WNT7A and STRN4

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		WNT7A	STRN4
Gene Name		wingless-type MMTV integration site family, member 7A	striatin, calmodulin binding protein 4
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Proteinaceous Extracellular Matrix Extracellular Space Endoplasmic Reticulum Lumen Golgi Lumen Plasma Membrane Cell Surface	Protein Phosphatase Type 2A Complex Cytoplasm Membrane Dendritic Spine
	Molecular Function	Receptor Binding Frizzled Binding Cytokine Activity Receptor Agonist Activity	Protein Binding Calmodulin Binding Protein Complex Binding Protein Phosphatase 2A Binding Armadillo Repeat Domain Binding
	Biological Process	Embryonic Axis Specification Cartilage Condensation Angiogenesis Chondrocyte Differentiation Neurotransmitter Secretion Sex Differentiation Asymmetric Protein Localization Dorsal/ventral Pattern Formation Positive Regulation Of Endothelial Cell Migration Skeletal Muscle Satellite Cell Activation Skeletal Muscle Satellite Cell Maintenance Involved In Skeletal Muscle Regeneration Cerebellar Granule Cell Differentiation Cell Proliferation In Forebrain Central Nervous System Vasculogenesis Establishment Of Cell Polarity Neuron Differentiation Regulation Of Axon Diameter Response To Estradiol Somatic Stem Cell Maintenance Embryonic Forelimb Morphogenesis Embryonic Hindlimb Morphogenesis Non-canonical Wnt Signaling Pathway Wnt Signaling Pathway Involved In Wound Healing, Spreading Of Epidermal Cells Embryonic Digit Morphogenesis Negative Regulation Of Apoptotic Process Cell Fate Commitment Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of JNK Cascade Somatic Stem Cell Division Stem Cell Development Negative Regulation Of Neurogenesis Synapse Organization Positive Regulation Of Synapse Assembly Palate Development Positive Regulation Of Epithelial Cell Proliferation Involved In Wound Healing Oviduct Development Canonical Wnt Signaling Pathway Uterus Morphogenesis Lens Fiber Cell Development Cellular Response To Transforming Growth Factor Beta Stimulus Positive Regulation Of Canonical Wnt Signaling Pathway	Biological_process
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR WNT ligand secretion is abrogated by the PORCN inhibitor LGK974 Signaling by Wnt Signaling by WNT in cancer Metabolic disorders of biological oxidation enzymes GPCR ligand binding WNT ligand biogenesis and trafficking Class B/2 (Secretin family receptors)
Drugs
Diseases
GWAS		Chronic obstructive pulmonary disease-related biomarkers ( 23144326)	Chronic lymphocytic leukemia ( 18758461)
Protein-Protein Interactions		3 interactors: FZD5 FZD9 STRN4	22 interactors: AK5 ASNS CALM1 CAV1 CLDN12 DDX39B DFFA ECSIT GDF9 JUN KLHDC2 LPPR3 MIF MSANTD2 MTG1 NBEA PBDC1 PI4KA PPBP SLC25A6 WIPI2 WNT7A
Entrez ID		7476	29888
HPRD ID		03341	18125
Ensembl ID			ENSG00000090372
Uniprot IDs		O00755	F5GYK2 F8VYA6 Q59GV6 Q9NRL3
PDB IDs
Enriched GO Terms of Interacting Partners?		Non-canonical Wnt Signaling Pathway Canonical Wnt Signaling Pathway Syncytiotrophoblast Cell Differentiation Involved In Labyrinthine Layer Development Lymphocyte Differentiation Regulation Of Chorionic Trophoblast Cell Proliferation Spemann Organizer Formation Wnt Signaling Pathway Wnt Signaling Pathway Involved In Dorsal/ventral Axis Specification Leukocyte Differentiation Lymphocyte Activation Chorionic Trophoblast Cell Differentiation Chorion Development Regulation Of Tight Junction Assembly Leukocyte Activation Post-embryonic Camera-type Eye Development Branching Involved In Labyrinthine Layer Morphogenesis Hemopoiesis Anterior/posterior Axis Specification, Embryo Cell Activation Immune System Development Labyrinthine Layer Morphogenesis Apoptotic Process Involved In Morphogenesis Dorsal/ventral Axis Specification Labyrinthine Layer Blood Vessel Development Apoptotic Process Involved In Development Embryonic Placenta Morphogenesis Cell Differentiation Involved In Embryonic Placenta Development Placenta Blood Vessel Development Developmental Programmed Cell Death Developmental Induction Positive Regulation Of Interferon-gamma Production Embryonic Axis Specification G-protein Coupled Receptor Signaling Pathway Neuroblast Proliferation Labyrinthine Layer Development Embryonic Camera-type Eye Development Regulation Of Cell Junction Assembly T Cell Differentiation In Thymus Anterior/posterior Axis Specification Positive Regulation Of JUN Kinase Activity Regulation Of JUN Kinase Activity Regulation Of Interferon-gamma Production Stem Cell Proliferation Embryonic Pattern Specification Generation Of Neurons	Regulation Of Protein Autophosphorylation Cellular Response To Starvation Cellular Response To Nutrient Levels Response To Starvation Cellular Response To Extracellular Stimulus Regulation Of Oxidoreductase Activity Negative Regulation Of Protein Autophosphorylation Positive Regulation Of Phosphorylation Regulation Of Phosphorylation Response To External Stimulus Response To Organic Cyclic Compound Cellular Localization Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Negative Regulation Of Cell Death Regulation Of Apoptotic Process Response To Calcium Ion Regulation Of Phosphorus Metabolic Process Regulation Of Cell Death Regulation Of Protein Phosphorylation Response To Wounding Positive Regulation Of Protein Phosphorylation Nitric Oxide Metabolic Process Mitochondrion Organization Reactive Nitrogen Species Metabolic Process Response To Nutrient Levels Regulation Of Nitric-oxide Synthase Activity Cellular Response To Transforming Growth Factor Beta Stimulus Regulation Of Immune System Process Response To Extracellular Stimulus Response To Lipid Response To Transforming Growth Factor Beta Response To Organic Substance Positive Regulation Of Ion Transport Cell Communication Positive Regulation Of Cellular Metabolic Process Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Modification Process Negative Regulation Of Ion Transmembrane Transport Regulation Of Cell Cycle Establishment Of Localization In Cell Regulation Of Membrane Repolarization During Action Potential Positive Regulation Of Prostaglandin Secretion Involved In Immune Response DADP Biosynthetic Process Negative Regulation Of Peptidyl-tyrosine Autophosphorylation Wnt Signaling Pathway Involved In Wound Healing, Spreading Of Epidermal Cells Negative Regulation Of Apoptotic DNA Fragmentation Cellular Response To Potassium Ion Starvation L-asparagine Biosynthetic Process
Tagcloud ?		abcb1b administrated brosis colla1 corroborated dkk1 dkk2 dkk3 dkk4 fi frizzled frzb fz1 fz5 fz7 nano nephrotoxicity osteopontin sfrp tio2 wnt1 wnt10a wnt11 wnt2 wnt3 wnt4 wnt5a wnt6 wnt9a
Tagcloud (Difference) ?		abcb1b administrated brosis colla1 corroborated dkk1 dkk2 dkk3 dkk4 fi frizzled frzb fz1 fz5 fz7 nano nephrotoxicity osteopontin sfrp tio2 wnt1 wnt10a wnt11 wnt2 wnt3 wnt4 wnt5a wnt6 wnt9a
Tagcloud (Intersection) ?