PRICKLE1

Gene Name		prickle homolog 1 (Drosophila)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytosol Nuclear Membrane
	Molecular Function	Protein Binding Zinc Ion Binding
	Biological Process	Neural Tube Closure Protein Import Into Nucleus Positive Regulation Of Protein Ubiquitination Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Cardiac Muscle Cell Myoblast Differentiation
Pathways		Asymmetric localization of PCP proteins Signaling by Wnt PCP/CE pathway beta-catenin independent WNT signaling
Drugs
Diseases
GWAS		Heart failure ( 20445134) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)
Protein-protein Interactions		4 interactors: PRPF31 SMURF2 UTP14C VIP
Entrez ID		144165
HPRD ID		16341
Ensembl ID		ENSG00000139174
Uniprot IDs		B3KVG3 B3KVG6 Q96MT3
PDB IDs
Enriched GO Terms of Interacting Partners?		Prolactin Secretion Ribonucleoprotein Complex Biogenesis Ubiquitin-dependent SMAD Protein Catabolic Process Positive Regulation Of Adenylate Cyclase Activity Involved In G-protein Coupled Receptor Signaling Pathway Regulation Of Adenylate Cyclase Activity Involved In G-protein Coupled Receptor Signaling Pathway Positive Regulation Of Penile Erection Regulation Of Penile Erection Spliceosomal Tri-snRNP Complex Assembly
Tagcloud ?		autonomously branchiomotor c251x caudal caudally cochlear dissimilar efferents fbm fbms laterally migrate modifies olivo orthologs pcp pial r4 r6 rhombomere ror2 separates vangl2 ventrally wnt5a