VIP and PRICKLE1

Number of citations of the paper that reports this interaction (PMID 15009665)
1

Data Source:
HPRD (in vivo)

		VIP	PRICKLE1
Gene Name		vasoactive intestinal peptide	prickle homolog 1 (Drosophila)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Neuronal Cell Body	Nucleus Cytosol Nuclear Membrane
	Molecular Function	Hormone Activity Neuropeptide Hormone Activity Protein Binding	Protein Binding Zinc Ion Binding
	Biological Process	Positive Regulation Of Endothelial Cell Proliferation G-protein Coupled Receptor Signaling Pathway Body Fluid Secretion Learning Or Memory Positive Regulation Of Cell Proliferation Regulation Of Signal Transduction Positive Regulation Of Adenylate Cyclase Activity Involved In G-protein Coupled Receptor Signaling Pathway Regulation Of Protein Localization Negative Regulation Of Apoptotic Process Negative Regulation Of Potassium Ion Transport Positive Regulation Of Protein Catabolic Process Positive Regulation Of Vasodilation MRNA Stabilization Negative Regulation Of Smooth Muscle Cell Proliferation Regulation Of Sensory Perception Of Pain Positive Regulation Of Penile Erection Prolactin Secretion	Neural Tube Closure Protein Import Into Nucleus Positive Regulation Of Protein Ubiquitination Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Cardiac Muscle Cell Myoblast Differentiation
Pathways		Signaling by GPCR GPCR downstream signaling G alpha (s) signalling events	Asymmetric localization of PCP proteins Signaling by Wnt PCP/CE pathway beta-catenin independent WNT signaling
Drugs
Diseases
GWAS			Heart failure ( 20445134) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)
Protein-Protein Interactions		8 interactors: MEOX2 MEP1A MME PRICKLE1 SGTA UBQLN4 VIPR1 VIPR2	4 interactors: PRPF31 SMURF2 UTP14C VIP
Entrez ID		7432	144165
HPRD ID		15950	16341
Ensembl ID		ENSG00000146469	ENSG00000139174
Uniprot IDs		P01282	B3KVG3 B3KVG6 Q96MT3
PDB IDs		2RRH 2RRI
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Cardiac Muscle Cell Myoblast Differentiation Digestion Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Cellular Response To UV-A Creatinine Metabolic Process Regulation Of Proteasomal Protein Catabolic Process Somite Specification Response To UV-A Negative Regulation Of Cardiac Muscle Cell Differentiation Cellular Response To UV-B	Prolactin Secretion Ribonucleoprotein Complex Biogenesis Ubiquitin-dependent SMAD Protein Catabolic Process Positive Regulation Of Adenylate Cyclase Activity Involved In G-protein Coupled Receptor Signaling Pathway Regulation Of Adenylate Cyclase Activity Involved In G-protein Coupled Receptor Signaling Pathway Positive Regulation Of Penile Erection Regulation Of Penile Erection Spliceosomal Tri-snRNP Complex Assembly
Tagcloud ?		acral angiopathy bep bleomycin carboplatin ceb dysfunctions ejaculatory erectile etoposide ifosfamide libido neuropathy nonseminomatous nstgct orchidectomy orgasm paresthesia pct phenomenon polychemotherapy posttreatment pvb raynaud retroperitoneal rrrtm sent substituted vinblastine	autonomously branchiomotor c251x caudal caudally cochlear dissimilar efferents fbm fbms laterally migrate modifies olivo orthologs pcp pial r4 r6 rhombomere ror2 separates vangl2 ventrally wnt5a
Tagcloud (Difference) ?		acral angiopathy bep bleomycin carboplatin ceb dysfunctions ejaculatory erectile etoposide ifosfamide libido neuropathy nonseminomatous nstgct orchidectomy orgasm paresthesia pct phenomenon polychemotherapy posttreatment pvb raynaud retroperitoneal rrrtm sent substituted vinblastine	autonomously branchiomotor c251x caudal caudally cochlear dissimilar efferents fbm fbms laterally migrate modifies olivo orthologs pcp pial r4 r6 rhombomere ror2 separates vangl2 ventrally wnt5a
Tagcloud (Intersection) ?