WNT7A

Gene Name		wingless-type MMTV integration site family, member 7A
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Proteinaceous Extracellular Matrix Extracellular Space Endoplasmic Reticulum Lumen Golgi Lumen Plasma Membrane Cell Surface
	Molecular Function	Receptor Binding Frizzled Binding Cytokine Activity Receptor Agonist Activity
	Biological Process	Embryonic Axis Specification Cartilage Condensation Angiogenesis Chondrocyte Differentiation Neurotransmitter Secretion Sex Differentiation Asymmetric Protein Localization Dorsal/ventral Pattern Formation Positive Regulation Of Endothelial Cell Migration Skeletal Muscle Satellite Cell Activation Skeletal Muscle Satellite Cell Maintenance Involved In Skeletal Muscle Regeneration Cerebellar Granule Cell Differentiation Cell Proliferation In Forebrain Central Nervous System Vasculogenesis Establishment Of Cell Polarity Neuron Differentiation Regulation Of Axon Diameter Response To Estradiol Somatic Stem Cell Maintenance Embryonic Forelimb Morphogenesis Embryonic Hindlimb Morphogenesis Non-canonical Wnt Signaling Pathway Wnt Signaling Pathway Involved In Wound Healing, Spreading Of Epidermal Cells Embryonic Digit Morphogenesis Negative Regulation Of Apoptotic Process Cell Fate Commitment Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of JNK Cascade Somatic Stem Cell Division Stem Cell Development Negative Regulation Of Neurogenesis Synapse Organization Positive Regulation Of Synapse Assembly Palate Development Positive Regulation Of Epithelial Cell Proliferation Involved In Wound Healing Oviduct Development Canonical Wnt Signaling Pathway Uterus Morphogenesis Lens Fiber Cell Development Cellular Response To Transforming Growth Factor Beta Stimulus Positive Regulation Of Canonical Wnt Signaling Pathway
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR WNT ligand secretion is abrogated by the PORCN inhibitor LGK974 Signaling by Wnt Signaling by WNT in cancer Metabolic disorders of biological oxidation enzymes GPCR ligand binding WNT ligand biogenesis and trafficking Class B/2 (Secretin family receptors)
Drugs
Diseases
GWAS		Chronic obstructive pulmonary disease-related biomarkers ( 23144326)
Protein-protein Interactions		3 interactors: FZD5 FZD9 STRN4
Entrez ID		7476
HPRD ID		03341
Ensembl ID
Uniprot IDs		O00755
PDB IDs
Enriched GO Terms of Interacting Partners?		Non-canonical Wnt Signaling Pathway Canonical Wnt Signaling Pathway Syncytiotrophoblast Cell Differentiation Involved In Labyrinthine Layer Development Lymphocyte Differentiation Regulation Of Chorionic Trophoblast Cell Proliferation Spemann Organizer Formation Wnt Signaling Pathway Wnt Signaling Pathway Involved In Dorsal/ventral Axis Specification Leukocyte Differentiation Lymphocyte Activation Chorionic Trophoblast Cell Differentiation Chorion Development Regulation Of Tight Junction Assembly Leukocyte Activation Post-embryonic Camera-type Eye Development Branching Involved In Labyrinthine Layer Morphogenesis Hemopoiesis Anterior/posterior Axis Specification, Embryo Cell Activation Immune System Development Labyrinthine Layer Morphogenesis Apoptotic Process Involved In Morphogenesis Dorsal/ventral Axis Specification Labyrinthine Layer Blood Vessel Development Apoptotic Process Involved In Development Embryonic Placenta Morphogenesis Cell Differentiation Involved In Embryonic Placenta Development Placenta Blood Vessel Development Developmental Programmed Cell Death Developmental Induction Positive Regulation Of Interferon-gamma Production Embryonic Axis Specification G-protein Coupled Receptor Signaling Pathway Neuroblast Proliferation Labyrinthine Layer Development Embryonic Camera-type Eye Development Regulation Of Cell Junction Assembly T Cell Differentiation In Thymus Anterior/posterior Axis Specification Positive Regulation Of JUN Kinase Activity Regulation Of JUN Kinase Activity Regulation Of Interferon-gamma Production Stem Cell Proliferation Embryonic Pattern Specification Generation Of Neurons
Tagcloud ?		abcb1b administrated brosis colla1 corroborated dkk1 dkk2 dkk3 dkk4 fi frizzled frzb fz1 fz5 fz7 nano nephrotoxicity osteopontin sfrp tio2 wnt1 wnt10a wnt11 wnt2 wnt3 wnt4 wnt5a wnt6 wnt9a