PRICKLE1 and VIP

Number of citations of the paper that reports this interaction (PMID 15009665)
1

Data Source:
HPRD (in vivo)

		PRICKLE1	VIP
Gene Name		prickle homolog 1 (Drosophila)	vasoactive intestinal peptide
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytosol Nuclear Membrane	Extracellular Region Neuronal Cell Body
	Molecular Function	Protein Binding Zinc Ion Binding	Hormone Activity Neuropeptide Hormone Activity Protein Binding
	Biological Process	Neural Tube Closure Protein Import Into Nucleus Positive Regulation Of Protein Ubiquitination Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Cardiac Muscle Cell Myoblast Differentiation	Positive Regulation Of Endothelial Cell Proliferation G-protein Coupled Receptor Signaling Pathway Body Fluid Secretion Learning Or Memory Positive Regulation Of Cell Proliferation Regulation Of Signal Transduction Positive Regulation Of Adenylate Cyclase Activity Involved In G-protein Coupled Receptor Signaling Pathway Regulation Of Protein Localization Negative Regulation Of Apoptotic Process Negative Regulation Of Potassium Ion Transport Positive Regulation Of Protein Catabolic Process Positive Regulation Of Vasodilation MRNA Stabilization Negative Regulation Of Smooth Muscle Cell Proliferation Regulation Of Sensory Perception Of Pain Positive Regulation Of Penile Erection Prolactin Secretion
Pathways		Asymmetric localization of PCP proteins Signaling by Wnt PCP/CE pathway beta-catenin independent WNT signaling	Signaling by GPCR GPCR downstream signaling G alpha (s) signalling events
Drugs
Diseases
GWAS		Heart failure ( 20445134) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)
Protein-Protein Interactions		4 interactors: PRPF31 SMURF2 UTP14C VIP	8 interactors: MEOX2 MEP1A MME PRICKLE1 SGTA UBQLN4 VIPR1 VIPR2
Entrez ID		144165	7432
HPRD ID		16341	15950
Ensembl ID		ENSG00000139174	ENSG00000146469
Uniprot IDs		B3KVG3 B3KVG6 Q96MT3	P01282
PDB IDs			2RRH 2RRI
Enriched GO Terms of Interacting Partners?		Prolactin Secretion Ribonucleoprotein Complex Biogenesis Ubiquitin-dependent SMAD Protein Catabolic Process Positive Regulation Of Adenylate Cyclase Activity Involved In G-protein Coupled Receptor Signaling Pathway Regulation Of Adenylate Cyclase Activity Involved In G-protein Coupled Receptor Signaling Pathway Positive Regulation Of Penile Erection Regulation Of Penile Erection Spliceosomal Tri-snRNP Complex Assembly	Negative Regulation Of Cardiac Muscle Cell Myoblast Differentiation Digestion Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Cellular Response To UV-A Creatinine Metabolic Process Regulation Of Proteasomal Protein Catabolic Process Somite Specification Response To UV-A Negative Regulation Of Cardiac Muscle Cell Differentiation Cellular Response To UV-B
Tagcloud ?		autonomously branchiomotor c251x caudal caudally cochlear dissimilar efferents fbm fbms laterally migrate modifies olivo orthologs pcp pial r4 r6 rhombomere ror2 separates vangl2 ventrally wnt5a	acral angiopathy bep bleomycin carboplatin ceb dysfunctions ejaculatory erectile etoposide ifosfamide libido neuropathy nonseminomatous nstgct orchidectomy orgasm paresthesia pct phenomenon polychemotherapy posttreatment pvb raynaud retroperitoneal rrrtm sent substituted vinblastine
Tagcloud (Difference) ?		autonomously branchiomotor c251x caudal caudally cochlear dissimilar efferents fbm fbms laterally migrate modifies olivo orthologs pcp pial r4 r6 rhombomere ror2 separates vangl2 ventrally wnt5a	acral angiopathy bep bleomycin carboplatin ceb dysfunctions ejaculatory erectile etoposide ifosfamide libido neuropathy nonseminomatous nstgct orchidectomy orgasm paresthesia pct phenomenon polychemotherapy posttreatment pvb raynaud retroperitoneal rrrtm sent substituted vinblastine
Tagcloud (Intersection) ?