Differentiation Lung Growth Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway Negative Regulation Of ERK1 And ERK2 Cascade Regulation Of Phagocytosis Regulation Of Transcription From RNA Polymerase II Promoter Developmental Process Regulation Of Neurotrophin TRK Receptor Signaling Pathway Regulation Of Podosome Assembly Apoptotic Cell Clearance Penetration Of Zona Pellucida Organelle Disassembly Tissue Development Skin Development Epithelium Development Multicellular Organismal Development Bud Elongation Involved In Lung Branching Cellular Response To Lipid Epithelial Tube Branching Involved In Lung Morphogenesis Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Inner Ear Morphogenesis Fertilization Negative Regulation Of ERBB Signaling Pathway Phagocytosis Anatomical Structure Development
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